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NCT00331305 · ClinicalTrials.gov registry record · Phase 3
Exercise Training Versus Drug Therapy for Treating Depression in Older Adults
A Phase 3 study of Depression, sponsored by Duke University.
- Completed
- Registry status
- Phase 3
- Development phase
- 457
- Enrollment target
- 1
- Study location
NCT00331305: Completed Phase 3 study of Depression, sponsored by Duke University.
NCT00331305 is a Phase 3 study of Depression that has completed, run by Duke University. The registered enrollment target is 457 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00331305, a Phase 3 study of Depression, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 457 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate the effectiveness of both center-based and home-based exercise versus the antidepressant drug sertraline in treating depression in middle-aged and older adults.
Conditions Studied
Interventions
- BEHAVIORAL Home-Based Exercise
- DRUG Placebo Pill
- BEHAVIORAL Supervised Exercise
- DRUG Sertraline (Zoloft)
Study Locations (1)
North Carolina
- Duke University Medical Center, Department of Psychiatry and Behavioral Sciences - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 457 participants |
| Start Date | 1999-08 |
| Est. Completion | 2007-05 |
| Phase | Phase 3 |
What the finished NCT00331305 record still lists
NCT00331305 is an interventional study that assigns participants to a tested intervention. The registered 457 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (42% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 4 interventions - of which Home-Based Exercise is the first listed.
NCT00331305 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT00331305 about?
NCT00331305 is a clinical study titled "Exercise Training Versus Drug Therapy for Treating Depression in Older Adults". This study will evaluate the effectiveness of both center-based and home-based exercise versus the antidepressant drug sertraline in treating depression in middle-aged and older adults.
What is the current status of trial NCT00331305?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 457 participants. The study started on 1999-08. Estimated completion is 2007-05.
What conditions does trial NCT00331305 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT00331305?
The interventions under investigation include: Home-Based Exercise (BEHAVIORAL), Placebo Pill (DRUG), Supervised Exercise (BEHAVIORAL), Sertraline (Zoloft) (DRUG).
Who is sponsoring clinical trial NCT00331305?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00331305 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00331305's enrollment target sits among peer trials
457 95th of 679 higher than 585 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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