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ClinicalTrials.gov 2 recruiting now official registry

Total Hip Arthroplasty clinical trials

2 of 13 indexed Total Hip Arthroplasty trials are currently recruiting.

13 US clinical trials · 2 currently recruiting

Total Hip Arthroplasty is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Zimmer Biomet, running 2 of these trials.

The research picture

Total Hip Arthroplasty has 13 registered US clinical trials, 2 of them open to new participants right now, about 15% of the total.

2
recruiting participants now
15%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Zimmer Biomet
Phase 21Phase 31Phase 41

Active & Recent Trials

13 total, page 1 of 1

RECRUITING NA 300 participants

G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study

Zimmer Biomet

NCT04754087

RECRUITING Phase 3 162 participants

Methadone in THA for Post-op Pain and Opioid Reduction

Medical University of South Carolina

NCT07227064

ACTIVE NOT RECRUITING NA 163 participants

Patient Utilization of Opioid Destruction Bags in the Post-op Period

University of Nebraska

NCT05875857

COMPLETED NA 388 participants

RCT Foley Catheter Study for Elective TJA

Rush University Medical Center

NCT05428020

COMPLETED Phase 4 165 participants

Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular

Mayo Clinic

NCT02242201

COMPLETED NA 95 participants

Improving Rehabilitation Outcomes After Total Hip Arthroplasty

VA Office of Research and Development

NCT02920866

COMPLETED 83 participants

Continuum™ Metal Bearing System in Total Hip Arthroplasty

Zimmer Biomet

NCT03382652

COMPLETED NA 82 participants

Anterior Capsulectomy vs. Repair in Direct Anterior THA

OrthoCarolina Research Institute

NCT01621932

COMPLETED Phase 2 80 participants

Quadratus Lumborum Block Versus Control for Total Hip Arthroplasty

University of Alabama at Birmingham

NCT03408483

COMPLETED NA 68 participants

Strength and Function Following Total Hip Arthroplasty

University of Colorado, Denver

NCT01817010

COMPLETED NA 60 participants

Continuous L2 Paravertebral Block Versus Continuous Lumbar Plexus Block for Postoperative Analgesia

University of Pittsburgh

NCT01571492

COMPLETED NA 50 participants

The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery

Thomas Jefferson University

NCT03897621

COMPLETED NA 44 participants

Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty

Wake Forest University Health Sciences

NCT03409900

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Total Hip Arthroplasty Trial Landscape

13 indexed Total Hip Arthroplasty studies · 2 recruiting (15%).

Phase mix: 2 late (III/IV) vs 1 early (I/II).

Top sponsor: Zimmer Biomet (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Total Hip Arthroplasty?

PlainTrial tracks 13 US clinical trials for Total Hip Arthroplasty, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Total Hip Arthroplasty?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.