OrthoCarolina Research Institute

28 total trials 18 completed

OrthoCarolina Research Institute sponsors 28 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 18 completed. 14 of these trials are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hallux Rigidus, with 1 trials.

Trial Pipeline

28 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 2

Adductor Canal Block

NCT04513145

ACTIVE NOT RECRUITING NA

One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection

NCT02734134

ACTIVE NOT RECRUITING NA

Lymphedema Following Hand/Wrist Surgery in Women Post Axillary Node Dissection

NCT00984269

NOT YET RECRUITING Phase 4

Mochida ReFeel for Digital Nerve Injuries

NCT07524465

TERMINATED NA

Tourniquet Use in Anterior Cruciate Ligament Repair

NCT05931627

TERMINATED NA

Cemented vs. Cementless TKA

NCT04597684

COMPLETED NA

Opioid-Free Orthopaedic Surgery

NCT04176783

COMPLETED Phase 4

Opioid-Free Shoulder Arthroplasty

NCT03540030

COMPLETED NA

Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint

NCT02795247

COMPLETED Phase 4

Betamethasone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosynovitis

NCT02604537

TERMINATED Phase 4

Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study

NCT02202369

COMPLETED Phase 4

Liposomal Bupivacaine in Simultaneous Bilateral Total Knee Arthroplasty

NCT02349542

TERMINATED

Acetabular Bone Vascularity in Metal-on-Metal Revisions

NCT02239406

COMPLETED

Serum Levels of Bupivacaine in Autotransfusion Drains Following Total Joint Arthroplasty

NCT02276040

TERMINATED

A Validated Necrosis Assay to Determine the Need for Revision Surgery in Metal-on-metal Total Hip Arthroplasty

NCT02208271

COMPLETED Phase 4

Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain

NCT02226159

COMPLETED Phase 4

Foot and Ankle Clinic Application for Liposomal Related Anesthetic

NCT02586077

COMPLETED Phase 4

Amniotic Membrane as an Adjunct Treatment for Hallux Rigidus

NCT01825356

COMPLETED NA

Reverse Shoulder Arthroplasty With or Without Concomitant Latissimus and Teres Major Transfer for Shoulder Pseudoparalysis With Teres Minor Dysfunction

NCT01697865

COMPLETED Phase 4

Reinfusion Drains vs Tranexamic Acid in Total Joint Arthroplasty

NCT01636414

COMPLETED NA

Anterior Capsulectomy vs. Repair in Direct Anterior THA

NCT01621932

COMPLETED Phase 4

Anatomic Reconstruction of the Patellofemoral Joint

NCT01375231

COMPLETED Phase 4

Ankle Block Versus Popliteal Fossa Block as Primary Anesthesia for Forefoot Surgical Procedures

NCT01376960

COMPLETED Phase 4

Efficacy and Satisfaction Comparing Two Braces in the Treatment of Developmental Dysplasia of the Hip (DDH) in Infants

NCT01375218

COMPLETED NA

Efficacy and Patient Satisfaction With AQUACEL® Ag Surgical Dressing Compared to Standard Surgical Dressing

NCT01258270

COMPLETED NA

A Trial Comparing Mini-posterior Approach and Direct Anterior Approach

NCT01024309

COMPLETED Phase 4

Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer

NCT00950053

TERMINATED Phase 4

Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures

NCT00950183

What the Pipeline for OrthoCarolina Research Institute Shows

According to the ClinicalTrials.gov registry, OrthoCarolina Research Institute is linked to 28 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 18 are already marked complete, representing roughly 64% of the total.

The phase mix for OrthoCarolina Research Institute reports 14 late-stage studies (Phase 3 and Phase 4 combined) and 1 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for OrthoCarolina Research Institute is Hallux Rigidus with 1 linked trial, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.