OrthoCarolina Research Institute

Closed portfolio with a later-stage archive tilt

According to ClinicalTrials.gov-derived indexes, OrthoCarolina Research Institute sits in the top decile of US sponsors by registered trial count (#568 of 15,742 sponsors by registered trial count).

28 total trials none currently recruiting 18 completed later-stage tilt top decile by trial count

OrthoCarolina Research Institute: 28 sponsored US clinical trials, none currently recruiting.

OrthoCarolina Research Institute sponsors 28 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 18 completed. 14 of these trials are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hallux Rigidus, with 1 trials.

Top-decile sponsor footprint

OrthoCarolina Research Institute ranks in the top decile of sponsors by registered trial count (#568 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 27/100

18 of 24 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (75.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

28 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 2

Adductor Canal Block

NCT04513145

ACTIVE NOT RECRUITING NA

One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection

NCT02734134

ACTIVE NOT RECRUITING NA

Lymphedema Following Hand/Wrist Surgery in Women Post Axillary Node Dissection

NCT00984269

NOT YET RECRUITING Phase 4

Mochida ReFeel for Digital Nerve Injuries

NCT07524465

TERMINATED NA

Tourniquet Use in Anterior Cruciate Ligament Repair

NCT05931627

TERMINATED NA

Cemented vs. Cementless TKA

NCT04597684

COMPLETED NA

Opioid-Free Orthopaedic Surgery

NCT04176783

COMPLETED Phase 4

Opioid-Free Shoulder Arthroplasty

NCT03540030

COMPLETED NA

Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint

NCT02795247

COMPLETED Phase 4

Betamethasone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosynovitis

NCT02604537

TERMINATED Phase 4

Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study

NCT02202369

COMPLETED Phase 4

Liposomal Bupivacaine in Simultaneous Bilateral Total Knee Arthroplasty

NCT02349542

TERMINATED

Acetabular Bone Vascularity in Metal-on-Metal Revisions

NCT02239406

COMPLETED

Serum Levels of Bupivacaine in Autotransfusion Drains Following Total Joint Arthroplasty

NCT02276040

TERMINATED

A Validated Necrosis Assay to Determine the Need for Revision Surgery in Metal-on-metal Total Hip Arthroplasty

NCT02208271

COMPLETED Phase 4

Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain

NCT02226159

COMPLETED Phase 4

Foot and Ankle Clinic Application for Liposomal Related Anesthetic

NCT02586077

COMPLETED Phase 4

Amniotic Membrane as an Adjunct Treatment for Hallux Rigidus

NCT01825356

COMPLETED NA

Reverse Shoulder Arthroplasty With or Without Concomitant Latissimus and Teres Major Transfer for Shoulder Pseudoparalysis With Teres Minor Dysfunction

NCT01697865

COMPLETED Phase 4

Reinfusion Drains vs Tranexamic Acid in Total Joint Arthroplasty

NCT01636414

COMPLETED NA

Anterior Capsulectomy vs. Repair in Direct Anterior THA

NCT01621932

COMPLETED Phase 4

Anatomic Reconstruction of the Patellofemoral Joint

NCT01375231

COMPLETED Phase 4

Ankle Block Versus Popliteal Fossa Block as Primary Anesthesia for Forefoot Surgical Procedures

NCT01376960

COMPLETED Phase 4

Efficacy and Satisfaction Comparing Two Braces in the Treatment of Developmental Dysplasia of the Hip (DDH) in Infants

NCT01375218

COMPLETED NA

Efficacy and Patient Satisfaction With AQUACEL® Ag Surgical Dressing Compared to Standard Surgical Dressing

NCT01258270

COMPLETED NA

A Trial Comparing Mini-posterior Approach and Direct Anterior Approach

NCT01024309

COMPLETED Phase 4

Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer

NCT00950053

TERMINATED Phase 4

Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures

NCT00950183

How the OrthoCarolina Research Institute archive is shaped

28 indexed studies, none listed as recruiting (0% open); 18 completed (64%).

Phase mix: 14 late (III/IV) vs 1 early (I/II) (later-stage heavy).

Top condition: Hallux Rigidus (1 trial), 9 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

OrthoCarolina Research Institute: archived-pipeline peers nationwide

Peers matched on 28 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

OrthoCarolina Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0102030 0%5%10%15%20%25% Total trials Recruiting share OrthoCarolina Research InstituteAxsome TherapeuticsBenaroya Research InstituteCAMC Health SystemCTI BioPharma10xBio22nd Century Group23andMe3-C Institute for Social Development
OrthoCarolina Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

OrthoCarolina Research Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 28 archived trials

Sponsors with similar archive density (± trial count)

What to do with this OrthoCarolina Research Institute page

28 registered trials is a research-attention snapshot, not an endorsement of OrthoCarolina Research Institute or any single study.

  • None of OrthoCarolina Research Institute's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Hallux Rigidus is the condition OrthoCarolina Research Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hallux Rigidus trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

OrthoCarolina Research Institute pipeline card: 28 registered trials from official public datasets.Report a data error.