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NCT03170258 · ClinicalTrials.gov registry record · NA
Self-activation in Individuals With and Without Nicotine Dependence
A NA study, sponsored by Duke University.
- Terminated
- Registry status
- NA
- Development phase
- 46
- Enrollment target
NCT03170258: Clinical Trial NA study, sponsored by Duke University.
NCT03170258 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 46 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03170258, a NA study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
Study Summary
The purpose of this study is to see if a non-medication intervention can increase motivation and reward processing to non-drug reward cues (for example, a picture of one's favorite food) in individuals with and without nicotine dependence by observing brain activity using electroencephalography (EEG) and/or functional magnetic resonance imaging (fMRI). The investigators hypothesize that learning to increase brain activity to non-drug cues may improve reward responses and motivation to non-drug cues, and for individuals who smoke, may eventually result in improved smoking cessation outcomes.
Primary Outcome
The investigators will examine the change in brain activation in the target region (e.g., VTA) during the task. This includes prior to, during, and following real-time neurofeedback. Reported is the percent signal change from baseline (last 3 volumes of prior count condition).
Interventions
- DEVICE Neurofeedback (from fMRI and/or EEG)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2018-02-28 |
| Est. Completion | 2022-07-05 |
| Phase | NA |
Why NCT03170258 stopped before completion
NCT03170258 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Neurofeedback (from fMRI and/or EEG) is the first listed.
NCT03170258 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03170258 about?
NCT03170258 is a clinical study titled "Self-activation in Individuals With and Without Nicotine Dependence". The purpose of this study is to see if a non-medication intervention can increase motivation and reward processing to non-drug reward cues (for example, a picture of one's favorite food) in individuals with and without nicotine dependence by observing brain activity using electroencephalography (EEG...
What is the current status of trial NCT03170258?
This trial is currently terminated. It is a NA study. The enrollment target is 46 participants. The study started on 2018-02-28. Estimated completion is 2022-07-05.
What interventions are being tested in trial NCT03170258?
The interventions under investigation include: Neurofeedback (from fMRI and/or EEG) (DEVICE).
Who is sponsoring clinical trial NCT03170258?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03170258's enrollment target sits among peer trials
46 1402nd of 2000 higher than 590 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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