Duke University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).

1,725 total trials 187 currently recruiting 1244 completed early-phase tilt top decile by trial count

Duke University: 1,725 sponsored US clinical trials, 187 recruiting.

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Top-decile sponsor footprint

Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,725 total, page 20 of 35

COMPLETED

Evaluation of Tumor and Blood Immune Biomarkers in Resected Non-small Cell Lung Cancer

NCT02848872

COMPLETED

Optical Spectroscopy for Cutaneous Cancer

NCT02522793

TERMINATED NA

Transcutaneous Autonomic Modulation in Thoracic Surgery

NCT02783157

TERMINATED

Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced Cancer

NCT02580045

COMPLETED NA

The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk

NCT02736929

COMPLETED NA

Incentivizing Behavior Change Skills to Promote Weight Loss

NCT02691260

COMPLETED NA

Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term

NCT02697916

TERMINATED

Duke Scleroderma Clinic Patient Registry

NCT02851875

TERMINATED NA

Effects of Nicotine Reduction on Smoking Behavior in ADHD Smokers

NCT02599571

COMPLETED NA

Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty

NCT03395990

COMPLETED NA

Chronic Endometritis and IVF

NCT02646930

COMPLETED NA

Preoperative Pain Threshold and Rapid Recover Programs

NCT02740738

COMPLETED NA

NCCN Renal Cell Registry

NCT02677337

COMPLETED NA

Heart Rate Sensing and Response in Persons With Anorexia Nervosa

NCT02579018

COMPLETED NA

iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes

NCT02980627

COMPLETED NA

Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study

NCT02573246

COMPLETED NA

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

NCT02701361

COMPLETED NA

TMS Modulation of Insula-related Brain Networks

NCT02689323

TERMINATED NA

Cognitive Behavioral Strategies and Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: Open Label Study

NCT02528331

COMPLETED

Eliminate Thromboembolism: Improving Anticoagulation in Non-valvular Atrial Fibrillation Patients

NCT02461602

COMPLETED

CTTI Risk Factors for HABP/VABP Study

NCT02689531

COMPLETED

Correlation of Spinopelvic Parameters and Acetabular Cup Orientation

NCT02598700

COMPLETED NA

Addressing Tobacco Use Disparities Through an Innovative Mobile Phone Intervention

NCT02613689

COMPLETED

VTE Prophylaxis Guidelines in Hospitalized Elders

NCT03025100

COMPLETED NA

Single Breath Hold Abdominal MRI

NCT02434471

COMPLETED NA

Efficacy of First Time Anterior Shoulder Decision Tool

NCT02656277

COMPLETED NA

Examining the Role of Expressive Writing (EW) to Improve Resilience

NCT02510898

COMPLETED NA

Effects of Smoking Environments on Craving and Smoking (CameraCue2.0)

NCT02551692

COMPLETED

Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma

NCT02694965

COMPLETED Phase 2

Biopsychosocial Influence on Shoulder Pain

NCT02620579

COMPLETED

HER2+ Breast Cancer Neo-Adjuvant Coordination of Care Program

NCT02616133

COMPLETED NA

Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension

NCT03001427

TERMINATED NA

Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.

NCT02470728

COMPLETED NA

Addressing Tobacco Use Disparities in Rural Older Adults Through an Innovative Mobile Phone Intervention

NCT02510716

COMPLETED NA

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

NCT02516332

COMPLETED NA

Personalized Health Planning in Shared Medical Appointments for Individuals With Type II Diabetes Pilot Study

NCT02471794

COMPLETED NA

Pacing in First-degree AV-block

NCT01985802

COMPLETED

Pompe Telemedicine Developmental Study

NCT02950298

COMPLETED NA

Clinical and Biological Outcomes of Human Milk and Formula Intake After Gastroschisis Repair

NCT02575846

COMPLETED

Real Time In-Vivo Body Surface Dosimetry for External Beam Radiation Therapy

NCT02407977

COMPLETED

Patient Centered Results for Uterine Fibroids

NCT02260752

COMPLETED

Understanding Adaptive Challenges Associated With Male-factor Infertility

NCT02607098

COMPLETED NA

Targeted Pain Coping Skills Training (PCST) for Prevention and Treatment of Persistent Post-Mastectomy Pain

NCT02439437

COMPLETED

Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws

NCT02619838

COMPLETED

ImplemeNtation oF demOnstration pRoject for Health systeMs: Atrial Fibrillation (INFORM-AF) Part 1

NCT02569528

COMPLETED

Measuring Fatigue in Triage: A Pilot Study

NCT02519205

COMPLETED

Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study

NCT02507674

COMPLETED NA

Integrated Child Obesity Treatment Study: Bull City Healthy and Fit

NCT02573142

COMPLETED

Platelets as Regulators of Inflammation in Cardiac Surgery

NCT02568410

COMPLETED NA

Behavioral Weight and Symptom Management for Breast Cancer Survivors and Partners

NCT02574507

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What is open in the Duke University pipeline

187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).

Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).

Top condition: Obesity (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Duke University: open-pipeline peers nationwide

Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Duke UniversityUniversity of California, San FranciscoStanford UniversityVA Office of Research and DevelopmentPfizerCarnegie Mellon UniversityCAMC Health SystemUConn HealthHartford Hospital
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,725 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Duke University page

1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.

  • 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.