Major Extremity Trauma Research Consortium

30 total trials 7 currently recruiting 21 completed

Major Extremity Trauma Research Consortium sponsors 30 registered US clinical trials on ClinicalTrials.gov, 7 of them currently recruiting, and 21 completed. 9 of these trials are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Operative Surgical Site Infection, with 3 trials.

Trial Pipeline

30 total, page 1 of 1

RECRUITING Phase 3

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

NCT06337292

RECRUITING NA

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

NCT05889559

RECRUITING Phase 2

Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

NCT04789044

RECRUITING Phase 3

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

NCT05699174

RECRUITING Phase 2

Multicenter Trial Evaluating the Safety and Efficacy of Autologous Volar Fibroblast Injection Into the Terminal Limb of Amputees.

NCT04839497

RECRUITING Phase 3

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

NCT07006675

RECRUITING Phase 3

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

NCT04678154

ACTIVE NOT RECRUITING NA

Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures

NCT04028414

ACTIVE NOT RECRUITING NA

Rehabilitation Enhanced by Partial Arterial Inflow Restrictions

NCT02746458

COMPLETED

Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion

NCT05143476

COMPLETED Phase 3

Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

NCT04597008

COMPLETED

Patient-Specific Precision Injury Signatures in Multiply Injured Orthopaedic Patients

NCT03772730

COMPLETED NA

Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries

NCT03562364

COMPLETED

The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma

NCT04047030

COMPLETED NA

Improving Recovery After Orthopaedic Trauma: Cognitive-Behavioral Based Physical Therapy (CBPT)

NCT03335657

COMPLETED Phase 3

PREVENTion of Clot in Orthopaedic Trauma

NCT02984384

COMPLETED

Study of Nerve Repair and Reconstruction Associated With Major Extremity Trauma

NCT02718768

COMPLETED

Prosthetic Fit Assessment in Transtibial Amputees Secondary to Trauma

NCT02540681

COMPLETED Phase 3

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO)

NCT02227446

COMPLETED NA

PRIORITI-MTF Study- Testing Patient Response to the IDEO

NCT02158884

COMPLETED

Streamlining Trauma Research Evaluation With Advanced Measurement

NCT02079714

COMPLETED NA

Randomized Trial to Assess PO Versus IV Antibiotics

NCT01714596

COMPLETED Phase 3

Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)

NCT01789216

COMPLETED NA

Improving Activity and Quality of Life Following Orthopaedic Trauma: The Trauma Collaborative Care Study (TCCS)

NCT01907893

COMPLETED NA

Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery

NCT01798810

COMPLETED NA

Transtibial Amputation Outcomes Study

NCT01821976

COMPLETED NA

Predicting Acute Compartment Syndrome (PACS)

NCT01561261

COMPLETED

Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol

NCT01606501

COMPLETED

Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage

NCT01496014

COMPLETED Phase 3

Assessment of Fixation Strategies for Severe Open Tibia Fractures

NCT01494519

What the Pipeline for Major Extremity Trauma Research Consortium Shows

According to the ClinicalTrials.gov registry, Major Extremity Trauma Research Consortium is linked to 30 US clinical trials across every stage of research activity. Of those, 7 studies are currently recruiting, about 23% of the sponsor's indexed portfolio, and 21 are already marked complete, representing roughly 70% of the total.

The phase mix for Major Extremity Trauma Research Consortium reports 9 late-stage studies (Phase 3 and Phase 4 combined) and 2 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Major Extremity Trauma Research Consortium is Post Operative Surgical Site Infection with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.