Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 16 recruiting now early-phase tilt

Neuropathic Pain: early-phase trial registry

16 of 36 indexed Neuropathic Pain trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #419 of 28,707 conditions by registered trial count.

36 US clinical trials · 16 currently recruiting · #419 of 28,707 conditions by registered trial count

Neuropathic Pain: 36 US clinical trials tracked, 16 recruiting.

Neuropathic Pain is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is NeuraLace Medical, running 2 of these trials.

Enrollment posture brief

Registry condition neuropathic-pain

OPEN 16 | RECR 44% | LATE 1 | EARLY 12 | RANK #419 | SPON 2

Nearest open-share peer: Acute Ischemic Stroke (44% recruiting · 27 trials)

Dysphagia63.9%Cognition50%Neuropathic Pain (this)44%Chronic Myeloid Leukemia38.9%Coronary Disease2.8%
Open-enrollment share among volume-matched conditions near Neuropathic Pain

Neuropathic Pain lists 16 open slots (44% of 36 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Neuropathic Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Neuropathic Pain is recruiting above its size-band peers.

    16 of 36 indexed trials (44.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Neuropathic Pain trials is spread across many organizations.

    NeuraLace Medical accounts for 2 of 36 trials (5.6%). 29 distinct sponsors appear on at least one study for this condition label.

  3. Most Neuropathic Pain trials plan to enrol fewer than 100 people.

    Median target enrolment is 38 among the 36 trials that report a genuine target (sentinel values excluded). 27 of those (75%) plan for fewer than 100 participants.

  4. Neuropathic Pain research is mostly interventional.

    29 interventional and 7 observational studies make up this index (80.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 27Phase 41

Open and recent trials

36 total, page 1 of 1

RECRUITING Phase 2 320 participants

Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain

VA Office of Research and Development

NCT05351801

RECRUITING NA 250 participants

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

Texas A&M University

NCT05005026

RECRUITING 250 participants

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

Indiana University

NCT06420141

RECRUITING Phase 2 120 participants

Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy

Virginia Commonwealth University

NCT05259527

RECRUITING Phase 2 80 participants

Ginger Root Extract for Sciatic Pain Individuals

Leslie Shen

NCT06817018

RECRUITING NA 48 participants

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

Texas A&M University

NCT06330181

RECRUITING NA 43 participants

Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation

Ashwin Viswanathan

NCT05968664

RECRUITING 40 participants

Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study

VA Office of Research and Development

NCT05811312

RECRUITING Phase 1 36 participants

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

EicOsis Human Health

NCT06438471

RECRUITING Phase 4 30 participants

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

Margaux M. Salas, PhD

NCT06414356

RECRUITING NA 30 participants

Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

University of Miami

NCT06010251

RECRUITING NA 25 participants

Virtual Reality (VR) Self-Hypnosis Software

Icahn School of Medicine at Mount Sinai

NCT06398847

RECRUITING 25 participants

Diabetic Neuropathy in Spinal Cord Stimulator Patients

University of Chicago

NCT04687215

RECRUITING Phase 1 20 participants

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

University of Miami

NCT05630235

RECRUITING NA 15 participants

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

Medical University of South Carolina

NCT05492188

RECRUITING NA 12 participants

Insula Neuromodulation for Chronic Neuropathic Pain

University of Virginia

NCT05404581

ACTIVE NOT RECRUITING 500 participants

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

InSightec

NCT03100474

ACTIVE NOT RECRUITING Phase 2 450 participants

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

Eli Lilly and Company

NCT06568042

ACTIVE NOT RECRUITING 120 participants

Biomarkers for Pain in Spinal Cord Injury (SCI) Patients

The University of Texas Health Science Center, Houston

NCT00913471

ACTIVE NOT RECRUITING NA 61 participants

Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management

NeuraLace Medical

NCT04795635

ACTIVE NOT RECRUITING 30 participants

Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain

Wake Forest University Health Sciences

NCT05674240

ACTIVE NOT RECRUITING NA 25 participants

Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).

Saint Francis Hospital

NCT06246526

COMPLETED NA 457 participants

Radicle Relief 1: A Study of Health and Wellness Products on Pain and Other Health Outcomes

Radicle Science

NCT05589935

COMPLETED NA 196 participants

Symptom Management Efficacy Study to Reduce Distal Neuropathic Pain

New York University

NCT03855111

COMPLETED NA 67 participants

Virtual Walking for Neuropathic Pain in Spinal Cord Injury

University of Alabama at Birmingham

NCT01884662

COMPLETED Phase 2 51 participants

Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)

St. Jude Children's Research Hospital

NCT01506453

COMPLETED Phase 2 50 participants

BMS-741672 for Diabetic Neuropathic Pain

Bristol-Myers Squibb

NCT00683423

COMPLETED NA 38 participants

Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain

Wake Forest University Health Sciences

NCT04156802

COMPLETED NA 35 participants

Pain Inflammation and Cannabis in HIV

Montefiore Medical Center

NCT05554146

COMPLETED Phase 1 28 participants

Effects of Smoked Marijuana on Neuropathic Pain

Center for Medicinal Cannabis Research

NCT00254761

COMPLETED NA 27 participants

Virtual Reality Walking for Neuropathic Pain in Spinal Cord Injury

University of Alabama at Birmingham

NCT03735017

COMPLETED Phase 1 24 participants

Tariquidar-ondansetron Combination in Neuropathic Pain

Washington University School of Medicine

NCT04603066

COMPLETED 14 participants

Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy

NeuraLace Medical

NCT05935956

COMPLETED NA 12 participants

Veteran Ear Acupuncture Pilot Project

Chillicothe VA Medical Center

NCT04208659

COMPLETED Phase 2 11 participants

The Role of N-acetyl-l-cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients With Chronic Neuropathic Pain

Virginia Commonwealth University

NCT01840345

COMPLETED Phase 1 1 participants

Topical Naloxone to Diagnose Ocular Pain

Seema Capoor

NCT04454281

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 7
Phase 4 1

Named interventions

Most-linked intervention names on Neuropathic Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
VR Game 2 Other
2 trials
VR Game 1 Other
2 trials
Relief Study Product Usage Dietary supplement
1 trials
Ondansetron 16 mg with Placebo Drug
1 trials
Ondansetron 16 mg with Tariquidar Drug
1 trials
Self-administration of auricular acupuncture with prosthesis Procedure
1 trials
Self-administration of auricular acupuncture without prosthesis Procedure
1 trials

US sites by state

Facility locations filed on Neuropathic Pain trials. A trial with sites in several states counts in each.

Texas 8 trials
California 6 trials
North Carolina 5 trials
Virginia 4 trials
Ohio 4 trials
New York 4 trials
Florida 4 trials
Alabama 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Neuropathic Pain page

36 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neuropathic Pain condition card totals 36 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.