Alliance for Clinical Trials in Oncology

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Alliance for Clinical Trials in Oncology sits in the top decile of US sponsors by registered trial count (#80 of 15,742 sponsors by registered trial count).

446 total trials 29 currently recruiting 346 completed early-phase tilt top decile by trial count

Alliance for Clinical Trials in Oncology: 446 sponsored US clinical trials, 29 recruiting.

Alliance for Clinical Trials in Oncology sponsors 446 registered US clinical trials on ClinicalTrials.gov, 29 of them currently recruiting, and 346 completed. 142 of these trials are in Phase 3-4 (later-stage) and 235 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 19 trials.

Top-decile sponsor footprint

Alliance for Clinical Trials in Oncology ranks in the top decile of sponsors by registered trial count (#80 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

346 of 377 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

446 total, page 7 of 9

COMPLETED Phase 3

Gabapentin in Treating Hot Flashes in Patients With Prostate Cancer

NCT00028574

COMPLETED Phase 3

Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

NCT00030628

COMPLETED

Genetic Study of Familial Factors in Patients With Colon Cancer

NCT00055848

COMPLETED Phase 2

Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

NCT00033748

COMPLETED Phase 2

Vinorelbine in Treating Older Women With Stage IV Breast Cancer

NCT00022152

COMPLETED Phase 2

Combination Chemotherapy With or Without Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer

NCT00028925

COMPLETED Phase 2

Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT00028600

COMPLETED

Screening Tests in Detecting Colorectal Cancer

NCT00025025

COMPLETED Phase 2

Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Unresectable Kidney Cancer

NCT00027573

COMPLETED Phase 3

Surgery Versus Internal Radiation in Treating Patients With Stage II Prostate Cancer

NCT00023686

COMPLETED Phase 1

Irinotecan in Treating Aging Patients With Solid Tumors

NCT00026195

COMPLETED Phase 3

Comparison of Combination Chemotherapy Regimens in Treating Older Women Who Have Undergone Surgery for Breast Cancer

NCT00024102

COMPLETED Phase 2

Combination Chemotherapy and Radiation Therapy in Treating Patients With Pancreatic Cancer

NCT00026130

COMPLETED Phase 2

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Pancreatic Cancer

NCT00026403

COMPLETED Phase 2

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

NCT00033696

COMPLETED Phase 2

Gemcitabine Plus Docetaxel in Treating Patients With Unresectable or Metastatic Liver Cancer

NCT00006010

COMPLETED Phase 2

Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT00022646

COMPLETED Phase 2

Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

NCT00005850

COMPLETED Phase 3

Shark Cartilage in Treating Patients With Advanced Colorectal or Breast Cancer

NCT00026117

COMPLETED Phase 2

Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma

NCT00017186

COMPLETED Phase 2

Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer

NCT00023751

COMPLETED Phase 2

Chemotherapy and Rituximab With Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma

NCT00020943

COMPLETED Phase 2

Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer

NCT00016913

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

NCT00009893

COMPLETED Phase 2

ICI 182780 in Treating Women With Metastatic Breast Cancer

NCT00012025

COMPLETED Phase 2

Vinorelbine in Treating Older Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

NCT00008333

COMPLETED Phase 2

Irinotecan or Fluorouracil Plus Leucovorin in Treating Patients With Previously Treated Metastatic Colorectal Cancer

NCT00016952

COMPLETED Phase 2

Karenitecin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer

NCT00010218

COMPLETED Phase 2

Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT00006265

COMPLETED Phase 1

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

NCT00006012

COMPLETED Phase 3

Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer

NCT00006349

COMPLETED Phase 2

Gemcitabine and ISIS 2503 in Treating Patients With Advanced or Metastatic Cancer of the Pancreas

NCT00006467

COMPLETED Phase 2

Ceramide Cream in Treating Women With Cutaneous Breast Cancer

NCT00008320

COMPLETED Phase 2

Gemcitabine Alone or in Combination With Other Chemotherapy Drugs in Treating Patients With Metastatic Cancer of the Pancreas

NCT00012220

COMPLETED Phase 2

LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer

NCT00006007

COMPLETED Phase 1

Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer And Lung Dysfunction

NCT00009789

COMPLETED Phase 2

Green Tea Extract in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

NCT00005828

COMPLETED Phase 2

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma

NCT00006747

COMPLETED Phase 2

Docetaxel and Carboplatin in Treating Women With Metastatic Breast Cancer

NCT00005963

COMPLETED Phase 2

Capecitabine in Treating Patients With Malignant Mesothelioma

NCT00004183

COMPLETED Phase 2

Combination Chemotherapy Plus Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma

NCT00005601

COMPLETED Phase 3

Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment

NCT00006348

COMPLETED Phase 2

Sargramostim in Treating Patients With Kidney Cancer That Has Spread to the Lung

NCT00006483

COMPLETED

Gene Expression Profiling and Genetic Analysis of Tissues From Patients With Breast Cancer

NCT00899509

COMPLETED Phase 2

Androgen Suppression Plus Radiation Therapy in Treating Patients With Prostate Cancer

NCT00006359

COMPLETED Phase 2

Study of Aerosolized Sargramostim in Treating Patients With Melanoma Metastatic to the Lung

NCT00005610

COMPLETED Phase 2

Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate

NCT00006214

COMPLETED Phase 1

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

NCT00006029

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma

NCT00006125

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer

NCT00005972

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What is open in the Alliance for Clinical Trials in Oncology pipeline

29 recruiting of 446 indexed (7% open); 346 completed (78%).

Phase mix: 142 late (III/IV) vs 235 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Alliance for Clinical Trials in Oncology: open-pipeline peers nationwide

Peers matched on 446 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

Alliance for Clinical Trials in Oncology sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 5%10%15%20%25% Total trials Recruiting share Alliance for Clinical Trials in OncologyMedical College of WisconsinUniversity of VirginiaChildren's Hospital of PhiladelphiaNovo Nordisk A/SNational Institutes of Health Clinical Center (CC)Insmed IncorporatedNICHD Neonatal Research NetworkHennepin Healthcare Research Institute
Alliance for Clinical Trials in Oncology sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Alliance for Clinical Trials in Oncology sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 446 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this Alliance for Clinical Trials in Oncology page

446 registered trials is a research-attention snapshot, not an endorsement of Alliance for Clinical Trials in Oncology or any single study.

  • 29 of Alliance for Clinical Trials in Oncology's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Alliance for Clinical Trials in Oncology studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Alliance for Clinical Trials in Oncology pipeline card: 446 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.