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NCT00165555 · ClinicalTrials.gov registry record · Phase 1
Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma
A Phase 1 study, sponsored by Dana-Farber Cancer Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
NCT00165555: Completed Phase 1 study, sponsored by Dana-Farber Cancer Institute.
NCT00165555 is a Phase 1 study that has completed, run by Dana-Farber Cancer Institute. The registered enrollment target is 70 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00165555, a Phase 1 study, has completed, sponsored by Dana-Farber Cancer Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
The purpose of this study it to determine the safety and maximally tolerated dose (MTD) of cisplatin administered in the operating room and put into the chest and abdomen for one hour. We are also looking at the effects of heating the chemotherapy to a temperature of 42 degrees celsius.
Interventions
- DRUG Cisplatin
- DRUG Sodium Thiosulfate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 1999-08 |
| Est. Completion | 2009-11 |
| Phase | Phase 1 |
What the finished NCT00165555 record still lists
NCT00165555 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher).
The record links to 0 conditions, and to 2 interventions - of which Cisplatin is the first listed.
NCT00165555 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00165555 about?
NCT00165555 is a clinical study titled "Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma". The purpose of this study it to determine the safety and maximally tolerated dose (MTD) of cisplatin administered in the operating room and put into the chest and abdomen for one hour. We are also looking at the effects of heating the chemotherapy to a temperature of 42 degrees celsius.
What is the current status of trial NCT00165555?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 1999-08. Estimated completion is 2009-11.
What interventions are being tested in trial NCT00165555?
The interventions under investigation include: Cisplatin (DRUG), Sodium Thiosulfate (DRUG).
Who is sponsoring clinical trial NCT00165555?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00165555's enrollment target sits among peer trials
70 749th of 2000 higher than 1,227 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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