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Ulcerative Colitis clinical trials
45 of 123 indexed Ulcerative Colitis trials are currently recruiting.
123 US clinical trials · 45 currently recruiting
Ulcerative Colitis is the subject of 123 registered US clinical trials on ClinicalTrials.gov, 45 of them currently open to new participants. 32 are in Phase 3-4 (later-stage) and 47 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 9 of these trials.
The research picture
Ulcerative Colitis has 123 registered US clinical trials, 45 of them open to new participants right now, about 37% of the total.
- 45
- recruiting participants now
- 37%
- of trials open to enrollment
- 32
- in Phase 3–4 (later-stage)
- 9
- top sponsor: Eli Lilly and Company
Active & Recent Trials
123 total, page 3 of 3
Long-term Safety With Vedolizumab Intravenous (IV) in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Takeda
NCT03196427
A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease
University of Washington
NCT05651542
Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis
Mayo Clinic
NCT06316999
Ulcerative Colitis Relapse Prevention Trial, Hypnosis
Northwestern University
NCT00798642
Mind/Body Medicine and IBD Flare-Up
Rush University Medical Center
NCT00568256
A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of rhuMAb Beta7 in Patients With Ulcerative Colitis
Genentech
NCT00694980
SMART-IBD App Trial
Children's Hospital Medical Center, Cincinnati
NCT06023667
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181.
Amgen
NCT01290042
Safety, Tolerability, and Pharmacokinetics of Oral NX-13 in Active Ulcerative Colitis
Landos Biopharma
NCT04862741
Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis
Bridge Biotherapeutics
NCT04596293
Evaluation of an Oral Anti-TNF Antibody in Patients With Active Ulcerative Colitis
Avaxia Biologics, Incorporated
NCT01759056
Protein Metabolism in Newly Diagnosed Pediatric Inflammatory Bowel Disease
Indiana University
NCT00586352
Transcutaneous VNS to Treat Pediatric IBD
Northwell Health
NCT03863704
Digital Behavioral Interventions in Inflammatory Bowel Disease
Montefiore Medical Center
NCT04861597
Safety and Pharmacokinetics Study of HE3286 in Patients With Active, Mild-to-Moderate Ulcerative Colitis
Harbor Therapeutics
NCT00628433
A Study of Mirikizumab (LY3074828) in Children and Teenagers With Ulcerative Colitis (UC)
Eli Lilly and Company
NCT04004611
Fecal Transplant for Ulcerative Colitis
University of Minnesota
NCT03948919
A Dose-Escalation Study of MDX-1100 in Patients With Active Ulcerative Colitis
Bristol-Myers Squibb
NCT00295282
Broccoli Sprouts for Mild Ulcerative Colitis
University of Michigan
NCT05507931
Anti-Inflammatory Effects of Mango Polyphenolics in Inflammatory Bowel Disease
Texas A&M University
NCT02227602
Interferon-beta1a (AVONEX) Treatment of Ulcerative Colitis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00048347
Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis
Stacy A. Kahn
NCT02330653
Oral OKT3 for the Treatment of Active Ulcerative Colitis
Brigham and Women's Hospital
NCT01287195
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 15 |
| Phase 2 | 32 |
| Phase 3 | 28 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Ulcerative Colitis Trial Landscape
123 indexed Ulcerative Colitis studies · 45 recruiting (37%).
Phase mix: 32 late (III/IV) vs 47 early (I/II).
Top sponsor: Eli Lilly and Company (9 trials), 9 others listed. 23 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Ulcerative Colitis?
PlainTrial tracks 123 US clinical trials for Ulcerative Colitis, of which 45 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Ulcerative Colitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.