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NCT02139358 · ClinicalTrials.gov registry record · Phase 1

Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer

A Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target

NCT02139358 is a Phase 1 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 15 participants.

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The verdict

NCT02139358, a Phase 1 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and activity of gemcitabine plus trastuzumab and pertuzumab in patients with metastatic human epidermal growth factor receptor 2 (HER2)+ breast cancer who have progressed on at least one prior line of chemotherapy plus HER2 targeted agent such as T-DM1, trastuzumab, or lapatinib.

Interventions

  • DRUG Trastuzumab
  • DRUG Gemcitabine
  • DRUG Pertuzumab

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2014-09-05
Est. Completion 2020-03-16
Phase Phase 1

What the Registry Record Tells You About NCT02139358

The ClinicalTrials.gov registry entry for NCT02139358 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Trastuzumab is the first listed.

NCT02139358 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02139358 about?

NCT02139358 is a clinical study titled "Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer". The purpose of this study is to evaluate the safety and activity of gemcitabine plus trastuzumab and pertuzumab in patients with metastatic human epidermal growth factor receptor 2 (HER2)+ breast cancer who have progressed on at least one prior line of chemotherapy plus HER2 targeted agent such as T...

What is the current status of trial NCT02139358?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2014-09-05. Estimated completion is 2020-03-16.

What interventions are being tested in trial NCT02139358?

The interventions under investigation include: Trastuzumab (DRUG), Gemcitabine (DRUG), Pertuzumab (DRUG).

Who is sponsoring clinical trial NCT02139358?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.