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ClinicalTrials.gov 16 recruiting now early-phase tilt

Movement Disorders: early-phase trial registry

16 of 27 indexed Movement Disorders trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #598 of 28,707 conditions by registered trial count.

27 US clinical trials · 16 currently recruiting · #598 of 28,707 conditions by registered trial count

Movement Disorders: 27 US clinical trials tracked, 16 recruiting.

Movement Disorders is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 3 of these trials.

Enrollment posture brief

Registry condition movement-disorders

OPEN 16 | RECR 59% | LATE 0 | EARLY 2 | RANK #598 | SPON 3

Nearest open-share peer: Preeclampsia (59% recruiting · 49 trials)

Movement Disorders (this)59%Alopecia Areata55.6%Acute Ischemic Stroke44.4%Adenocarcinoma25.9%Acne22.2%
Open-enrollment share among volume-matched conditions near Movement Disorders

Movement Disorders lists 16 open slots (59% of 27 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Movement Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Movement Disorders is recruiting above its size-band peers.

    16 of 27 indexed trials (59.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Movement Disorders trials is spread across many organizations.

    Boston Children's Hospital accounts for 3 of 27 trials (11.1%). 22 distinct sponsors appear on at least one study for this condition label.

  3. Typical Movement Disorders enrolment sits around 100 participants.

    Median target enrolment is 100 among the 27 trials that report a genuine target (sentinel values excluded). 11 of those (40.7%) plan for fewer than 100 participants.

  4. Movement Disorders splits between interventional and observational designs.

    13 interventional and 14 observational studies make up this index (48.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22

Open and recent trials

27 total, page 1 of 1

RECRUITING 2,000 participants

Botulinum Toxin for the Treatment of Involuntary Movement Disorders

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001208

RECRUITING 1,000 participants

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Abbott Medical Devices

NCT04071847

RECRUITING 1,000 participants

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

Target ALS Foundation

NCT05137665

RECRUITING 500 participants

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

Boston Children's Hospital

NCT06585605

RECRUITING 200 participants

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Boston Children's Hospital

NCT05354622

RECRUITING 125 participants

Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water

University of Wisconsin, Milwaukee

NCT05736302

RECRUITING NA 123 participants

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

VA Office of Research and Development

NCT06088355

RECRUITING NA 100 participants

Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

University of Pennsylvania

NCT06848530

RECRUITING NA 100 participants

Analysis of Human Movement With Assistive Devices

Orthocare Innovations

NCT05729061

RECRUITING NA 100 participants

Non-invasive BCI-controlled Assistive Devices

University of Texas at Austin

NCT05183152

RECRUITING 100 participants

A Multicenter Pediatric Deep Brain Stimulation Registry

Boston Children's Hospital

NCT06585618

RECRUITING NA 90 participants

Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders

University of Alabama at Birmingham

NCT04061135

RECRUITING 80 participants

Cognitive Decline Following Deep Brain Stimulation

Medical University of South Carolina

NCT05822388

RECRUITING 60 participants

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

InSightec

NCT05539196

RECRUITING NA 50 participants

Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants

University of California, Los Angeles

NCT07236892

RECRUITING NA 10 participants

Leg Stretching Using an Exoskeleton on Demand for People With Spasticity

VA Office of Research and Development

NCT05926596

ACTIVE NOT RECRUITING NA 20,000 participants

Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)

Sage Bionetworks

NCT02696603

ACTIVE NOT RECRUITING 1,000 participants

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Ohio State University

NCT06357195

ACTIVE NOT RECRUITING 500 participants

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

InSightec

NCT03100474

COMPLETED 300 participants

Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001667

COMPLETED Phase 2 129 participants

Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Novartis Pharmaceuticals

NCT01491932

COMPLETED Phase 2 61 participants

Heart Rate Variability in Response to Metformin Challenge

Woodinville Psychiatric Associates

NCT02500628

COMPLETED NA 35 participants

Golf Instruction Versus Tai Chi for People With Parkinson's Disease

Massachusetts General Hospital

NCT03563807

COMPLETED 34 participants

Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene

Children's Hospital Medical Center, Cincinnati

NCT03892798

COMPLETED 25 participants

Postural Effects of Being Rotated in a Whole Body Gyroscope

Carrick Institute for Graduate Studies

NCT01188161

COMPLETED NA 20 participants

Proprioception and Meditation

University of Miami

NCT03079817

COMPLETED NA 10 participants

Music-listening During Deep Brain Stimulation to Relieve Anxiety

Darlene A. Lobel, MD

NCT03091335

Phase Distribution

PhaseTrial count
Phase 2 2

Named interventions

Most-linked intervention names on Movement Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Rotating Chair Device
1 trials
Proprioceptive Drills Other
1 trials
Yoga Meditation Other
1 trials
Music-listening Other
1 trials
No interventions are planned Other
1 trials
Tai Chi Class Other
1 trials
Golf Instruction Other
1 trials
AFQ056 Drug
1 trials

US sites by state

Facility locations filed on Movement Disorders trials. A trial with sites in several states counts in each.

Massachusetts 6 trials
Washington 5 trials
Pennsylvania 4 trials
Ohio 4 trials
New York 4 trials
Maryland 4 trials
California 4 trials
Texas 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Movement Disorders page

27 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Movement Disorders condition card totals 27 registered trials; most-linked intervention Rotating Chair; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.