Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02783157 · ClinicalTrials.gov registry record · NA
Transcutaneous Autonomic Modulation in Thoracic Surgery
A NA study, sponsored by Duke University.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT02783157: Clinical Trial NA study, sponsored by Duke University.
NCT02783157 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02783157, a NA study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
In this study, the investigators aim to determine whether non-invasive autonomic modulation decreases inflammation and complications after thoracic surgery. The investigators will test the hypothesis that low-level transcutaneous vagal nerve stimulation (LLVNS) during major thoracic surgery reduces inflammation and complications, particularly postoperative atrial fibrillation (POAF). This will be a prospective randomized pilot trial of 200 patients undergoing major thoracic surgery including lobectomy, bilobectomy, or pneumonectomy via either video-assisted thoracoscopic (VAT) or open thoracotomy. Patients will be randomized to receive ether a) LLVNS (n=100) or b) sham LLVNS (n=100) during their procedure. All patients will receive standardized anesthetic, surgical, and post-surgical care. The primary outcome in this study will be time to occurrence of in-hospital POAF, which will be compared between groups using Cox proportional hazards models. Secondary outcomes will be ICU and hospital length of stay, postoperative morbidity, postoperative mortality, and serologic markers of inflammation.
Interventions
- DEVICE Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS)
- DEVICE Sham LLVNS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2016-05 |
| Est. Completion | 2020-02-21 |
| Phase | NA |
Why NCT02783157 stopped before completion
NCT02783157 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS) is the first listed.
NCT02783157 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02783157 about?
NCT02783157 is a clinical study titled "Transcutaneous Autonomic Modulation in Thoracic Surgery". In this study, the investigators aim to determine whether non-invasive autonomic modulation decreases inflammation and complications after thoracic surgery. The investigators will test the hypothesis that low-level transcutaneous vagal nerve stimulation (LLVNS) during major thoracic surgery reduces ...
What is the current status of trial NCT02783157?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2016-05. Estimated completion is 2020-02-21.
What interventions are being tested in trial NCT02783157?
The interventions under investigation include: Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS) (DEVICE), Sham LLVNS (DEVICE).
Who is sponsoring clinical trial NCT02783157?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02783157's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia