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COMPLETED NA

ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors

NCT01827904 · View on ClinicalTrials.gov ↗

Study Summary

The objective of this prospective, randomized, double-blind (to subjects, local site's blinded assessor and Tremor Core Lab assessors), crossover, multi-site, two-arm study (ExAblate treated arm Vs ExAblate Sham treated control arm) is to test the efficacy of treatment using the ExAblate Transcranial System and to further demonstrate safety in medication-refractory tremor in subjects with essential tremor (ET).

Conditions Studied

Interventions

  • DEVICE Transcranial ExAblate
  • DEVICE Sham Transcranial ExAblate

Study Locations (8)

Other

  • Tokyo Women's Medical University (TWMU) — Tokyo
  • Yonsei University Medical Center — Seoul

California

  • Stanford University Medical Center — Stanford

Maryland

  • University of Maryland Medical System — Baltimore

Massachusetts

  • Brigham and Women's Hospital — Boston

Virginia

  • University of Virginia — Charlottesville

Washington

  • Swedish Medical Center — Seattle

Ontario

  • Sunnybrook Health Sciences Centre — Toronto

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2013-05
Est. Completion 2021-02-24
Phase NA

Sponsor

InSightec

76 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01827904

The ClinicalTrials.gov registry entry for NCT01827904 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is InSightec, which has 76 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Essential Tremor appearing as the primary indexed condition, and to 2 interventions — of which Transcranial ExAblate is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01827904 reports 8 study locations spanning 7 distinct geographic areas — top geographies include Other, California, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01827904 about?

NCT01827904 is a clinical study titled "ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors". The objective of this prospective, randomized, double-blind (to subjects, local site's blinded assessor and Tremor Core Lab assessors), crossover, multi-site, two-arm study (ExAblate treated arm Vs ExAblate Sham treated control arm) is to test the efficacy of treatment using the ExAblate Transcrania...

What is the current status of trial NCT01827904?

This trial is currently completed. It is a NA study. The enrollment target is 76 participants. The study started on 2013-05. Estimated completion is 2021-02-24.

What conditions does trial NCT01827904 study?

This clinical trial studies the following conditions: Essential Tremor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01827904?

The interventions under investigation include: Transcranial ExAblate (DEVICE), Sham Transcranial ExAblate (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01827904?

This trial is sponsored by InSightec, which has 76 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01827904 being conducted?

This trial has 8 study locations across California, Maryland, Massachusetts, Virginia, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial