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Type 2 Diabetes Mellitus (T2DM): early-phase trial registry
20 of 25 indexed Type 2 Diabetes Mellitus (T2DM) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #652 of 28,707 conditions by registered trial count.
25 US clinical trials · 20 currently recruiting · #652 of 28,707 conditions by registered trial count
Type 2 Diabetes Mellitus (T2DM): 25 US clinical trials tracked, 20 recruiting.
Type 2 Diabetes Mellitus (T2DM) is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Alnylam Pharmaceuticals, running 2 of these trials.
Enrollment posture brief
Registry condition type-2-diabetes-mellitus-t2dm
OPEN 20 | RECR 80% | LATE 2 | EARLY 8 | RANK #652 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Ablation (80% recruiting · 5 trials)
Type 2 Diabetes Mellitus (T2DM) lists 20 open slots (80% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes Mellitus (T2DM) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes Mellitus (T2DM) is recruiting above its size-band peers.
20 of 25 indexed trials (80%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes Mellitus (T2DM) trials is spread across many organizations.
Alnylam Pharmaceuticals accounts for 2 of 25 trials (8%). 22 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes Mellitus (T2DM) enrolment sits around 144 participants.
Median target enrolment is 144 among the 25 trials that report a genuine target (sentinel values excluded). 11 of those (44%) plan for fewer than 100 participants.
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Type 2 Diabetes Mellitus (T2DM) research is mostly interventional.
23 interventional and 2 observational studies make up this index (92% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
25 total, page 1 of 1
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
Clindove Research
NCT07106879
Achieving Routine Intervention and Screening for Emotional Health
University of Chicago
NCT06887049
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
Duke University
NCT06906627
CGM for Management of Type 2 Diabetes in Pregnancy
University of Alabama at Birmingham
NCT06628453
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
Duke University
NCT06906640
The GRoceries Aimed at Increasing Nutrition Study
University of Pennsylvania
NCT07167004
Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED
Rutgers, The State University of New Jersey
NCT06899191
Human Immunodeficiency Virus (HIV) Food Insecurities
Wake Forest University Health Sciences
NCT04943861
Low-Dose Pioglitazone in Patients With NASH (AIM 2)
University of Florida
NCT04501406
RCT Glargine vs NPH for Treatment of DM in Pregnancy
Loyola University
NCT06619301
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Alnylam Pharmaceuticals
NCT06845202
Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes
Johns Hopkins University
NCT06921356
CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes
Thomas Jefferson University
NCT07184775
Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge
Vanderbilt University Medical Center
NCT06852950
Diabetes Management Using Continuous Glucose Monitors and Remote Patient Monitoring in Underserved Populations
Diabetes Solutions International
NCT06939413
Continuous Glucose Monitoring for Self-Management of Type 2 Diabetes in Young Adults
San Diego State University
NCT07065721
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Alnylam Pharmaceuticals
NCT07465224
Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D
University of Colorado, Denver
NCT07005362
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
Estar Medical dba Medical Technologies
NCT06810726
Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes
Stanford University
NCT06836479
A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
Amgen
NCT06660173
A Study of CT-388 in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus
Carmot Therapeutics
NCT06628362
A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM
Metsera, a wholly owned subsidiary of Pfizer
NCT06897202
Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation
HiDO Technologies
NCT06691256
Impact of Chronic Kidney Disease on Clopidogrel Effects in Diabetes Mellitus
University of Florida
NCT03774394
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 7 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 2 Diabetes Mellitus (T2DM) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 2 Diabetes Mellitus (T2DM) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 2 Diabetes Mellitus (T2DM) page
25 registered trials, 20 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 20 Type 2 Diabetes Mellitus (T2DM) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Alnylam Pharmaceuticals sponsors the most Type 2 Diabetes Mellitus (T2DM) trials on record, review their full trial history before evaluating a specific study. See Alnylam Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 2 Diabetes Mellitus (T2DM) condition card totals 25 registered trials; most-linked intervention Placebo; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.