Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03891888 · ClinicalTrials.gov registry record · NA
Intramedullary Bone Grafting for Open Tibial Shaft Fractures
A NA study of Tibial Fractures and Nonunion of Fracture, sponsored by University of Louisville.
- Recruiting
- Registry status
- NA
- Development phase
- 130
- Enrollment target
- 2
- Study locations
NCT03891888: Recruiting NA study of Tibial Fractures and Nonunion of Fracture, sponsored by University of Louisville.
NCT03891888 is a NA study of Tibial Fractures and Nonunion of Fracture that is actively recruiting participants, run by University of Louisville. The registered enrollment target is 130 participants, below the 329-participant average among 12 other Tibial Fractures trials with a reported enrollment target (60% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03891888, a NA study of Tibial Fractures and Nonunion of Fracture, is actively recruiting participants, sponsored by University of Louisville.
- RECRUITING
- Registry status
- NA
- Development phase
- 130 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study will examine if there is a difference between the time to full union between the control group and the study group. Each group will be composed of patients who have an open fracture in the mid tibia. Both groups will undergo primary fixation via reamed intramedulary nailing (IMN), a common treatment for tibia shaft fractures in adults. The study group will have a bone graft applied to the open cortex of the fracture. The bone graft will be composed of the intramedullary reamings, which are a byproduct produced when the intramedullary canal is reamed in preparation for insertion of the IMN.
Conditions Studied
Interventions
- PROCEDURE Intramedullary Bone Graft
Study Locations (2)
Kentucky
- University of Louisville Hospital - Louisville
- University of Louisville Hospital - Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2020-03-26 |
| Est. Completion | 2025-02 |
| Phase | NA |
What NCT03891888 shows while recruiting
NCT03891888 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 329-participant average among 12 other Tibial Fractures trials with a reported enrollment target (60% lower).
The record links to 3 conditions, with Tibial Fractures appearing as the primary indexed condition, and to 1 intervention - of which Intramedullary Bone Graft is the first listed.
NCT03891888 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT03891888 about?
NCT03891888 is a clinical study titled "Intramedullary Bone Grafting for Open Tibial Shaft Fractures". This study will examine if there is a difference between the time to full union between the control group and the study group. Each group will be composed of patients who have an open fracture in the mid tibia. Both groups will undergo primary fixation via reamed intramedulary nailing (IMN), a commo...
What is the current status of trial NCT03891888?
This trial is currently recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2020-03-26. Estimated completion is 2025-02.
What conditions does trial NCT03891888 study?
This clinical trial studies the following conditions: Tibial Fractures, Nonunion of Fracture, Delayed Union of Fracture.
What interventions are being tested in trial NCT03891888?
The interventions under investigation include: Intramedullary Bone Graft (PROCEDURE).
Who is sponsoring clinical trial NCT03891888?
This trial is sponsored by University of Louisville, which has 217 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03891888 being conducted?
This trial has 2 study locations across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tibial Fractures
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03891888's enrollment target sits among peer trials
130 5th of 12 higher than 8 of 12 other Tibial Fractures trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tibial Fractures trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing
RECRUITING · NA
-
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
RECRUITING · NA
-
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
RECRUITING · NA
-
Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)
RECRUITING · NA
-
Suprapatellar Versus Infrapatellar Nailing in Tibial Fractures: A Pilot Study
COMPLETED · NA
-
Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01492036 · 130 participants
Long-Term Follow-Up of Recipient of Gene Transfer Research
- NCT01631617 · 130 participants · Phase 2
Effects of Treatments on Atopic Dermatitis
- NCT02368041 · 130 participants
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure
- NCT02604277 · 130 participants · NA
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI