Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 27 of 35

COMPLETED NA

ENLIGHTEN: Exercise and NutritionaL Interventions for coGnitive and Cardiovascular HealTh ENhancement

NCT01573546

COMPLETED NA

Isolation of Circulating Tumor Cells Using a Novel EMT-Based Capture Method

NCT02025413

COMPLETED

Magnetic Resonance Imaging (MRI) in Motion

NCT02019199

COMPLETED

Personalized Diabetic Kidney Disease Risk Info to Initiate and Maintain Health Behavior Changes

NCT01377688

COMPLETED NA

Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement

NCT01504438

COMPLETED

Vasospasm in Pediatric Traumatic Brain Injury

NCT01461902

COMPLETED NA

New Therapy for Patients With Severe Tinnitus

NCT01480193

COMPLETED

Identifying the Genetic Predictors of Severe Acne Vulgaris and the Outcome of Oral Isotretinoin Treatment

NCT01727440

COMPLETED

Improving Emergency Department Management of Adults With Sickle Cell Disease

NCT01603160

COMPLETED

RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol

NCT01406210

TERMINATED

Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip

NCT01759550

TERMINATED Phase 4

Right Ventricular (RV) Pacing in Early Post-operative Continuous Flow Left Ventricular Assist Device (LVAD)

NCT01446796

COMPLETED NA

Dose-varied Evaluation of Ablavar-enhanced MR Angiography of the Central Veins of the Chest in Healthy Participants

NCT01431300

COMPLETED Phase 2

Meclizine as a Potential Smoking Cessation Treatment

NCT01443858

COMPLETED Phase 4

Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)

NCT01450800

TERMINATED Phase 2

Study Of Abraxane® And Carboplatin As First-Line Treatment For Triple Negative Metastatic Breast Cancer

NCT01207102

COMPLETED NA

Patient and Provider Interventions for Managing Osteoarthritis in Primary Care

NCT01435109

COMPLETED NA

Feasibility of a Stigma Reduction Intervention for Human Immunodeficiency Virus (HIV)-Infected Women

NCT01385241

COMPLETED Phase 3

Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation

NCT01406223

COMPLETED Phase 3

Milnacipran and Neurocognition, Pain and Fatigue in Fibromyalgia : A 13-week Randomized, Placebo Controlled Cross Over Trial

NCT01829243

COMPLETED Phase 2

Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo

NCT01419977

COMPLETED Phase 1

Statin Therapy to Improve Medication Adherence

NCT01894217

COMPLETED Phase 2

Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturia

NCT02151253

COMPLETED NA

Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes

NCT01430221

TERMINATED Phase 2

Trial To Evaluate the Efficacy of Intravenous Iron in Older Adults With Unexplained Anemia

NCT01309659

COMPLETED Phase 1

Sildenafil in Single Ventricle Patients

NCT01169519

COMPLETED NA

Mila Blooms Intervention Study

NCT01473342

COMPLETED NA

Cognitive Behavioral Treatments for Depression in Chronic Illness

NCT01208428

COMPLETED NA

A Novel Optical Spectral Imaging System for Imaging Breast Tumor Margins

NCT01372631

TERMINATED Phase 2

Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM)

NCT01186406

COMPLETED Phase 3

Concurrent Bupropion / Varenicline for Smoking Cessation

NCT01303861

TERMINATED NA

Patient Positioning in Lumbar Fusion Surgery and Its Impact on Spinal Sagittal Balance and Surgeon Satisfaction

NCT01326091

COMPLETED Phase 2

Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection

NCT01191840

COMPLETED

Impact of Blood Storage Duration on Physiologic Measures

NCT01274390

COMPLETED NA

Steps to Health: Targeting Obesity in the Health Care Workplace

NCT01299051

COMPLETED NA

Ehealth: Second Life Impacts Diabetes Education & Self-Management

NCT01186965

TERMINATED NA

Pacing Affects Cardiovascular Endpoints in Patients With Right Bundle-Branch Block (The PACE-RBBB Trial)

NCT01169493

COMPLETED Phase 4

Open Label Use Of RiaStap During Aortic Reconstruction

NCT01300286

COMPLETED NA

Personalized Cardiovascular Risk Information to Initiate and Maintain Health Behavior Changes

NCT01134458

COMPLETED

The Effects of Respiratory Muscle Strength Training (RMST) on Inspiratory and Expiratory Muscle Strength in Adults and Children With Pompe Disease

NCT01701154

TERMINATED NA

Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery

NCT01329692

COMPLETED

Educational Videos to Improve Patient Decision Making and Race Disparities in Implantable Cardioverter Defibrillator Use

NCT00918125

COMPLETED NA

Cell Phone Intervention in Young Adults

NCT01092364

COMPLETED NA

Intervention Study of Communication in Oncologist-Patient Encounters

NCT00994578

COMPLETED Phase 4

Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)

NCT01780389

COMPLETED NA

Cognitive Remediation in 22q11DS

NCT01781923

COMPLETED NA

Reduced Radiation in Patients With Diffuse Large B-cell Lymphoma

NCT01186978

COMPLETED NA

Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers

NCT01343810

COMPLETED Phase 2

Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell Carcinoma

NCT01108445

TERMINATED Phase 3

Esmolol for Treatment of Perioperative Tachycardia

NCT01208402

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.