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ClinicalTrials.gov 6 recruiting now early-phase tilt

Urinary Bladder Neoplasms: early-phase trial registry

6 of 20 indexed Urinary Bladder Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 6 currently recruiting · #848 of 28,707 conditions by registered trial count

Urinary Bladder Neoplasms: 20 US clinical trials tracked, 6 recruiting.

Urinary Bladder Neoplasms is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 4 of these trials.

Enrollment posture brief

Registry condition urinary-bladder-neoplasms

OPEN 6 | RECR 30% | LATE 5 | EARLY 15 | RANK #848 | SPON 4

Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)

Advanced or Metastatic Solid55%ALS50%Urinary Bladder Neoplasm (th…30%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Urinary Bladder Neoplasms

Urinary Bladder Neoplasms lists 6 open slots (30% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Urinary Bladder Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Urinary Bladder Neoplasms is recruiting below its size-band peers.

    6 of 20 indexed trials (30%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Urinary Bladder Neoplasms research.

    Janssen Research & Development accounts for 4 of 20 trials (20%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Urinary Bladder Neoplasms enrolment sits around 220 participants.

    Median target enrolment is 220 among the 20 trials that report a genuine target (sentinel values excluded). 6 of those (30%) plan for fewer than 100 participants.

  4. Urinary Bladder Neoplasms research is mostly interventional.

    20 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 29Phase 35

Open and recent trials

20 total, page 1 of 1

RECRUITING Phase 1 1,006 participants

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT04389632

RECRUITING Phase 1 535 participants

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Eli Lilly and Company

NCT05614739

RECRUITING Phase 3 450 participants

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Eli Lilly and Company

NCT07218380

RECRUITING Phase 2 308 participants

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Merck Sharp & Dohme

NCT06833073

RECRUITING Phase 1 45 participants

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

Merck Sharp & Dohme

NCT07222488

RECRUITING Early Phase 1 42 participants

Virtual Histology of the Bladder Wall for Bladder Cancer Staging

Jodi Maranchie

NCT04369560

ACTIVE NOT RECRUITING Phase 3 855 participants

A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

Bristol-Myers Squibb

NCT03661320

ACTIVE NOT RECRUITING Phase 3 520 participants

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Merck Sharp & Dohme

NCT04241185

ACTIVE NOT RECRUITING Phase 3 518 participants

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Janssen Research & Development

NCT04658862

ACTIVE NOT RECRUITING Phase 1 348 participants

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Astellas Pharma Global Development

NCT03288545

ACTIVE NOT RECRUITING Phase 2 220 participants

A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

Janssen Research & Development

NCT04640623

ACTIVE NOT RECRUITING Phase 2 163 participants

A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder

Janssen Research & Development

NCT04919512

ACTIVE NOT RECRUITING Phase 2 154 participants

A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU)

AstraZeneca

NCT03459846

COMPLETED Phase 3 337 participants

Larotaxel + Cisplatin Versus Gemcitabine + Cisplatin in First Line Treatment of Locally Advanced/Metastatic Urothelial Tract or Bladder Cancer

Sanofi

NCT00625664

COMPLETED Phase 2 219 participants

A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer

Astellas Pharma

NCT03219333

COMPLETED Phase 2 107 participants

A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

Janssen Research & Development

NCT04172675

COMPLETED Phase 2 69 participants

Cabozantinib for Advanced Urothelial Cancer

National Cancer Institute (NCI)

NCT01688999

COMPLETED Phase 2 28 participants

Tamoxifen for Progressive Transitional Cell Carcinoma Following Previous Chemotherapy Treatment

Seth Lerner

NCT00710970

COMPLETED Phase 1 15 participants

Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Lipac Oncology

NCT03081858

COMPLETED Phase 2 8 participants

Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

National Cancer Institute (NCI)

NCT02788201

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 9
Phase 3 5

Named interventions

Most-linked intervention names on Urinary Bladder Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cetrelimab Biological
3 trials
TAR-200 Drug
3 trials
cisplatin Drug
3 trials
Cisplatin Drug
3 trials
Pembrolizumab Drug
3 trials
gemcitabine Drug
2 trials
carboplatin Drug
2 trials
Gemcitabine Drug
2 trials

US sites by state

Facility locations filed on Urinary Bladder Neoplasms trials. A trial with sites in several states counts in each.

California 14 trials
Florida 12 trials
Colorado 10 trials
Arizona 10 trials
Illinois 9 trials
New York 8 trials
Maryland 7 trials
Pennsylvania 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Urinary Bladder Neoplasms page

20 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Urinary Bladder Neoplasms condition card totals 20 registered trials; most-linked intervention Cetrelimab; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.