Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 33 of 35

COMPLETED Phase 1

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

NCT00612651

COMPLETED Phase 3

Escitalopram (Lexapro®) In Patients With Major Depression With Atypical Features

NCT00610506

COMPLETED

Bipolar Disorder in Late Life

NCT00787930

COMPLETED Phase 1

Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants

NCT00606437

COMPLETED Phase 1

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma

NCT00387933

COMPLETED NA

Group Parent Training for Adolescent Eating Disorders

NCT00672906

COMPLETED Phase 1

Relapse Prevention for Suicidal Dually Diagnosed Youths

NCT00589641

COMPLETED Phase 2

Effects of Duloxetine vs. Escitalopram on Heart Rate Variability in Depression

NCT00215228

COMPLETED Phase 2

Chemotherapy With Monoclonal Antibody and Radioimmunotherapy for High-Risk B-Cell Non-Hodgkins Lymphoma

NCT00577629

COMPLETED NA

Does Echocardiographically Guided Ventriculo-Ventricular Optimization Yield a Sustained Improvement in Echocardiographic Parameters in Cardiac Resynchronization Therapy Patients? (DEVISE CRT)

NCT00737490

COMPLETED NA

Neuroimaging Attentional Impairment During Abstinence

NCT00692406

COMPLETED NA

Evaluation of Parenting Interventions to Decrease Family Risk for Child Maltreatment

NCT00586677

COMPLETED Phase 2

Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas

NCT00268359

COMPLETED Phase 2

Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma

NCT00354913

COMPLETED Phase 1

Preoperative Radiation Therapy for High Risk Prostate Cancer

NCT01041326

COMPLETED Phase 1

Rituximab in the Treatment of Patients With Bullous Pemphigoid

NCT00286325

COMPLETED NA

Evaluation of a Home Visiting Program for First Time Parents

NCT00579449

COMPLETED Phase 2

Comparing Paroxetine and Duloxetine on Cardiovascular Measures

NCT00136383

COMPLETED Phase 1

Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM

NCT00612989

COMPLETED Phase 1

Ph. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic Gliomas

NCT00612638

COMPLETED Phase 2

Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities

NCT00280943

COMPLETED NA

Early Detection of Breast Cancer Using Tomosynthesis Imaging

NCT00637598

COMPLETED Phase 2

Geodon for the Treatment of Refractory Social Anxiety Disorder

NCT00215150

COMPLETED Phase 2

Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder

NCT00215137

COMPLETED NA

DBT Compared to I/GDC for the Treatment of Opiate Addiction in Emotionally Dysregulated Patients. - 1

NCT00218595

COMPLETED NA

Promoting Postpartum Weight Loss in Overweight Women

NCT00212251

COMPLETED Phase 2

Bortezomib With Melphalan and Prednisone for Multiple Myeloma

NCT00734149

COMPLETED Phase 1

Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma

NCT00354068

COMPLETED NA

Quit Smoking Program for Lung Cancer Patients' Families (The Family Ties Project)

NCT00345891

COMPLETED

Genetics of Peripheral Artery Genomics

NCT00615121

COMPLETED Phase 2

Effects of Resistance and Aerobic Exercise on Cardiovascular Health

NCT00275145

COMPLETED Phase 4

Determining the Effects of Risperdal Consta in Patients With Psychotic Disorders and Incomplete Adherence

NCT00215579

COMPLETED Phase 2

Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme

NCT00362921

COMPLETED Phase 2

Risperidone Augmentation for PTSD

NCT00215241

COMPLETED

Virulence Determinants in S Aureus Bacteremia

NCT00319826

COMPLETED Phase 4

Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment

NCT00543296

COMPLETED Phase 2

Quetiapine in Social Anxiety Disorder

NCT00215254

COMPLETED Phase 2

Interventions to Improve Hypertension Control and Reduce Cardiovascular Disease Risk

NCT00201136

COMPLETED NA

Innohep for Prophylaxis of Venous Thromboembolism in Brain Tumor Patients

NCT00629447

COMPLETED NA

Weight Management and Coping Skills Training For Patients With Knee Osteoarthritis

NCT00305890

COMPLETED NA

Macronutrient Regulation of Ghrelin and Peptide YY

NCT02464514

COMPLETED Phase 2

Exercise and Dietary Counseling in Improving Physical Activity, Nutrition, and Quality of Life in Older Long-Term Cancer Survivors Who Are Overweight

NCT00303875

COMPLETED Phase 2

Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure

NCT00078286

COMPLETED NA

ENCORE: Exercise and Nutritional Interventions for Cardiovascular Health

NCT00571844

COMPLETED Phase 2

Second-Line Treatment for Patients With Platinum-Sensitive Ovarian Cancer

NCT00090610

COMPLETED Phase 4

Self System Therapy and Chronic Low Back Pain Trial

NCT00672880

COMPLETED

A Pharmacogenomics Study for Breast Cancer Patients Undergoing Adjuvant Chemotherapy With Doxorubicin (A)/Cyclophosphamide ©) and/or Weekly Paclitaxel

NCT00131963

COMPLETED Phase 3

Treatment of Obsessive Compulsive Disorder in Children

NCT00074815

COMPLETED Phase 1

Combination Chemotherapy and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer

NCT00281788

COMPLETED Phase 2

Survival TRaining for ENhancing Total Health (STRENGTH)

NCT00068458

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.