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NCT05515237 · ClinicalTrials.gov registry record · NA

Constraint-Induced Movement Therapy Plus Sensory Components After Stroke

A NA study of Stroke and Upper Extremity Paresis, sponsored by University of Alabama at Birmingham.

Recruiting
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT05515237: Recruiting NA study of Stroke and Upper Extremity Paresis, sponsored by University of Alabama at Birmingham.

NCT05515237 is a NA study of Stroke and Upper Extremity Paresis that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 15 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05515237, a NA study of Stroke and Upper Extremity Paresis, is actively recruiting participants, sponsored by University of Alabama at Birmingham.

RECRUITING
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following strategies utilized: behavioral strategies are implemented to improve the use of the more- affected limb in life situation called a Transfer Package (TP), motor training using a technique called shaping to make progress in successive approximations, repetitive, task oriented training, and strategies to encourage or constrain participants to use the more-affected extremity including restraint of the less-affected arm in the upper extremity (UE) protocol. Numerous studies examining the application of CI therapy with UE rehabilitation after stroke have demonstrated strong evidence for improving the amount of use and the quality of the more-affected UE functional use in the participant's daily life situation. CI Therapy studies with adults, to date, have explored intensive treatment for participants with a range from mild-to-severe motor impairment following stroke with noted motor deficits and limited use of the more-affected arm and hand in everyday activities. Each CI Therapy protocol was designed for the level of impairment demonstrated by participants recruited for the study. However, often following stroke, patients not only have motor deficits but somatosensory impairments as well. The somatosensory issues have not, as yet, been systematically measured and trained in CI Therapy protocols with adults and represent an understudied area of stroke recovery. We hypothesize that participants with mild-to-severe motor impairment and UE functional use deficits can benefit from CI therapy protocols that include somatosensory measurement and training components substituted for portions of motor training without loss in outcome measure gains. Further, we hypothesize that adults can improve somatosensory outcomes as a result of a combined CI therapy plus

Primary Outcome

The Motor Activity Log is a semi-structured interview that assesses the amount of use and the quality of use of the more-affected UE in 30 activities of daily living. This test is used to determine the change how much and how well the participant uses the more-affected arm and hand outside of the laboratory setting and in the life situation. It is administered before and after treatment. The score is derived from two scales that are each 0-5 and reported as a mean for the Amount of Use (AOU) and

Interventions

  • BEHAVIORAL Grade 2-5 CI Therapy + Sensory Components

Study Locations (1)

Alabama

  • University of Alabama at Birmingham - Birmingham

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2023-03-30
Est. Completion 2026-06
Phase NA
University of Alabama at Birmingham

1,160 total trials

What NCT05515237 shows while recruiting

NCT05515237 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).

The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Grade 2-5 CI Therapy + Sensory Components is the first listed.

NCT05515237 reports a single indexed study location in Alabama.

Frequently Asked Questions

What is clinical trial NCT05515237 about?

NCT05515237 is a clinical study titled "Constraint-Induced Movement Therapy Plus Sensory Components After Stroke". Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following strategies utilized: behavioral strategies are implemented to improve the us...

What is the current status of trial NCT05515237?

This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2023-03-30. Estimated completion is 2026-06.

What conditions does trial NCT05515237 study?

This clinical trial studies the following conditions: Stroke, Upper Extremity Paresis, CVA (Cerebrovascular Accident).

What interventions are being tested in trial NCT05515237?

The interventions under investigation include: Grade 2-5 CI Therapy + Sensory Components (BEHAVIORAL).

Who is sponsoring clinical trial NCT05515237?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05515237 being conducted?

This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05515237's enrollment target sits among peer trials

15 391st of 454 higher than 56 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05515237, the US trial registry maintained by the National Library of Medicine. NCT05515237 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.