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NCT02848872 · ClinicalTrials.gov registry record
Evaluation of Tumor and Blood Immune Biomarkers in Resected Non-small Cell Lung Cancer
A clinical trial, sponsored by Duke University.
- Completed
- Registry status
- 25
- Enrollment target
NCT02848872: Completed study, sponsored by Duke University.
NCT02848872 is a clinical trial that has completed, run by Duke University. The registered enrollment target is 25 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02848872 has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- 25 participants
- Enrollment target
Study Summary
The hypothesis of this study is that functional tumor infiltrating lymphocyte (TIL) isolation from resected lung cancer specimens is feasible, allowing determination of tumor antigen-specific T cell reactivities. The primary objective of this study is to investigate the feasibility of isolating functional tumor infiltrating lymphocytes s(TILs) to determine tumor antigen-specific T cell re-activities in 30 resected lung tumor specimens. Successful isolation of TILs will be defined as collecting 1x10-6 viable, CD45+ mononuclear cells or greater from tumors containing \>/=1 gram of excess tissue. If successful isolation of TILs can be obtained from \>/= 66% of resected tumor specimens, the protocol will be considered feasible. The primary exploratory objective is to identify immunologic signatures that predict clinical outcomes from cytotoxic chemotherapy and/or immunotherapy.
Primary Outcome
Successful isolation of TILs will be defined as collecting 1x10-6 viable, CD45+ mononuclear cells or greater from tumors containing \>/= 1 gm excess tissue in 30 resected lung tumor specimens.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2016-05 |
| Est. Completion | 2019-04-02 |
What the finished NCT02848872 record still lists
NCT02848872 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 25 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02848872 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02848872 about?
NCT02848872 is a clinical study titled "Evaluation of Tumor and Blood Immune Biomarkers in Resected Non-small Cell Lung Cancer". The hypothesis of this study is that functional tumor infiltrating lymphocyte (TIL) isolation from resected lung cancer specimens is feasible, allowing determination of tumor antigen-specific T cell reactivities. The primary objective of this study is to investigate the feasibility of isolating func...
What is the current status of trial NCT02848872?
This trial is currently completed. The enrollment target is 25 participants. The study started on 2016-05. Estimated completion is 2019-04-02.
Who is sponsoring clinical trial NCT02848872?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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