Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Tibial Fractures: later-stage trial registry
8 of 13 indexed Tibial Fractures trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 8 currently recruiting · #1,315 of 28,707 conditions by registered trial count
Tibial Fractures: 13 US clinical trials tracked, 8 recruiting.
Tibial Fractures is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Major Extremity Trauma Research Consortium, running 2 of these trials.
Enrollment posture brief
Registry condition tibial-fractures
OPEN 8 | RECR 62% | LATE 3 | EARLY 0 | RANK #1315 | SPON 2
Volume-matched condition peers
Nearest open-share peer: High Risk Myelodysplastic Syndrome (62% recruiting · 13 trials)
Tibial Fractures lists 8 open slots (62% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Tibial Fractures on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Tibial Fractures is recruiting above its size-band peers.
8 of 13 indexed trials (61.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Tibial Fractures research.
Major Extremity Trauma Research Consortium accounts for 2 of 13 trials (15.4%). 11 distinct sponsors appear on at least one study for this condition label.
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Typical Tibial Fractures enrolment sits around 100 participants.
Median target enrolment is 100 among the 13 trials that report a genuine target (sentinel values excluded). 6 of those (46.2%) plan for fewer than 100 participants.
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Tibial Fractures research is mostly interventional.
11 interventional and 2 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial
Major Extremity Trauma Research Consortium
NCT07006675
Intramedullary Calcium Sulfate Antibiotic Depot
Wake Forest University Health Sciences
NCT05766670
Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial
Wake Forest University Health Sciences
NCT05421741
Intramedullary Bone Grafting for Open Tibial Shaft Fractures
University of Louisville
NCT03891888
Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing
University of Alabama at Birmingham
NCT06679049
Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)
Major Extremity Trauma Research Consortium
NCT05889559
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
United States Naval Medical Center, San Diego
NCT05652881
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
Denver Health and Hospital Authority
NCT06496035
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
AO Innovation Translation Center
NCT04113044
A Post-Market Clinical Evaluation of the Treatment of Tibia Fractures With the T2 Alpha Tibia Nailing System
Stryker Trauma and Extremities
NCT04015167
Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture
Brian W. Noehren
NCT05274022
Suprapatellar Versus Infrapatellar Nailing in Tibial Fractures: A Pilot Study
Florida Orthopaedic Institute
NCT01341418
Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial
Prisma Health-Upstate
NCT01926795
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Tibial Fractures records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Tibial Fractures trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Tibial Fractures page
13 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Tibial Fractures trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Major Extremity Trauma Research Consortium sponsors the most Tibial Fractures trials on record, review their full trial history before evaluating a specific study. See Major Extremity Trauma Research Consortium's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tibial Fractures condition card totals 13 registered trials; most-linked intervention Standard Intramedullary Nail; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.