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2026 data Public-data reference. official source

Tibial Fractures

Open-data reference.

13 US clinical trials · 8 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 1,000 participants

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

Major Extremity Trauma Research Consortium

NCT07006675

RECRUITING Phase 3 497 participants

Intramedullary Calcium Sulfate Antibiotic Depot

Wake Forest University Health Sciences

NCT05766670

RECRUITING Phase 4 484 participants

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Wake Forest University Health Sciences

NCT05421741

RECRUITING NA 130 participants

Intramedullary Bone Grafting for Open Tibial Shaft Fractures

University of Louisville

NCT03891888

RECRUITING NA 100 participants

Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

University of Alabama at Birmingham

NCT06679049

RECRUITING NA 60 participants

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

Major Extremity Trauma Research Consortium

NCT05889559

RECRUITING NA 40 participants

Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?

United States Naval Medical Center, San Diego

NCT05652881

RECRUITING NA 40 participants

Blood Flow Restriction Training in Patients With Lower Extremity Fractures

Denver Health and Hospital Authority

NCT06496035

ACTIVE NOT RECRUITING 1,500 participants

Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®

AO Innovation Translation Center

NCT04113044

COMPLETED 103 participants

A Post-Market Clinical Evaluation of the Treatment of Tibia Fractures With the T2 Alpha Tibia Nailing System

Stryker Trauma and Extremities

NCT04015167

COMPLETED NA 66 participants

Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture

Brian W. Noehren

NCT05274022

COMPLETED NA 40 participants

Suprapatellar Versus Infrapatellar Nailing in Tibial Fractures: A Pilot Study

Florida Orthopaedic Institute

NCT01341418

COMPLETED NA 21 participants

Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial

Prisma Health-Upstate

NCT01926795

Phase Distribution

PhaseTrial count
Phase 3 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Tibial Fractures Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Tibial Fractures, and 8 of those are currently open to recruitment — roughly 62% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Tibial Fractures shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Tibial Fractures is led by Major Extremity Trauma Research Consortium with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Tibial Fractures?

PlainTrial tracks 13 US clinical trials for Tibial Fractures, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Tibial Fractures?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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