Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03001427 · ClinicalTrials.gov registry record · NA
Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 140
- Enrollment target
NCT03001427 is a NA study that has completed, run by Duke University. The registered enrollment target is 140 participants.
The verdict
NCT03001427, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
Study Summary
This application proposes to extend an ongoing NHLBI clinical trial (NCT02342808) examining the efficacy of a lifestyle intervention combining the Dietary Approaches to Stop Hypertension (DASH) diet with caloric restriction and aerobic exercise to lower and control BP in individuals with RH. In the parent trial, participants with RH will be randomized to either: (1) a 4-month adjunctive lifestyle intervention designed to lower BP through exercise and diet (C-LIFE), or; (2) a standardized education and physician advice (SEPA) control condition. The current protocol will collect additional assessments of neurocognition (executive function, processing speed, and memory), endothelial function (brachial artery flow-mediated dilation), and cerebrovascular reserve (a measure of prefrontal cortex tissue oxygenation) in 120 participants at baseline, following completion of the 4-month intervention, and again after one year, in order to examine neurocognitive improvements and their potential mediators.
Interventions
- BEHAVIORAL Structured center-based lifestyle intervention
- BEHAVIORAL Standard education and physician advice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2016-01 |
| Est. Completion | 2020-12-14 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03001427
The ClinicalTrials.gov registry entry for NCT03001427 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Structured center-based lifestyle intervention is the first listed.
NCT03001427 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03001427 about?
NCT03001427 is a clinical study titled "Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension". This application proposes to extend an ongoing NHLBI clinical trial (NCT02342808) examining the efficacy of a lifestyle intervention combining the Dietary Approaches to Stop Hypertension (DASH) diet with caloric restriction and aerobic exercise to lower and control BP in individuals with RH. In the ...
What is the current status of trial NCT03001427?
This trial is currently completed. It is a NA study. The enrollment target is 140 participants. The study started on 2016-01. Estimated completion is 2020-12-14.
What interventions are being tested in trial NCT03001427?
The interventions under investigation include: Structured center-based lifestyle intervention (BEHAVIORAL), Standard education and physician advice (BEHAVIORAL).
Who is sponsoring clinical trial NCT03001427?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.