Duke University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).

1,725 total trials 187 currently recruiting 1244 completed early-phase tilt top decile by trial count

Duke University: 1,725 sponsored US clinical trials, 187 recruiting.

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Top-decile sponsor footprint

Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,725 total, page 26 of 35

COMPLETED

Post-traumatic Arthritis Associated With Joint Injury

NCT01792791

COMPLETED Phase 4

Time of Intravenous Acetaminophen Administration

NCT01699815

COMPLETED NA

MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery

NCT01691742

COMPLETED NA

Breakfast Nutrition and Inpatient Glycemia

NCT01805414

COMPLETED NA

Measuring Eating, Activity and Strength: Understanding the Response -Using Protein

NCT01715753

COMPLETED Phase 3

Treatment of Acute HIV Infection With Quad Fixed-dose Combination (FDC) Tablet

NCT01694420

TERMINATED NA

Text Message Study

NCT01789697

TERMINATED Phase 4

Phenylephrine Versus Ephedrine in Pre-eclampsia

NCT02025426

COMPLETED NA

Optimal Timing of Double-Wire Technique For Biliary Cannulation at ERCP

NCT02297750

COMPLETED NA

Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya

NCT01822366

COMPLETED NA

Evaluating a Novel Method of Generalizing Emotion Regulation

NCT01653548

COMPLETED NA

Palliative Care in Heart Failure

NCT01589601

COMPLETED NA

Improving Biopsy Experiences Study for Women

NCT01811043

TERMINATED NA

Swept-Source Optical Coherence Tomography for Noninvasive Retinal Vascular Imaging

NCT01834196

COMPLETED

Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias

NCT01730430

COMPLETED NA

Oral Health Intervention Pilot Study for Individuals With Memory Problems

NCT01808235

COMPLETED

Symptomatic Pulmonary Arterial Hypertension After Mitral Valve Surgery

NCT01646541

COMPLETED NA

Integrated Dose Escalation for Advanced, Localized Gynecologic Cancer (The IDEAL - GYN Trial)

NCT01627288

COMPLETED

Use of a Mobile-based App for SCD Patients

NCT01833702

COMPLETED

Heart and Muscle Metabolism in Barth Syndrome

NCT01625663

COMPLETED NA

Caloric Stimulation on Cerebral Blood Flow

NCT01629901

COMPLETED Phase 2

Nitrites, Exercise, and Peripheral Arterial Disease

NCT01684930

COMPLETED NA

Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD

NCT02173561

COMPLETED NA

Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes

NCT01786941

COMPLETED Phase 1

Albuterol in Individuals With Late Onset Pompe Disease (LOPD)

NCT01859624

COMPLETED Phase 1

Pilot Study To Assess Effect of Treatment and Adherence in PD Subjects

NCT01788696

COMPLETED NA

Exploring Massage Benefits for Arthritis of the Knee

NCT01537484

TERMINATED NA

Clinical Evaluation of Direct Dorsal Column Stimulation

NCT02020460

COMPLETED

Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia

NCT01748565

COMPLETED

Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

NCT01720472

TERMINATED Phase 2

Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants

NCT01560507

TERMINATED NA

Pilot Study of Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter Defibrillator

NCT01576042

COMPLETED Phase 4

Once-Daily Asenapine for Schizophrenia

NCT01549041

COMPLETED NA

Effectiveness of Enhanced Terminal Room Disinfection to Prevent Healthcare-associated Infections (HAIs)

NCT01579370

TERMINATED NA

Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE)

NCT02028052

TERMINATED Phase 1

Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia

NCT01491594

COMPLETED

Study of Urethral Mobility in Male Stress Urinary Incontinence Pre- and Post- Placement of Transobturator Sling

NCT01779323

COMPLETED

Patient Self-management and Gene Guided Therapy for Chronic Hepatitis C

NCT02006823

COMPLETED NA

Feasibility of Non-pharmacological Insomnia Therapy in People Living With HIV

NCT01804907

COMPLETED NA

Effect of Broccoli Sprouts Homogenate on SS RBC

NCT01715480

COMPLETED NA

Comparison of Hand Feeding Techniques for Persons With Dementia

NCT01780402

COMPLETED Phase 1

Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia

NCT01640275

TERMINATED NA

Treatment of Vasopressor-induced Ischemia With Botulinum Toxin A

NCT01483209

COMPLETED NA

A Controlled Study of Stem Cell Transplantation Medical Home Care Compared to Standard Hospital Care

NCT01725022

TERMINATED Phase 2

Zevalin and Velcade in Relapsed/Refractory Mantle Cell Lymphoma

NCT01497275

COMPLETED NA

Evaluation of DVD and Internet Decision Aids for Hip and Knee Osteoarthritis: Focus on Health Literacy

NCT01618097

COMPLETED NA

Adaptive Pet Study

NCT01908504

COMPLETED Phase 1

The Effects of Antihistamines on Pre-Pulse Inhibition

NCT01537471

COMPLETED NA

Caregiver Outlook: An Evidence-based Intervention for the Chaplain Toolkit

NCT01768221

COMPLETED

Eating Disorders in Type 1 Diabetes: Mechanisms of Comorbidity

NCT01513746

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What is open in the Duke University pipeline

187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).

Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).

Top condition: Obesity (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Duke University: open-pipeline peers nationwide

Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Duke UniversityUniversity of California, San FranciscoStanford UniversityVA Office of Research and DevelopmentPfizerCarnegie Mellon UniversityCAMC Health SystemUConn HealthHartford Hospital
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,725 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Duke University page

1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.

  • 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.