Eastern Cooperative Oncology Group

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Eastern Cooperative Oncology Group sits in the top decile of US sponsors by registered trial count (#198 of 15,742 sponsors by registered trial count).

141 total trials 4 currently recruiting 121 completed early-phase tilt top decile by trial count

Eastern Cooperative Oncology Group: 141 sponsored US clinical trials, 4 recruiting.

Eastern Cooperative Oncology Group sponsors 141 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 121 completed. 37 of these trials are in Phase 3-4 (later-stage) and 90 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Bladder Cancer, with 3 trials.

Top-decile sponsor footprint

Eastern Cooperative Oncology Group ranks in the top decile of sponsors by registered trial count (#198 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 71/100

121 of 131 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (92.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

141 total, page 2 of 3

COMPLETED Phase 2

Atrasentan in Treating Patients With Locally Recurrent or Metastatic Kidney Cancer

NCT00039429

COMPLETED Phase 2

Perifosine in Treating Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer

NCT00059982

COMPLETED Phase 3

Gemcitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

NCT00058149

COMPLETED Phase 3

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With AML Leukemia

NCT00049517

COMPLETED Phase 2

Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer

NCT00040807

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung Cancer

NCT00041314

COMPLETED Phase 3

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

NCT00046930

COMPLETED Phase 2

Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer

NCT00033657

COMPLETED Phase 2

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

NCT00028678

COMPLETED Phase 3

Paclitaxel With or Without Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

NCT00028990

COMPLETED Phase 2

Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma

NCT00014508

COMPLETED Phase 2

Gefitinib in Treating Patients With Recurrent Metastatic Colorectal Cancer

NCT00025350

COMPLETED Phase 2

Alemtuzumab Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Lymphocytic Leukemia

NCT00006390

COMPLETED Phase 2

Carboplatin Combined With Paclitaxel in Treating Patients With Advanced Thymoma

NCT00010257

COMPLETED Phase 2

Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer

NCT00014118

COMPLETED Phase 2

Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

NCT00005847

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium and Decreased Kidney Function

NCT00005644

COMPLETED Phase 3

Hormone Replacement Therapy for Hot Flashes and/or Vaginal Symptoms in Postmenopausal Women Receiving Tamoxifen for Breast Cancer

NCT00026286

COMPLETED Phase 2

Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer

NCT00006786

COMPLETED Phase 2

Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer

NCT00004860

COMPLETED Phase 2

Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia

NCT00005962

COMPLETED Phase 3

Interferon Alfa-2b With or Without Thalidomide in Treating Patients With Metastatic or Unresectable Kidney Cancer

NCT00005966

COMPLETED Phase 2

Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma

NCT00006385

COMPLETED Phase 2

Comparison of Two Combination Chemotherapy Regimens in Treating Non-small Cell Lung Cancer

NCT00006004

COMPLETED Phase 3

flt3L in Treating Patients With Acute Myeloid Leukemia

NCT00006223

COMPLETED Phase 2

Arsenic Trioxide in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

NCT00006008

COMPLETED Phase 2

Rituximab in Treating Patients With Waldenstrom's Macroglobulinemia

NCT00005609

COMPLETED Phase 3

Fludarabine With or Without Cyclophosphamide in Treating Patients With Chronic Lymphocytic Leukemia

NCT00003764

COMPLETED Phase 2

Carboxyamidotriazole in Treating Patients With Advanced Kidney Cancer

NCT00005045

COMPLETED Phase 2

Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder Cancer

NCT00004223

COMPLETED Phase 1

Gene Therapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer

NCT00004225

COMPLETED Phase 2

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

NCT00003907

COMPLETED Phase 3

Combination Chemotherapy in Treating Women With Stage II or Stage IIIA Breast Cancer That Has Spread to the Lymph Nodes

NCT00004125

COMPLETED NA

Diagnostic Study of Patients With Stage I Testicular Cancer

NCT00003800

COMPLETED Phase 3

Methylphenidate in Treating Patients With Melanoma

NCT00003266

COMPLETED Phase 2

Carboplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer

NCT00003206

COMPLETED Phase 2

PSA Vaccine Therapy in Treating Patients With Advanced Prostate Cancer

NCT00003871

TERMINATED Phase 2

Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia

NCT00003910

COMPLETED Phase 2

Docetaxel Plus Carboplatin in Treating Patients With Advanced Cancer of the Esophagus

NCT00003864

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

NCT00003810

COMPLETED Phase 2

Theophylline in Treating Patients With In Situ, Stage I, or Stage II Chronic Lymphocytic Leukemia

NCT00003808

COMPLETED Phase 3

Cisplatin With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

NCT00003809

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma

NCT00003388

COMPLETED Phase 3

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma

NCT00003389

COMPLETED Phase 2

Denileukin Diftitox in Treating Patients With Non-Hodgkin's Lymphoma

NCT00003615

COMPLETED Phase 2

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

NCT00003309

COMPLETED Phase 2

Trastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT00003881

COMPLETED Phase 3

Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer

NCT00003592

COMPLETED Phase 3

Combination Chemotherapy in Treating Patients With Bladder Cancer

NCT00003701

COMPLETED Phase 3

Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin

NCT00003444

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 87
Phase 3 37

What is open in the Eastern Cooperative Oncology Group pipeline

4 recruiting of 141 indexed (3% open); 121 completed (86%).

Phase mix: 37 late (III/IV) vs 90 early (I/II) (early-phase heavy).

Top condition: Bladder Cancer (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Eastern Cooperative Oncology Group: open-pipeline peers nationwide

Peers matched on 141 registered trials and 3% open enrollment, not the therapeutic-area sidebar.

Eastern Cooperative Oncology Group sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 0%5%10%15%20% Total trials Recruiting share Eastern Cooperative Oncology GroupCase Western Reserve UniversityPurdue UniversityJohnson & Johnson Vision CareMclean HospitalMerz North AmericaVIVUSEnanta PharmaceuticalsSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Eastern Cooperative Oncology Group sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Eastern Cooperative Oncology Group sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 141 trials (± recruiting share)

Sponsors near 3% open enrollment (± trial volume)

What to do with this Eastern Cooperative Oncology Group page

141 registered trials is a research-attention snapshot, not an endorsement of Eastern Cooperative Oncology Group or any single study.

  • 4 of Eastern Cooperative Oncology Group's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Bladder Cancer is the condition Eastern Cooperative Oncology Group studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Bladder Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Eastern Cooperative Oncology Group pipeline card: 141 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.