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NCT03283878 · ClinicalTrials.gov registry record · Phase 4
Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial
A Phase 4 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 4
- Development phase
- 1,770
- Enrollment target
NCT03283878 is a Phase 4 study that has completed, run by Duke University. The registered enrollment target is 1,770 participants.
The verdict
NCT03283878, a Phase 4 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 1,770 participants
- Enrollment target
Study Summary
The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection in elective primary TKA. The investigators hypothesize that a single dose of prophylactic antibiotic administered within 60 minutes before the incision is not an effective way to prevent PJI in elective primary total knee arthroplasty (TKA). The investigators also hypothesize that the prolonged delivery (24 hours) of antibiotic prophylaxis after surgery does not further reduce the incidence of PJI in elective primary TKA. Duke University is the only site recruiting both primary total knee arthroplasty and unilateral knee arthroplasty.
Interventions
- DRUG Cefazolin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,770 participants |
| Start Date | 2017-10-24 |
| Est. Completion | 2025-08-22 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03283878
The ClinicalTrials.gov registry entry for NCT03283878 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 1,770 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Cefazolin is the first listed.
NCT03283878 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03283878 about?
NCT03283878 is a clinical study titled "Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial". The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection...
What is the current status of trial NCT03283878?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 1,770 participants. The study started on 2017-10-24. Estimated completion is 2025-08-22.
What interventions are being tested in trial NCT03283878?
The interventions under investigation include: Cefazolin (DRUG).
Who is sponsoring clinical trial NCT03283878?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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