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NCT05873439 · ClinicalTrials.gov registry record · Early Phase 1

Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLC

A Early Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Early Phase 1
Development phase
3
Enrollment target

NCT05873439: Completed Early Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

NCT05873439 is a Early Phase 1 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 3 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05873439, a Early Phase 1 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Early Phase 1
Development phase
3 participants
Enrollment target

Study Summary

The purpose of the study is to determine the feasibility of genomically guided radiation therapy (RT) with concurrent chemotherapy in the management of stage II and III non-small cell lung cancer (NSCLC).

Primary Outcome

Rate of Unacceptable Toxicity will be measured during 12 week period following study enrollment. Unacceptable toxicity is defined as any grade 4 or 5 adverse event (AE) probably or definitely related to experimental dose escalated radiation therapy

Interventions

  • RADIATION Genomically Guided Radiation Therapy (RT)

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2023-05-25
Est. Completion 2024-08-21
Phase Early Phase 1

What the finished NCT05873439 record still lists

NCT05873439 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which Genomically Guided Radiation Therapy (RT) is the first listed.

NCT05873439 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05873439 about?

NCT05873439 is a clinical study titled "Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLC". The purpose of the study is to determine the feasibility of genomically guided radiation therapy (RT) with concurrent chemotherapy in the management of stage II and III non-small cell lung cancer (NSCLC).

What is the current status of trial NCT05873439?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 3 participants. The study started on 2023-05-25. Estimated completion is 2024-08-21.

What interventions are being tested in trial NCT05873439?

The interventions under investigation include: Genomically Guided Radiation Therapy (RT) (RADIATION).

Who is sponsoring clinical trial NCT05873439?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05873439's enrollment target sits among peer trials

3 1949th of 2000 higher than 28 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05873439, the US trial registry maintained by the National Library of Medicine. NCT05873439 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.