Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Type 2 Diabetes Mellitus (T2DM)
Open-data reference.
25 US clinical trials · 20 currently recruiting
Active & Recent Trials
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
Clindove Research
NCT07106879
Achieving Routine Intervention and Screening for Emotional Health
University of Chicago
NCT06887049
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
Duke University
NCT06906627
CGM for Management of Type 2 Diabetes in Pregnancy
University of Alabama at Birmingham
NCT06628453
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
Duke University
NCT06906640
The GRoceries Aimed at Increasing Nutrition Study
University of Pennsylvania
NCT07167004
Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED
Rutgers, The State University of New Jersey
NCT06899191
Human Immunodeficiency Virus (HIV) Food Insecurities
Wake Forest University Health Sciences
NCT04943861
Low-Dose Pioglitazone in Patients With NASH (AIM 2)
University of Florida
NCT04501406
RCT Glargine vs NPH for Treatment of DM in Pregnancy
Loyola University
NCT06619301
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Alnylam Pharmaceuticals
NCT06845202
Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes
Johns Hopkins University
NCT06921356
CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes
Thomas Jefferson University
NCT07184775
Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge
Vanderbilt University Medical Center
NCT06852950
Diabetes Management Using Continuous Glucose Monitors and Remote Patient Monitoring in Underserved Populations
Diabetes Solutions International
NCT06939413
Continuous Glucose Monitoring for Self-Management of Type 2 Diabetes in Young Adults
San Diego State University
NCT07065721
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Alnylam Pharmaceuticals
NCT07465224
Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D
University of Colorado, Denver
NCT07005362
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
Estar Medical dba Medical Technologies
NCT06810726
Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes
Stanford University
NCT06836479
A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
Amgen
NCT06660173
A Study of CT-388 in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus
Carmot Therapeutics
NCT06628362
A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM
Metsera, a wholly owned subsidiary of Pfizer
NCT06897202
Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation
HiDO Technologies
NCT06691256
Impact of Chronic Kidney Disease on Clopidogrel Effects in Diabetes Mellitus
University of Florida
NCT03774394
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 7 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Type 2 Diabetes Mellitus (T2DM) Trial Landscape
ClinicalTrials.gov lists 25 US studies indexed under Type 2 Diabetes Mellitus (T2DM), and 20 of those are currently open to recruitment — roughly 80% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Type 2 Diabetes Mellitus (T2DM) shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Type 2 Diabetes Mellitus (T2DM) is led by Alnylam Pharmaceuticals with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Type 2 Diabetes Mellitus (T2DM)?
PlainTrial tracks 25 US clinical trials for Type 2 Diabetes Mellitus (T2DM), of which 20 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Type 2 Diabetes Mellitus (T2DM)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.