Prisma Health-Upstate

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Prisma Health-Upstate sits in the top decile of US sponsors by registered trial count (#312 of 15,742 sponsors by registered trial count).

67 total trials 6 currently recruiting 50 completed top decile by trial count

Prisma Health-Upstate: 67 sponsored US clinical trials, 6 recruiting.

Prisma Health-Upstate sponsors 67 registered US clinical trials on ClinicalTrials.gov, 6 of them currently recruiting, and 50 completed. 10 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cancer, with 3 trials.

Top-decile sponsor footprint

Prisma Health-Upstate ranks in the top decile of sponsors by registered trial count (#312 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

50 of 58 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

67 total, page 1 of 2

RECRUITING NA

Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine

NCT07202039
RECRUITING NA

Building Retention and Initiation Through Delivery of Peer-Guided Evidence-Based Practices

NCT07541417
RECRUITING

Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder

NCT07594717
RECRUITING Phase 4

Preoperative Acetazolamide

NCT07101250
RECRUITING Phase 4

Intracervical Vasopressin

NCT07102615
RECRUITING

Prevent Cancer- Greenville

NCT04947098
ACTIVE NOT RECRUITING

The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI

NCT06907693
ACTIVE NOT RECRUITING Phase 4

Methocarbamol in Ventral and Inguinal HR

NCT05388929
ACTIVE NOT RECRUITING Phase 2

Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis

NCT04039750
COMPLETED NA

Peer to Peer (P2P): Mental Health Interventions With Persons With Substance Use Disorders

NCT06803810
COMPLETED NA

STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists

NCT06384781
COMPLETED NA

Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers

NCT06186960
COMPLETED Phase 4

Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA

NCT06291727
COMPLETED NA

Self-Administered 2-Hour Oral Glucose Tolerance Test

NCT06099509
COMPLETED NA

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder

NCT06102200
COMPLETED NA

E-cigarettes as a Harm Reduction Strategy

NCT06277271
COMPLETED NA

Randomized Controlled Trial of Virtual Reality Assisted Guided Imagery (VRAGI) for Pain in Advanced Cancer Patients.

NCT05348174
COMPLETED NA

Pannus Assistance Needed for Obstetric Ultrasound Studies

NCT05764408
COMPLETED NA

Pannus Retraction for Ultrasound Evaluation of the Obese Gravida: A Pilot Study

NCT05527327
COMPLETED Phase 4

Wearing-Off Period of Pharmacological Dilation and Anisocoria

NCT05238233
TERMINATED Phase 2

Phase II Study of Tazemetostat in Solid Tumors Harboring an ARID1A Mutation

NCT05023655
COMPLETED

Airway Management Skills Amongst Anesthesia Providers

NCT05055401
COMPLETED

Lateralization After IntraMedullary Nailing of InterTrochanteric Hip Fractures, Clinical and Radiographic Outcomes

NCT05094791
COMPLETED NA

The Use of Virtual Reality During Breast Ultrasound-Guided Biopsy Procedures

NCT05042999
COMPLETED NA

Eliminating HCV in Rural South Carolina Utilizing NP Led Mobile Clinics and Virtual Care Coordination

NCT05369507
COMPLETED NA

Pregnancy-Related Hypertension: Adherence to a New Type of Monitoring

NCT04823949
COMPLETED Phase 4

Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension

NCT04790279
COMPLETED NA

VR Ultrasound Guided Breast Localization

NCT04251507
COMPLETED NA

Improving Pain Perceptions After Initiating a Delivery Application

NCT04822493
COMPLETED NA

CBT4CBT-Buprenorphine + Recovery Coach for Office-based Buprenorphine

NCT04824404
COMPLETED NA

HCV-Smoking Cessation Study

NCT05466981
TERMINATED Phase 1

Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19

NCT04545008
COMPLETED

COVID-19 on Placental Gene Expression and Pathology

NCT04585945
COMPLETED Phase 2

Therapeutic Plasma Exchange Alone or in Combination With Ruxolitinib in COVID-19 Associated CRS

NCT04374149
COMPLETED Phase 3

Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use

NCT05386069
COMPLETED NA

Barriers to Substance Use Disorder Recovery

NCT04098614
COMPLETED

Outpatient Cervical Ripening

NCT04041687
COMPLETED Phase 3

Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)

NCT03945357
COMPLETED

Spinal Cord Stimulation in Chemotherapy Induced Neuropathy

NCT03764514
COMPLETED

Body Composition During Cancer Treatment

NCT03784911
COMPLETED

Body Composition Post Cancer Treatment

NCT03690401
COMPLETED

Opioid Sparing Pain Management Strategy

NCT04269109
COMPLETED NA

Inpatient Link to Addiction Recovery

NCT04098601
COMPLETED NA

HRV-B for Symptom Management in Sickle Cell Patients

NCT03383913
COMPLETED

Treatment of Pediatric Mid-shaft Clavicle Fractures: A Prospective, Observational Study

NCT03402269
COMPLETED NA

FAVOR Opioid Recovery Coaching Evaluation

NCT03798470
TERMINATED Phase 4

Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery

NCT03383198
COMPLETED

Evaluating Palpation Guided Injections in Trapeziometacarpal Arthritis

NCT03147118
TERMINATED Phase 4

Amniotic Membrane Allograft Application in the Management of Venous Leg Ulcerations

NCT02929056
TERMINATED Phase 2

Durvalumab in Combination With Tremelimumab in Subjects With Advanced Rare Solid Tumors

NCT02938793
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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 2
Phase 4 8

Therapeutic Areas

Cancer 3
Hepatitis C 2
Substance Use Disorders 2
Wound Vac 1
High Energy Midshaft Clavicle Fractures 1
Suture 1
Obesity Complicating Childbirth 1
Fetal Anomaly 1
Laparoscopic Cholecystectomy 1
High-Risk Cancer 1

What is open in the Prisma Health-Upstate pipeline

6 recruiting of 67 indexed (9% open); 50 completed (75%).

Phase mix: 10 late (III/IV) vs 7 early (I/II) (balanced across stages).

Top condition: Cancer (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Prisma Health-Upstate: open-pipeline peers nationwide

Peers matched on 67 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Prisma Health-Upstate sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080 0%5%10%15%20%25% Total trials Recruiting share Prisma Health-UpstateUniversity at BuffaloVanda PharmaceuticalsAlkermesCornell UniversityGrifols TherapeuticsDBV TechnologiesFlorida Gulf Coast UniversityGenfit
Prisma Health-Upstate sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Prisma Health-Upstate sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 67 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Prisma Health-Upstate page

67 registered trials is a research-attention snapshot, not an endorsement of Prisma Health-Upstate or any single study.

  • 6 of Prisma Health-Upstate's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Cancer is the condition Prisma Health-Upstate studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Prisma Health-Upstate pipeline card: 67 registered trials from official public datasets.Report a data error.