Major Extremity Trauma Research Consortium

Open enrollment with a later-stage pipeline tilt

According to ClinicalTrials.gov-derived indexes, Major Extremity Trauma Research Consortium sits in the top decile of US sponsors by registered trial count (#538 of 15,742 sponsors by registered trial count).

30 total trials 7 currently recruiting 21 completed later-stage tilt top decile by trial count

Major Extremity Trauma Research Consortium: 30 sponsored US clinical trials, 7 recruiting.

Major Extremity Trauma Research Consortium sponsors 30 registered US clinical trials on ClinicalTrials.gov, 7 of them currently recruiting, and 21 completed. 9 of these trials are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Operative Surgical Site Infection, with 3 trials.

Top-decile sponsor footprint

Major Extremity Trauma Research Consortium ranks in the top decile of sponsors by registered trial count (#538 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

21 of 21 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

30 total, page 1 of 1

RECRUITING Phase 3

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

NCT06337292

RECRUITING NA

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

NCT05889559

RECRUITING Phase 2

Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)

NCT04789044

RECRUITING Phase 3

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

NCT05699174

RECRUITING Phase 2

Multicenter Trial Evaluating the Safety and Efficacy of Autologous Volar Fibroblast Injection Into the Terminal Limb of Amputees.

NCT04839497

RECRUITING Phase 3

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

NCT07006675

RECRUITING Phase 3

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

NCT04678154

ACTIVE NOT RECRUITING NA

Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures

NCT04028414

ACTIVE NOT RECRUITING NA

Rehabilitation Enhanced by Partial Arterial Inflow Restrictions

NCT02746458

COMPLETED

Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion

NCT05143476

COMPLETED Phase 3

Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

NCT04597008

COMPLETED

Patient-Specific Precision Injury Signatures in Multiply Injured Orthopaedic Patients

NCT03772730

COMPLETED NA

Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries

NCT03562364

COMPLETED

The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma

NCT04047030

COMPLETED NA

Improving Recovery After Orthopaedic Trauma: Cognitive-Behavioral Based Physical Therapy (CBPT)

NCT03335657

COMPLETED Phase 3

PREVENTion of Clot in Orthopaedic Trauma

NCT02984384

COMPLETED

Study of Nerve Repair and Reconstruction Associated With Major Extremity Trauma

NCT02718768

COMPLETED

Prosthetic Fit Assessment in Transtibial Amputees Secondary to Trauma

NCT02540681

COMPLETED Phase 3

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO)

NCT02227446

COMPLETED NA

PRIORITI-MTF Study- Testing Patient Response to the IDEO

NCT02158884

COMPLETED

Streamlining Trauma Research Evaluation With Advanced Measurement

NCT02079714

COMPLETED NA

Randomized Trial to Assess PO Versus IV Antibiotics

NCT01714596

COMPLETED Phase 3

Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)

NCT01789216

COMPLETED NA

Improving Activity and Quality of Life Following Orthopaedic Trauma: The Trauma Collaborative Care Study (TCCS)

NCT01907893

COMPLETED NA

Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery

NCT01798810

COMPLETED NA

Transtibial Amputation Outcomes Study

NCT01821976

COMPLETED NA

Predicting Acute Compartment Syndrome (PACS)

NCT01561261

COMPLETED

Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol

NCT01606501

COMPLETED

Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage

NCT01496014

COMPLETED Phase 3

Assessment of Fixation Strategies for Severe Open Tibia Fractures

NCT01494519

Where Major Extremity Trauma Research Consortium enrollment is open (later-stage tilt)

7 recruiting of 30 indexed (23% open); 21 completed (70%).

Phase mix: 9 late (III/IV) vs 2 early (I/II) (later-stage heavy).

Top condition: Post Operative Surgical Site Infection (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Major Extremity Trauma Research Consortium: open-pipeline peers nationwide

Peers matched on 30 registered trials and 23% open enrollment, not the therapeutic-area sidebar.

Major Extremity Trauma Research Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080100 0%5%10%15%20%25% Total trials Recruiting share Major Extremity Trauma Research ConsortiumBiotronikCharles Drew University of Medicine and ScienceChiesi Farmaceutici S.p.A.Debiopharm InternationalScripps HealthHugo W. Moser Research Institute at Kennedy KriegerTexas A&M UniversityChugai Pharmaceutical
Major Extremity Trauma Research Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Major Extremity Trauma Research Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 30 trials (± recruiting share)

Sponsors near 23% open enrollment (± trial volume)

What to do with this Major Extremity Trauma Research Consortium page

30 registered trials is a research-attention snapshot, not an endorsement of Major Extremity Trauma Research Consortium or any single study.

  • 7 of Major Extremity Trauma Research Consortium's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Operative Surgical Site Infection is the condition Major Extremity Trauma Research Consortium studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Operative Surgical Site Infection trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Major Extremity Trauma Research Consortium pipeline card: 30 registered trials from official public datasets.Report a data error.