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NCT02464514 · ClinicalTrials.gov registry record · NA
Macronutrient Regulation of Ghrelin and Peptide YY
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 28
- Enrollment target
NCT02464514: Completed NA study, sponsored by Duke University.
NCT02464514 is a NA study that has completed, run by Duke University. The registered enrollment target is 28 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02464514, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 28 participants
- Enrollment target
Study Summary
The hyperghrelinemia of children with PWS provides a unique model by which to explore the hormonal and metabolic effects of orexigenic hormones in normal and pathologic conditions. An important question to be addressed by this proposed research includes the macro-nutrient regulation of ghrelin and PYY in obese children and children with PWS. As ghrelin antagonists are considered potential future anti-obesity agents, it is essential to gain understanding of the developmental, nutritional and hormonal regulation of this important orexigenic hormone in children.
Primary Outcome
The change in ghrelin levels will be measured before and after meal consumption in children with PWS, and healthy obese controls. Following an overnight 8 hour fast, subjects will be given either a high carbohydrate or high fat meal. Subjects will be allowed 25 minutes to consume everything on their food tray. Blood samples will be obtained before the meal (fasting) and every 30 minutes thereafter for 4 hours.
Interventions
- OTHER High fat meal
- OTHER High carbohydrate meal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2004-01 |
| Est. Completion | 2005-12 |
| Phase | NA |
What the finished NCT02464514 record still lists
NCT02464514 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which High fat meal is the first listed.
NCT02464514 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02464514 about?
NCT02464514 is a clinical study titled "Macronutrient Regulation of Ghrelin and Peptide YY". The hyperghrelinemia of children with PWS provides a unique model by which to explore the hormonal and metabolic effects of orexigenic hormones in normal and pathologic conditions. An important question to be addressed by this proposed research includes the macro-nutrient regulation of ghrelin and P...
What is the current status of trial NCT02464514?
This trial is currently completed. It is a NA study. The enrollment target is 28 participants. The study started on 2004-01. Estimated completion is 2005-12.
What interventions are being tested in trial NCT02464514?
The interventions under investigation include: High fat meal (OTHER), High carbohydrate meal (OTHER).
Who is sponsoring clinical trial NCT02464514?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02464514's enrollment target sits among peer trials
28 1704th of 2000 higher than 293 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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