Dana-Farber Cancer Institute

781 total trials 112 currently recruiting 449 completed

Dana-Farber Cancer Institute sponsors 781 registered US clinical trials on ClinicalTrials.gov, 112 of them currently recruiting, and 449 completed. 15 of these trials are in Phase 3-4 (later-stage) and 492 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 53 trials.

Trial Pipeline

781 total, page 4 of 16

ACTIVE NOT RECRUITING NA

Genetic Testing for All Breast Cancer Patients (GET FACTS)

NCT04245176

ACTIVE NOT RECRUITING Phase 2

A Phase 2 Study of Mirvetuximab Soravtansine (IMGN853) and Pembrolizumab in Endometrial Cancer (EC)

NCT03835819

ACTIVE NOT RECRUITING Phase 1

Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts

NCT03974217

ACTIVE NOT RECRUITING

A Pilot Study of Quantitative Tumor Oxygen Measurements in Cervical Cancer

NCT03970083

ACTIVE NOT RECRUITING Phase 1

A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT

NCT03912064

ACTIVE NOT RECRUITING NA

GENetic Education Risk Assessment and TEsting Study

NCT03762590

ACTIVE NOT RECRUITING Phase 1

'ADVANCE' (A Pilot Trial)

NCT03858322

ACTIVE NOT RECRUITING

Prospective Study of the Prosigna Assay on Neoadjuvant Clinical Decision-making in Women With HR+/Her2- Breast Cancer

NCT03749421

ACTIVE NOT RECRUITING Phase 2

NIMBUS: Nivolumab Plus Ipilimumab in Metastatic Hypermutated HER2-negative Breast Cancer

NCT03789110

ACTIVE NOT RECRUITING

Elevate! : An Elderly Breast Cancer Cohort Study

NCT03818087

ACTIVE NOT RECRUITING Phase 1

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

NCT03740334

ACTIVE NOT RECRUITING Phase 1

DAPHNe: Paclitaxel/Trastuzumab/Pertuzumab in HER2-Positive BC

NCT03716180

ACTIVE NOT RECRUITING Phase 2

AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma

NCT03668340

ACTIVE NOT RECRUITING Phase 1

Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AML

NCT03709758

ACTIVE NOT RECRUITING Phase 1

Olaparib + Sapacitabine in BRCA Mutant Breast Cancer

NCT03641755

ACTIVE NOT RECRUITING NA

Physical Activity, Proliferation and Immune Markers in Benign Breast Tissue

NCT03657628

ACTIVE NOT RECRUITING Phase 2

Niraparib in Patients With Pancreatic Cancer

NCT03601923

ACTIVE NOT RECRUITING Phase 2

ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer

NCT03587740

ACTIVE NOT RECRUITING Phase 2

Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL

NCT03580928

ACTIVE NOT RECRUITING Phase 1

Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS

NCT03534323

ACTIVE NOT RECRUITING Phase 2

Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis

NCT03483012

ACTIVE NOT RECRUITING NA

Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma

NCT03422003

ACTIVE NOT RECRUITING Phase 2

Neodjuvant Nivolumab and Lirilumab, Followed by Surgery, Followed by Adjuvant Nivolumab and Lirilumab, in SCCHN

NCT03341936

ACTIVE NOT RECRUITING NA

Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases

NCT03391362

ACTIVE NOT RECRUITING Phase 2

A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

NCT03392246

ACTIVE NOT RECRUITING Phase 2

Carboplatin +/- Nivolumab in Metastatic Triple Negative Breast Cancer

NCT03414684

ACTIVE NOT RECRUITING Phase 2

Study Of Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer

NCT02876302

ACTIVE NOT RECRUITING Phase 2

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

NCT03333616

ACTIVE NOT RECRUITING NA

PORTAL: Patient-reported Outcomes After Routine Treatment of Atypical Lesions

NCT03070236

ACTIVE NOT RECRUITING Phase 2

Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)

NCT03141671

ACTIVE NOT RECRUITING Phase 2

Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma

NCT03236428

ACTIVE NOT RECRUITING NA

Optimizing Brachytherapy Application and Delivery With MRI Guidance for Gynecologic Cancer

NCT03277469

ACTIVE NOT RECRUITING Phase 2

Palbociclib After CDK and Endocrine Therapy (PACE)

NCT03147287

ACTIVE NOT RECRUITING Phase 1

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

NCT03152318

ACTIVE NOT RECRUITING Phase 2

Targeting PD-1 Therapy Resistance With Focused High or High and Low Dose Radiation in SCCHN

NCT03085719

ACTIVE NOT RECRUITING Phase 1

Osimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

NCT03122717

ACTIVE NOT RECRUITING NA

Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial

NCT03075072

ACTIVE NOT RECRUITING Phase 2

A Phase II Study of Venetoclax in Combination With Dose-adjusted EPOCH-R or R-CHOP for Patients With Richter's Syndrome

NCT03054896

ACTIVE NOT RECRUITING Phase 3

Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

NCT03020030

ACTIVE NOT RECRUITING

Systematic Hereditary Pancreatic Cancer Risk Assessment and Implications for Personalized Therapy

NCT03060720

ACTIVE NOT RECRUITING Phase 2

A Study of Abemaciclib in Recurrent Glioblastoma

NCT02981940

ACTIVE NOT RECRUITING Phase 2

Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone

NCT02880319

ACTIVE NOT RECRUITING Phase 2

Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

NCT02912572

ACTIVE NOT RECRUITING Phase 2

A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib

NCT02873962

ACTIVE NOT RECRUITING Phase 2

Window Study of Nivolumab With or Without Ipilimumab in Squamous Cell Carcinoma of the Oral Cavity

NCT02919683

ACTIVE NOT RECRUITING Phase 1

A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma

NCT02852655

ACTIVE NOT RECRUITING NA

Matched Targeted Therapy For High-Risk Leukemias and Myelodysplastic Syndrome

NCT02670525

ACTIVE NOT RECRUITING NA

Implementation of a System-level Tobacco Treatment Intervention

NCT02816697

ACTIVE NOT RECRUITING Phase 2

Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)

NCT02764541

ACTIVE NOT RECRUITING Phase 1

ACY-1215 in Combination With BCR Pathway Inhibitors in Relapsed CLL

NCT02787369

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Phase Distribution

PhaseTrial count
Phase 1 181
Phase 2 311
Phase 3 14
Phase 4 1

What the Pipeline for Dana-Farber Cancer Institute Shows

According to the ClinicalTrials.gov registry, Dana-Farber Cancer Institute is linked to 781 US clinical trials across every stage of research activity. Of those, 112 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 449 are already marked complete, representing roughly 57% of the total.

The phase mix for Dana-Farber Cancer Institute reports 15 late-stage studies (Phase 3 and Phase 4 combined) and 492 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Dana-Farber Cancer Institute is Breast Cancer with 53 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.