Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02568410 · ClinicalTrials.gov registry record
Platelets as Regulators of Inflammation in Cardiac Surgery
A clinical trial, sponsored by Duke University.
- Completed
- Registry status
- 99
- Enrollment target
NCT02568410 is a clinical trial that has completed, run by Duke University. The registered enrollment target is 99 participants.
The verdict
NCT02568410 has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- 99 participants
- Enrollment target
Study Summary
Platelets are increasingly recognized as a potent and ubiquitously present source of inflammatory activation. Importantly, antiplatelet therapy has been shown to significantly reduce major adverse events such as renal injury in cardiac surgery patients. However, in current practice, concerns of excessive bleeding-not platelet activation and thrombosis-shape clinical decisions. The investigators have recently seen, that a significant drop in platelet numbers following cardiac surgery is associated with increased mortality and risk of acute kidney injury. The investigators hypothesize that such thrombocytopenia is a result of excessive perioperative platelet activation and resultant release of inflammatory and tissue injurious signals by activated platelets. Platelet activation will be characterized during and after cardiac surgery and examine its correlation with inflammatory responses and perioperative end-organ injury.
Interventions
- PROCEDURE coronary artery bypass grafting using cardiopulmonary bypass
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 99 participants |
| Start Date | 2015-10 |
| Est. Completion | 2019-05 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02568410
The ClinicalTrials.gov registry entry for NCT02568410 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 99 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which coronary artery bypass grafting using cardiopulmonary bypass is the first listed.
NCT02568410 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02568410 about?
NCT02568410 is a clinical study titled "Platelets as Regulators of Inflammation in Cardiac Surgery". Platelets are increasingly recognized as a potent and ubiquitously present source of inflammatory activation. Importantly, antiplatelet therapy has been shown to significantly reduce major adverse events such as renal injury in cardiac surgery patients. However, in current practice, concerns of exce...
What is the current status of trial NCT02568410?
This trial is currently completed. The enrollment target is 99 participants. The study started on 2015-10. Estimated completion is 2019-05.
What interventions are being tested in trial NCT02568410?
The interventions under investigation include: coronary artery bypass grafting using cardiopulmonary bypass (PROCEDURE).
Who is sponsoring clinical trial NCT02568410?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.