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A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
NCT06660173 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study is to assess the dose-response relationship of maridebart cafraglutide on glucose control compared with placebo.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Maridebart Cafraglutide
Study Locations (20)
California
- Anaheim Clinical Trials — Anaheim
- Hope Clinical Research LLC — Canoga Park
- Orange County Research Center — Lake Forest
- San Jose Clinical Trials — San Jose
Florida
- Northeast Research Institute - Neri — Fleming Island
- New Horizon Research Center — Miami
- Florida Institute for Clinical Research — Orlando
- Conquest Research - Winter Park — Winter Park
Texas
- FutureSearch Trials of Neurology — Austin
- Velocity Clinical Research - Dallas — Dallas
Alabama
- Accel Research Site - Birmingham Clinical Research Unit — Birmingham
Georgia
- Accel Research Site - Neurostudies — Decatur
Illinois
- Cedar Crosse Research and Health Care — Chicago
Louisiana
- Tandem Clinical Research - Marrero — Marrero
Michigan
- DM Clinical - Detroit — Southfield
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 409 participants |
| Start Date | 2024-11-07 |
| Est. Completion | 2026-11-10 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06660173
The ClinicalTrials.gov registry entry for NCT06660173 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 409 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 266 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Type 2 Diabetes Mellitus (T2DM) appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06660173 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Florida, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06660173 about?
NCT06660173 is a clinical study titled "A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)". The main purpose of this study is to assess the dose-response relationship of maridebart cafraglutide on glucose control compared with placebo.
What is the current status of trial NCT06660173?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 409 participants. The study started on 2024-11-07. Estimated completion is 2026-11-10.
What conditions does trial NCT06660173 study?
This clinical trial studies the following conditions: Type 2 Diabetes Mellitus (T2DM). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06660173?
The interventions under investigation include: Placebo (DRUG), Maridebart Cafraglutide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06660173?
This trial is sponsored by Amgen, which has 266 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06660173 being conducted?
This trial has 20 study locations across Alabama, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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