Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 27 of 35
ENLIGHTEN: Exercise and NutritionaL Interventions for coGnitive and Cardiovascular HealTh ENhancement
NCT01573546
Isolation of Circulating Tumor Cells Using a Novel EMT-Based Capture Method
NCT02025413
Magnetic Resonance Imaging (MRI) in Motion
NCT02019199
Personalized Diabetic Kidney Disease Risk Info to Initiate and Maintain Health Behavior Changes
NCT01377688
Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement
NCT01504438
Vasospasm in Pediatric Traumatic Brain Injury
NCT01461902
New Therapy for Patients With Severe Tinnitus
NCT01480193
Identifying the Genetic Predictors of Severe Acne Vulgaris and the Outcome of Oral Isotretinoin Treatment
NCT01727440
Improving Emergency Department Management of Adults With Sickle Cell Disease
NCT01603160
RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol
NCT01406210
Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip
NCT01759550
Right Ventricular (RV) Pacing in Early Post-operative Continuous Flow Left Ventricular Assist Device (LVAD)
NCT01446796
Dose-varied Evaluation of Ablavar-enhanced MR Angiography of the Central Veins of the Chest in Healthy Participants
NCT01431300
Meclizine as a Potential Smoking Cessation Treatment
NCT01443858
Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
NCT01450800
Study Of Abraxane® And Carboplatin As First-Line Treatment For Triple Negative Metastatic Breast Cancer
NCT01207102
Patient and Provider Interventions for Managing Osteoarthritis in Primary Care
NCT01435109
Feasibility of a Stigma Reduction Intervention for Human Immunodeficiency Virus (HIV)-Infected Women
NCT01385241
Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation
NCT01406223
Milnacipran and Neurocognition, Pain and Fatigue in Fibromyalgia : A 13-week Randomized, Placebo Controlled Cross Over Trial
NCT01829243
Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo
NCT01419977
Statin Therapy to Improve Medication Adherence
NCT01894217
Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturia
NCT02151253
Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes
NCT01430221
Trial To Evaluate the Efficacy of Intravenous Iron in Older Adults With Unexplained Anemia
NCT01309659
Sildenafil in Single Ventricle Patients
NCT01169519
Mila Blooms Intervention Study
NCT01473342
Cognitive Behavioral Treatments for Depression in Chronic Illness
NCT01208428
A Novel Optical Spectral Imaging System for Imaging Breast Tumor Margins
NCT01372631
Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM)
NCT01186406
Concurrent Bupropion / Varenicline for Smoking Cessation
NCT01303861
Patient Positioning in Lumbar Fusion Surgery and Its Impact on Spinal Sagittal Balance and Surgeon Satisfaction
NCT01326091
Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection
NCT01191840
Impact of Blood Storage Duration on Physiologic Measures
NCT01274390
Steps to Health: Targeting Obesity in the Health Care Workplace
NCT01299051
Ehealth: Second Life Impacts Diabetes Education & Self-Management
NCT01186965
Pacing Affects Cardiovascular Endpoints in Patients With Right Bundle-Branch Block (The PACE-RBBB Trial)
NCT01169493
Open Label Use Of RiaStap During Aortic Reconstruction
NCT01300286
Personalized Cardiovascular Risk Information to Initiate and Maintain Health Behavior Changes
NCT01134458
The Effects of Respiratory Muscle Strength Training (RMST) on Inspiratory and Expiratory Muscle Strength in Adults and Children With Pompe Disease
NCT01701154
Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery
NCT01329692
Educational Videos to Improve Patient Decision Making and Race Disparities in Implantable Cardioverter Defibrillator Use
NCT00918125
Cell Phone Intervention in Young Adults
NCT01092364
Intervention Study of Communication in Oncologist-Patient Encounters
NCT00994578
Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)
NCT01780389
Cognitive Remediation in 22q11DS
NCT01781923
Reduced Radiation in Patients With Diffuse Large B-cell Lymphoma
NCT01186978
Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers
NCT01343810
Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell Carcinoma
NCT01108445
Esmolol for Treatment of Perioperative Tachycardia
NCT01208402
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.