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2026 data Public-data reference. official source

Neuropathic Pain

Open-data reference.

36 US clinical trials · 16 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 320 participants

Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain

VA Office of Research and Development

NCT05351801

RECRUITING NA 250 participants

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

Texas A&M University

NCT05005026

RECRUITING 250 participants

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

Indiana University

NCT06420141

RECRUITING Phase 2 120 participants

Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy

Virginia Commonwealth University

NCT05259527

RECRUITING Phase 2 80 participants

Ginger Root Extract for Sciatic Pain Individuals

Leslie Shen

NCT06817018

RECRUITING NA 48 participants

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

Texas A&M University

NCT06330181

RECRUITING NA 43 participants

Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation

Ashwin Viswanathan

NCT05968664

RECRUITING 40 participants

Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study

VA Office of Research and Development

NCT05811312

RECRUITING Phase 1 36 participants

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

EicOsis Human Health

NCT06438471

RECRUITING Phase 4 30 participants

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

Margaux M. Salas, PhD

NCT06414356

RECRUITING NA 30 participants

Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

University of Miami

NCT06010251

RECRUITING NA 25 participants

Virtual Reality (VR) Self-Hypnosis Software

Icahn School of Medicine at Mount Sinai

NCT06398847

RECRUITING 25 participants

Diabetic Neuropathy in Spinal Cord Stimulator Patients

University of Chicago

NCT04687215

RECRUITING Phase 1 20 participants

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

University of Miami

NCT05630235

RECRUITING NA 15 participants

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

Medical University of South Carolina

NCT05492188

RECRUITING NA 12 participants

Insula Neuromodulation for Chronic Neuropathic Pain

University of Virginia

NCT05404581

ACTIVE NOT RECRUITING 500 participants

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

InSightec

NCT03100474

ACTIVE NOT RECRUITING Phase 2 450 participants

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

Eli Lilly and Company

NCT06568042

ACTIVE NOT RECRUITING 120 participants

Biomarkers for Pain in Spinal Cord Injury (SCI) Patients

The University of Texas Health Science Center, Houston

NCT00913471

ACTIVE NOT RECRUITING NA 61 participants

Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management

NeuraLace Medical

NCT04795635

ACTIVE NOT RECRUITING 30 participants

Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain

Wake Forest University Health Sciences

NCT05674240

ACTIVE NOT RECRUITING NA 25 participants

Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).

Saint Francis Hospital

NCT06246526

COMPLETED NA 457 participants

Radicle Relief 1: A Study of Health and Wellness Products on Pain and Other Health Outcomes

Radicle Science

NCT05589935

COMPLETED NA 196 participants

Symptom Management Efficacy Study to Reduce Distal Neuropathic Pain

New York University

NCT03855111

COMPLETED NA 67 participants

Virtual Walking for Neuropathic Pain in Spinal Cord Injury

University of Alabama at Birmingham

NCT01884662

COMPLETED Phase 2 51 participants

Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)

St. Jude Children's Research Hospital

NCT01506453

COMPLETED Phase 2 50 participants

BMS-741672 for Diabetic Neuropathic Pain

Bristol-Myers Squibb

NCT00683423

COMPLETED NA 38 participants

Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain

Wake Forest University Health Sciences

NCT04156802

COMPLETED NA 35 participants

Pain Inflammation and Cannabis in HIV

Montefiore Medical Center

NCT05554146

COMPLETED Phase 1 28 participants

Effects of Smoked Marijuana on Neuropathic Pain

Center for Medicinal Cannabis Research

NCT00254761

COMPLETED NA 27 participants

Virtual Reality Walking for Neuropathic Pain in Spinal Cord Injury

University of Alabama at Birmingham

NCT03735017

COMPLETED Phase 1 24 participants

Tariquidar-ondansetron Combination in Neuropathic Pain

Washington University School of Medicine

NCT04603066

COMPLETED 14 participants

Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy

NeuraLace Medical

NCT05935956

COMPLETED NA 12 participants

Veteran Ear Acupuncture Pilot Project

Chillicothe VA Medical Center

NCT04208659

COMPLETED Phase 2 11 participants

The Role of N-acetyl-l-cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients With Chronic Neuropathic Pain

Virginia Commonwealth University

NCT01840345

COMPLETED Phase 1 1 participants

Topical Naloxone to Diagnose Ocular Pain

Seema Capoor

NCT04454281

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 7
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neuropathic Pain Trial Landscape

ClinicalTrials.gov lists 36 US studies indexed under Neuropathic Pain, and 16 of those are currently open to recruitment — roughly 44% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Neuropathic Pain shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Neuropathic Pain is led by NeuraLace Medical with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 36 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neuropathic Pain?

PlainTrial tracks 36 US clinical trials for Neuropathic Pain, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neuropathic Pain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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