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NCT02313272 · ClinicalTrials.gov registry record · Phase 1

Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas

A Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target

NCT02313272 is a Phase 1 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 32 participants.

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The verdict

NCT02313272, a Phase 1 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

The purpose of this study is to see if the addition of the investigation drug called pembrolizumab (Keytruda®) to radiation therapy and bevacizumab (Avastin®) is safe and can help with controlling the growth of tumors, in participants with recurrent high grade glioma.

Interventions

  • DRUG Pembrolizumab
  • DRUG Bevacizumab
  • RADIATION Hypofractionated Stereotactic Irradiation (HFSRT)

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2015-07-28
Est. Completion 2021-08-09
Phase Phase 1

What the Registry Record Tells You About NCT02313272

The ClinicalTrials.gov registry entry for NCT02313272 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Pembrolizumab is the first listed.

NCT02313272 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02313272 about?

NCT02313272 is a clinical study titled "Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas". The purpose of this study is to see if the addition of the investigation drug called pembrolizumab (Keytruda®) to radiation therapy and bevacizumab (Avastin®) is safe and can help with controlling the growth of tumors, in participants with recurrent high grade glioma.

What is the current status of trial NCT02313272?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2015-07-28. Estimated completion is 2021-08-09.

What interventions are being tested in trial NCT02313272?

The interventions under investigation include: Pembrolizumab (DRUG), Bevacizumab (DRUG), Hypofractionated Stereotactic Irradiation (HFSRT) (RADIATION).

Who is sponsoring clinical trial NCT02313272?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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