Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 34 of 35

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Refractory Stage IV Cancer

NCT00057915

COMPLETED Phase 3

Comparison of Oral Valganciclovir and Placebo for the Prevention of Cytomegalovirus (CMV) After Lung Transplantation

NCT00227370

COMPLETED NA

Comparison of Two Programs to Improve Blood Pressure Treatment Adherence

NCT00123058

TERMINATED Phase 4

Testing Pharmacological Therapies for Pregnant Smokers

NCT00224419

COMPLETED Phase 2

Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity

NCT00402480

COMPLETED Phase 3

Exercise Training Program to Improve Clinical Outcomes in Individuals With Congestive Heart Failure

NCT00047437

COMPLETED Phase 2

Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression

NCT00340379

COMPLETED NA

Computer Program in Improving Communication Between Doctors and Patients With Stage IV Cancer

NCT00276627

COMPLETED NA

Coping Skills Training for Early Rheumatoid Arthritis

NCT00056394

COMPLETED Phase 3

Telephone Enhancement Procedure for Continuing Care - 1

NCT00067171

COMPLETED NA

Partner-Assisted Emotional Disclosure for GI Cancer

NCT00734513

COMPLETED Phase 2

Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer

NCT00049309

TERMINATED Phase 1

Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases

NCT00849745

COMPLETED Phase 2

Paroxetine-CR to Treat Post-Traumatic Stress Disorder (PTSD) Symptomatic After Initial Exposure Therapy

NCT00215163

COMPLETED Phase 2

Ph. II Temozolomide + O6-BG in Treatment of Pts w Temozolomide-Resistant Malignant Glioma

NCT00613093

COMPLETED Phase 3

Role of RhuMab-E25 in Reducing Exhaled Nitric Oxide (NO) in Allergic Asthma

NCT00829179

COMPLETED NA

Diet and Exercise-Based Counseling Program Compared With a Standard Counseling Program in Patients With Early-Stage Prostate Cancer

NCT00044980

COMPLETED

Magnetic Resonance Imaging of Atrial Septal Defects

NCT00498446

COMPLETED NA

Project CHEER (Comprehensive Headache Evaluation, Education, Relief)

NCT00417742

COMPLETED Phase 2

EF5 in Assessing Tumor Response to Anticancer Therapy in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

NCT00041028

COMPLETED NA

Study of Health Promotion in Patients With Early-Stage Breast or Prostate Cancer

NCT00037024

COMPLETED NA

Hydroxyurea in Young Children With Sickle Cell Anemia

NCT00519701

COMPLETED Phase 3

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

NCT00023595

COMPLETED Phase 4

Paroxetine-CR (Paxil-CR) in the Treatment of Patients With Fibromyalgia Syndrome

NCT00610610

COMPLETED

Clinical Outcomes and Cost of Gram Negative Bacteremia

NCT02599220

COMPLETED Phase 4

Paroxetine - Controlled Release in the Treatment of Irritable Bowel Syndrome (IBS)

NCT00610909

COMPLETED Phase 1

Umbilical Cord Blood Stem Cell Transplantation in Adults With Advanced Blood Disorders or Cancer

NCT00312429

COMPLETED Phase 2

Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery

NCT00041392

COMPLETED Phase 2

Combined Behavioral/Pharmacological Therapy for Insomnia

NCT00044629

COMPLETED NA

Effect of Brain Lesion Severity on Treatment Response in Late-Life Depression

NCT00339066

COMPLETED Phase 2

ZD 1839 in Treating Patients With Glioblastoma Multiforme in First Relapse

NCT00016991

COMPLETED Phase 2

Amphetamine-Enhanced Stroke Recovery

NCT01905371

COMPLETED Phase 1

Temozolomide and O6-benzylguanine in Treating Patients With Newly Diagnosed, Recurrent, or Progressive Anaplastic Glioma

NCT00006474

TERMINATED Phase 1

Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer

NCT00010127

COMPLETED Phase 1

Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma

NCT00005951

COMPLETED Phase 2

Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors

NCT00005955

COMPLETED Phase 2

Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma

NCT00005081

COMPLETED Phase 1

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

NCT00005952

COMPLETED Phase 2

Temozolomide in Treating Patients With Brain Metastases

NCT00005954

TERMINATED NA

Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in Detecting Colon Cancer

NCT00016029

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Stage III or Stage IV Kidney Cancer

NCT00005816

COMPLETED NA

Biological Therapy in Treating Patients With Advanced Cancer

NCT00005956

COMPLETED Phase 2

Letrozole, Herceptin in Her2neu +, Estrogen Receptor [ER] and/or Progesterone Receptor [PR] Positive, MBC

NCT00134680

COMPLETED Phase 3

Exercise Training Versus Drug Therapy for Treating Depression in Older Adults

NCT00331305

COMPLETED NA

Behavioral Insomnia Therapy for Fibromyalgia

NCT00000397

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer

NCT00004211

COMPLETED Phase 1

Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas

NCT00003463

COMPLETED Phase 1

Flt3L in Treating Patients With Metastatic Colorectal Cancer

NCT00003431

TERMINATED Phase 1

Immunotherapy in Treating Patients With Metastatic Breast Cancer

NCT00003432

TERMINATED Phase 1

Biological Therapy in Stage I, Stage II, or Stage III Surgically Resected Pancreatic Cancer

NCT00003434

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.