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NCT02303990 · ClinicalTrials.gov registry record · Phase 1

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

A Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.

Completed
Registry status
Phase 1
Development phase
59
Enrollment target

NCT02303990 is a Phase 1 study that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 59 participants.

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The verdict

NCT02303990, a Phase 1 study, has completed, sponsored by Abramson Cancer Center at Penn Medicine.

COMPLETED
Registry status
Phase 1
Development phase
59 participants
Enrollment target

Study Summary

Phase I clinical trial of hypofractionated radiotherapy to an isolated index lesion in combination with the PD-1 inhibitor, Pembrolizumab in patients with metastatic cancers who have failed anti-PD-1 therapy (melanoma and NSCLC) and patients with metastatic cancers who have have progressed after at least one regimen of systemic therapy (breast, pancreas, and other).

Interventions

  • DRUG Pembrolizumab
  • RADIATION Radiotherapy

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2015-01-08
Est. Completion 2019-12-31
Phase Phase 1

What the Registry Record Tells You About NCT02303990

The ClinicalTrials.gov registry entry for NCT02303990 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 59 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abramson Cancer Center at Penn Medicine, which has 402 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT02303990 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02303990 about?

NCT02303990 is a clinical study titled "RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers". Phase I clinical trial of hypofractionated radiotherapy to an isolated index lesion in combination with the PD-1 inhibitor, Pembrolizumab in patients with metastatic cancers who have failed anti-PD-1 therapy (melanoma and NSCLC) and patients with metastatic cancers who have have progressed after at ...

What is the current status of trial NCT02303990?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 59 participants. The study started on 2015-01-08. Estimated completion is 2019-12-31.

What interventions are being tested in trial NCT02303990?

The interventions under investigation include: Pembrolizumab (DRUG), Radiotherapy (RADIATION).

Who is sponsoring clinical trial NCT02303990?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.