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ClinicalTrials.gov 6 recruiting now official registry

Urinary Bladder Neoplasms clinical trials

6 of 20 indexed Urinary Bladder Neoplasms trials are currently recruiting.

20 US clinical trials · 6 currently recruiting

Urinary Bladder Neoplasms is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 4 of these trials.

The research picture

Urinary Bladder Neoplasms has 20 registered US clinical trials, 6 of them open to new participants right now, about 30% of the total.

6
recruiting participants now
30%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
4
top sponsor: Janssen Research & Development
Phase 16Phase 29Phase 35

Active & Recent Trials

20 total, page 1 of 1

RECRUITING Phase 1 1,006 participants

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT04389632

RECRUITING Phase 1 535 participants

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Eli Lilly and Company

NCT05614739

RECRUITING Phase 3 450 participants

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Eli Lilly and Company

NCT07218380

RECRUITING Phase 2 308 participants

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Merck Sharp & Dohme

NCT06833073

RECRUITING Phase 1 45 participants

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

Merck Sharp & Dohme

NCT07222488

RECRUITING Early Phase 1 42 participants

Virtual Histology of the Bladder Wall for Bladder Cancer Staging

Jodi Maranchie

NCT04369560

ACTIVE NOT RECRUITING Phase 3 855 participants

A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

Bristol-Myers Squibb

NCT03661320

ACTIVE NOT RECRUITING Phase 3 520 participants

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Merck Sharp & Dohme

NCT04241185

ACTIVE NOT RECRUITING Phase 3 518 participants

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Janssen Research & Development

NCT04658862

ACTIVE NOT RECRUITING Phase 1 348 participants

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Astellas Pharma Global Development

NCT03288545

ACTIVE NOT RECRUITING Phase 2 220 participants

A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

Janssen Research & Development

NCT04640623

ACTIVE NOT RECRUITING Phase 2 163 participants

A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder

Janssen Research & Development

NCT04919512

ACTIVE NOT RECRUITING Phase 2 154 participants

A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU)

AstraZeneca

NCT03459846

COMPLETED Phase 3 337 participants

Larotaxel + Cisplatin Versus Gemcitabine + Cisplatin in First Line Treatment of Locally Advanced/Metastatic Urothelial Tract or Bladder Cancer

Sanofi

NCT00625664

COMPLETED Phase 2 219 participants

A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer

Astellas Pharma

NCT03219333

COMPLETED Phase 2 107 participants

A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

Janssen Research & Development

NCT04172675

COMPLETED Phase 2 69 participants

Cabozantinib for Advanced Urothelial Cancer

National Cancer Institute (NCI)

NCT01688999

COMPLETED Phase 2 28 participants

Tamoxifen for Progressive Transitional Cell Carcinoma Following Previous Chemotherapy Treatment

Seth Lerner

NCT00710970

COMPLETED Phase 1 15 participants

Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Lipac Oncology

NCT03081858

COMPLETED Phase 2 8 participants

Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

National Cancer Institute (NCI)

NCT02788201

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 9
Phase 3 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Urinary Bladder Neoplasms Trial Landscape

20 indexed Urinary Bladder Neoplasms studies · 6 recruiting (30%).

Phase mix: 5 late (III/IV) vs 15 early (I/II).

Top sponsor: Janssen Research & Development (4 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Urinary Bladder Neoplasms?

PlainTrial tracks 20 US clinical trials for Urinary Bladder Neoplasms, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Urinary Bladder Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.