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NCT00849745 · ClinicalTrials.gov registry record · Phase 1
Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases
A Phase 1 study, sponsored by Duke University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT00849745: Clinical Trial Phase 1 study, sponsored by Duke University.
NCT00849745 is a Phase 1 study that was terminated before completion, run by Duke University. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00849745, a Phase 1 study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
Autoimmune diseases present a special challenge to clinicians and the aim of this protocol is to serve as a last-line effort for patients with unmanageable disease. The primary purpose of this study is to assess feasibility in terms of toxicity and engraftment of a less toxic, nonablative conditioning regimen of Campath-1H, moderate dose fludarabine, and cyclophosphamide for patients with severe autoimmune diseases.
Interventions
- PROCEDURE Nonmyeloablative allogeneic stem cell transplant
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2003-01 |
| Est. Completion | 2015-07 |
| Phase | Phase 1 |
Why NCT00849745 stopped before completion
NCT00849745 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Nonmyeloablative allogeneic stem cell transplant is the first listed.
NCT00849745 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00849745 about?
NCT00849745 is a clinical study titled "Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases". Autoimmune diseases present a special challenge to clinicians and the aim of this protocol is to serve as a last-line effort for patients with unmanageable disease. The primary purpose of this study is to assess feasibility in terms of toxicity and engraftment of a less toxic, nonablative conditioni...
What is the current status of trial NCT00849745?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2003-01. Estimated completion is 2015-07.
What interventions are being tested in trial NCT00849745?
The interventions under investigation include: Nonmyeloablative allogeneic stem cell transplant (PROCEDURE).
Who is sponsoring clinical trial NCT00849745?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00849745's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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