Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 33 of 35
PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas
NCT00612651
Escitalopram (Lexapro®) In Patients With Major Depression With Atypical Features
NCT00610506
Bipolar Disorder in Late Life
NCT00787930
Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants
NCT00606437
Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma
NCT00387933
Group Parent Training for Adolescent Eating Disorders
NCT00672906
Relapse Prevention for Suicidal Dually Diagnosed Youths
NCT00589641
Effects of Duloxetine vs. Escitalopram on Heart Rate Variability in Depression
NCT00215228
Chemotherapy With Monoclonal Antibody and Radioimmunotherapy for High-Risk B-Cell Non-Hodgkins Lymphoma
NCT00577629
Does Echocardiographically Guided Ventriculo-Ventricular Optimization Yield a Sustained Improvement in Echocardiographic Parameters in Cardiac Resynchronization Therapy Patients? (DEVISE CRT)
NCT00737490
Neuroimaging Attentional Impairment During Abstinence
NCT00692406
Evaluation of Parenting Interventions to Decrease Family Risk for Child Maltreatment
NCT00586677
Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas
NCT00268359
Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma
NCT00354913
Preoperative Radiation Therapy for High Risk Prostate Cancer
NCT01041326
Rituximab in the Treatment of Patients With Bullous Pemphigoid
NCT00286325
Evaluation of a Home Visiting Program for First Time Parents
NCT00579449
Comparing Paroxetine and Duloxetine on Cardiovascular Measures
NCT00136383
Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM
NCT00612989
Ph. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic Gliomas
NCT00612638
Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities
NCT00280943
Early Detection of Breast Cancer Using Tomosynthesis Imaging
NCT00637598
Geodon for the Treatment of Refractory Social Anxiety Disorder
NCT00215150
Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder
NCT00215137
DBT Compared to I/GDC for the Treatment of Opiate Addiction in Emotionally Dysregulated Patients. - 1
NCT00218595
Promoting Postpartum Weight Loss in Overweight Women
NCT00212251
Bortezomib With Melphalan and Prednisone for Multiple Myeloma
NCT00734149
Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma
NCT00354068
Quit Smoking Program for Lung Cancer Patients' Families (The Family Ties Project)
NCT00345891
Genetics of Peripheral Artery Genomics
NCT00615121
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
NCT00275145
Determining the Effects of Risperdal Consta in Patients With Psychotic Disorders and Incomplete Adherence
NCT00215579
Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme
NCT00362921
Risperidone Augmentation for PTSD
NCT00215241
Virulence Determinants in S Aureus Bacteremia
NCT00319826
Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment
NCT00543296
Quetiapine in Social Anxiety Disorder
NCT00215254
Interventions to Improve Hypertension Control and Reduce Cardiovascular Disease Risk
NCT00201136
Innohep for Prophylaxis of Venous Thromboembolism in Brain Tumor Patients
NCT00629447
Weight Management and Coping Skills Training For Patients With Knee Osteoarthritis
NCT00305890
Macronutrient Regulation of Ghrelin and Peptide YY
NCT02464514
Exercise and Dietary Counseling in Improving Physical Activity, Nutrition, and Quality of Life in Older Long-Term Cancer Survivors Who Are Overweight
NCT00303875
Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure
NCT00078286
ENCORE: Exercise and Nutritional Interventions for Cardiovascular Health
NCT00571844
Second-Line Treatment for Patients With Platinum-Sensitive Ovarian Cancer
NCT00090610
Self System Therapy and Chronic Low Back Pain Trial
NCT00672880
A Pharmacogenomics Study for Breast Cancer Patients Undergoing Adjuvant Chemotherapy With Doxorubicin (A)/Cyclophosphamide ©) and/or Weekly Paclitaxel
NCT00131963
Treatment of Obsessive Compulsive Disorder in Children
NCT00074815
Combination Chemotherapy and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer
NCT00281788
Survival TRaining for ENhancing Total Health (STRENGTH)
NCT00068458
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.