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NCT00142168 · ClinicalTrials.gov registry record · Phase 2
CC-5013 (Lenalidomide) and Rituximab in Waldenstrom's Macroglobulinemia
A Phase 2 study, sponsored by Dana-Farber Cancer Institute.
- Terminated
- Registry status
- Phase 2
- Development phase
- 16
- Enrollment target
NCT00142168: Clinical Trial Phase 2 study, sponsored by Dana-Farber Cancer Institute.
NCT00142168 is a Phase 2 study that was terminated before completion, run by Dana-Farber Cancer Institute. The registered enrollment target is 16 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00142168, a Phase 2 study, was terminated before completion, sponsored by Dana-Farber Cancer Institute.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 16 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the number of patients with Waldenstrom's macroglobulinemia that will benefit from treatment with CC-5103 (lenalidomide) and rituximab, what the side effects are and how long the benefit will last.
Primary Outcome
Time to progression is measured as the length in time in months from starting therapy until progression, defined as 25% increase in serum IgM from nadir.
Interventions
- DRUG Rituximab
- DRUG CC-5103 (lenalidomide)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2004-09 |
| Est. Completion | 2008-04 |
| Phase | Phase 2 |
Why NCT00142168 stopped before completion
NCT00142168 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 2 interventions - of which Rituximab is the first listed.
NCT00142168 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00142168 about?
NCT00142168 is a clinical study titled "CC-5013 (Lenalidomide) and Rituximab in Waldenstrom's Macroglobulinemia". The purpose of this study is to determine the number of patients with Waldenstrom's macroglobulinemia that will benefit from treatment with CC-5103 (lenalidomide) and rituximab, what the side effects are and how long the benefit will last.
What is the current status of trial NCT00142168?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2004-09. Estimated completion is 2008-04.
What interventions are being tested in trial NCT00142168?
The interventions under investigation include: Rituximab (DRUG), CC-5103 (lenalidomide) (DRUG).
Who is sponsoring clinical trial NCT00142168?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00142168's enrollment target sits among peer trials
16 1908th of 2000 higher than 82 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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