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ClinicalTrials.gov 16 recruiting now official registry

Movement Disorders clinical trials

Every US clinical trial registered for Movement Disorders — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

27 US clinical trials · 16 currently recruiting

The research picture

Movement Disorders has 27 registered US clinical trials, 16 of them open to new participants right now — about 59% of the total.

16
recruiting participants now
59%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: Boston Children's Hospital

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 2,000 participants

Botulinum Toxin for the Treatment of Involuntary Movement Disorders

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001208

RECRUITING 1,000 participants

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Abbott Medical Devices

NCT04071847

RECRUITING 1,000 participants

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

Target ALS Foundation

NCT05137665

RECRUITING 500 participants

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

Boston Children's Hospital

NCT06585605

RECRUITING 200 participants

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Boston Children's Hospital

NCT05354622

RECRUITING 125 participants

Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water

University of Wisconsin, Milwaukee

NCT05736302

RECRUITING NA 123 participants

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

VA Office of Research and Development

NCT06088355

RECRUITING NA 100 participants

Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

University of Pennsylvania

NCT06848530

RECRUITING NA 100 participants

Analysis of Human Movement With Assistive Devices

Orthocare Innovations

NCT05729061

RECRUITING NA 100 participants

Non-invasive BCI-controlled Assistive Devices

University of Texas at Austin

NCT05183152

RECRUITING 100 participants

A Multicenter Pediatric Deep Brain Stimulation Registry

Boston Children's Hospital

NCT06585618

RECRUITING NA 90 participants

Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders

University of Alabama at Birmingham

NCT04061135

RECRUITING 80 participants

Cognitive Decline Following Deep Brain Stimulation

Medical University of South Carolina

NCT05822388

RECRUITING 60 participants

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

InSightec

NCT05539196

RECRUITING NA 50 participants

Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants

University of California, Los Angeles

NCT07236892

RECRUITING NA 10 participants

Leg Stretching Using an Exoskeleton on Demand for People With Spasticity

VA Office of Research and Development

NCT05926596

ACTIVE NOT RECRUITING NA 20,000 participants

Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)

Sage Bionetworks

NCT02696603

ACTIVE NOT RECRUITING 1,000 participants

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Ohio State University

NCT06357195

ACTIVE NOT RECRUITING 500 participants

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

InSightec

NCT03100474

COMPLETED 300 participants

Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001667

COMPLETED Phase 2 129 participants

Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Novartis Pharmaceuticals

NCT01491932

COMPLETED Phase 2 61 participants

Heart Rate Variability in Response to Metformin Challenge

Woodinville Psychiatric Associates

NCT02500628

COMPLETED NA 35 participants

Golf Instruction Versus Tai Chi for People With Parkinson's Disease

Massachusetts General Hospital

NCT03563807

COMPLETED 34 participants

Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene

Children's Hospital Medical Center, Cincinnati

NCT03892798

COMPLETED 25 participants

Postural Effects of Being Rotated in a Whole Body Gyroscope

Carrick Institute for Graduate Studies

NCT01188161

COMPLETED NA 20 participants

Proprioception and Meditation

University of Miami

NCT03079817

COMPLETED NA 10 participants

Music-listening During Deep Brain Stimulation to Relieve Anxiety

Darlene A. Lobel, MD

NCT03091335

Phase Distribution

PhaseTrial count
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Movement Disorders Trial Landscape

ClinicalTrials.gov lists 27 US studies indexed under Movement Disorders, and 16 of those are currently open to recruitment — roughly 59% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Movement Disorders shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Movement Disorders is led by Boston Children's Hospital with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Movement Disorders?

PlainTrial tracks 27 US clinical trials for Movement Disorders, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Movement Disorders?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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