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NCT04789486 · ClinicalTrials.gov registry record · Phase 1

Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer

A Phase 1 study of Non-Small Cell Lung Cancer and Advanced Pancreatic Adenocarcinoma, sponsored by Dana-Farber Cancer Institute.

Recruiting
Registry status
Phase 1
Development phase
100
Enrollment target
2
Study locations

NCT04789486 is a Phase 1 study of Non-Small Cell Lung Cancer and Advanced Pancreatic Adenocarcinoma that is actively recruiting participants, run by Dana-Farber Cancer Institute. The registered enrollment target is 100 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (85% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT04789486, a Phase 1 study of Non-Small Cell Lung Cancer and Advanced Pancreatic Adenocarcinoma, is actively recruiting participants, sponsored by Dana-Farber Cancer Institute.

RECRUITING
Registry status
Phase 1
Development phase
100 participants
Enrollment target
2
Study locations

Study Summary

This research study is being done to help determine the safety and efficacy of gadolinium based nanoparticle, Activation and Guidance of Irradiation X (AGuIX), used in conjunction with MR-guided stereotactic body radiation therapy (SBRT) in the treatment of pancreatic cancer and lung tumors.

Interventions

  • DRUG AGuIX
  • RADIATION Radiotherapy

Study Locations (2)

Massachusetts

  • Brigham and Women's Hospital - Boston
  • Dana Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2021-05-27
Est. Completion 2027-09-10
Phase Phase 1

Sponsor

Dana-Farber Cancer Institute

781 total trials

What the Registry Record Tells You About NCT04789486

The ClinicalTrials.gov registry entry for NCT04789486 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (85% lower). The listed sponsor is Dana-Farber Cancer Institute, which has 781 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which AGuIX is the first listed.

NCT04789486 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04789486 about?

NCT04789486 is a clinical study titled "Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer". This research study is being done to help determine the safety and efficacy of gadolinium based nanoparticle, Activation and Guidance of Irradiation X (AGuIX), used in conjunction with MR-guided stereotactic body radiation therapy (SBRT) in the treatment of pancreatic cancer and lung tumors.

What is the current status of trial NCT04789486?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2021-05-27. Estimated completion is 2027-09-10.

What conditions does trial NCT04789486 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer, Advanced Pancreatic Adenocarcinoma, Unresectable Pancreatic Cancer, Ductal Adenocarcinoma of the Pancreas.

What interventions are being tested in trial NCT04789486?

The interventions under investigation include: AGuIX (DRUG), Radiotherapy (RADIATION).

Who is sponsoring clinical trial NCT04789486?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04789486 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.