Duke University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).

1,725 total trials 187 currently recruiting 1244 completed early-phase tilt top decile by trial count

Duke University: 1,725 sponsored US clinical trials, 187 recruiting.

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Top-decile sponsor footprint

Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,725 total, page 19 of 35

COMPLETED NA

Goals for Reaching Optimum Wellness (GROWell)

NCT02904473

COMPLETED Phase 4

Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery

NCT02829944

COMPLETED NA

Brief Mood Enhancement Intervention

NCT02954965

COMPLETED NA

ICAN Symptoms Duke-NUS

NCT02787993

COMPLETED

CTC Immune Checkpoint

NCT02456571

COMPLETED Phase 4

Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

NCT02995915

TERMINATED NA

The Feasibility and Efficacy of an Extremely Brief Mindfulness Practice

NCT02953444

COMPLETED NA

Addressing Barriers to Adult Hearing Healthcare

NCT02928107

COMPLETED NA

Coherence Imaging of the Cervical Epithelium

NCT02903394

COMPLETED NA

Pompe Disease QMUS and EIM

NCT02742298

COMPLETED NA

Virtual vs. Traditional Physical Therapy Following Total Knee Replacement

NCT02914210

TERMINATED

The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort

NCT02838108

COMPLETED

Pediatric Obesity Observational Prospective Trial

NCT03139877

COMPLETED Phase 4

Safety and Immunogenicity of Simultaneous Tdap and IIV in Pregnant Women

NCT02783170

COMPLETED

Pediatric Metabolism and Microbiome Repository

NCT02959034

COMPLETED NA

Study on Sit to Quit Phone Intervention

NCT02840435

TERMINATED

Study on Smoking Cessation and Cost Outcomes in the Duke Smoking Cessation Program

NCT02845687

COMPLETED NA

Using TMS to Increase Executive Function in Older Adults

NCT02767323

COMPLETED

Stress-Delta Biomarkers for Acute Coronary Syndrome Risk Stratification

NCT02717702

COMPLETED NA

ICanSTEP : Increasing Physical Activity With Text Messaging

NCT02627079

COMPLETED NA

Patient-Empowered Mobile Technology in Hospitalized Patients (TRU-PAIN)

NCT02895841

COMPLETED

Magnetic Resonance Imaging (MRI) Solely For Liver Stereotactic Body Radiation Therapy (SBRT)

NCT02722395

COMPLETED

Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHD

NCT02897362

COMPLETED NA

Ventral Tegmental Area (VTA) Self-Activation in Attention Deficit Hyperactivity Disorder (ADHD)

NCT02723708

COMPLETED NA

Mobile Contingency Management for Marijuana and Tobacco Cessation

NCT02869451

COMPLETED Phase 2

Gabapentin as an Adjunct to Perioperative Pain Management Regimens for Uterine Aspiration

NCT02725710

COMPLETED

Pokemon Go and Physical Activity

NCT02888314

TERMINATED NA

Effects of E-cigarettes (ECIGs) on Pulmonary Inflammation and Behavior in HIV Infected Smokers

NCT02848586

TERMINATED NA

Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)

NCT02813447

COMPLETED NA

Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest

NCT02834065

COMPLETED

Analyzing Retinal Microanatomy in ROP

NCT02887157

COMPLETED NA

Quality of Life in Patients With Primary Sclerosing Cholangitis

NCT02712736

COMPLETED NA

Pain Coping Skills for Colorectal Cancer Survivors

NCT02706301

COMPLETED Phase 4

Predischarge Initiation of Ivabradine in the Management of Heart Failure (PRIME-HF)

NCT02827500

COMPLETED NA

Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy

NCT02819973

COMPLETED NA

Effect of Urethral Analgesia on Voiding

NCT02823431

COMPLETED

Point of Care 3D Ultrasound for Various Applications: A Pilot Study

NCT02831556

COMPLETED Phase 1

PrEP SMART Phase I Trial

NCT02895893

TERMINATED NA

Diagnostic Utility of MRI in Female Patients With Nipple Discharge: A Prospective Trial

NCT02818946

COMPLETED NA

Provider-Patient Communication Coaching

NCT02783742

COMPLETED

Multi-Drug Resistant Organism Network

NCT03646227

COMPLETED

CALYPSO Pilot Study: Machine Learning Based Predictions of Surgical Complications

NCT02828475

COMPLETED NA

Families on Track: A Digital Health Behavioral Intervention for Parents Seeking Treatment for Their Child With Obesity

NCT02767440

COMPLETED

A Pilot Study Investigating the Effect of Chemotherapy on the Tumoral Immunoprofile of Gynecologic Cancers

NCT02824328

TERMINATED NA

Adaptive Optics for Ophthalmic Technologies

NCT02826655

TERMINATED NA

Effectiveness of ROTEM-based Coagulation Surveillance on Reducing Blood Product Utilization During Complex Spine Surgery

NCT02758184

COMPLETED

Identification of Tongue Involvement in Late-Onset Pompe Disease

NCT02765828

COMPLETED

Recruiting African American Fathers/ Sons

NCT02811848

COMPLETED NA

A Quality Improvement Approach to the Management of Chronic Lymphocytic Leukemia

NCT02619604

COMPLETED NA

A mHealth Behavioral Cancer Pain Protocol for Medically Underserved Communities

NCT02783755

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What is open in the Duke University pipeline

187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).

Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).

Top condition: Obesity (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Duke University: open-pipeline peers nationwide

Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Duke UniversityUniversity of California, San FranciscoStanford UniversityVA Office of Research and DevelopmentPfizerCarnegie Mellon UniversityCAMC Health SystemUConn HealthHartford Hospital
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,725 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Duke University page

1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.

  • 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.