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NCT06533176 · ClinicalTrials.gov registry record · NA
Real-time Personalized Brain State-dependent TMS After Stroke
A NA study of Stroke, sponsored by Sara Hussain.
- Recruiting
- Registry status
- NA
- Development phase
- 37
- Enrollment target
- 1
- Study location
NCT06533176: Recruiting NA study of Stroke, sponsored by Sara Hussain.
NCT06533176 is a NA study of Stroke that is actively recruiting participants, run by Sara Hussain. The registered enrollment target is 37 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06533176, a NA study of Stroke, is actively recruiting participants, sponsored by Sara Hussain.
- RECRUITING
- Registry status
- NA
- Development phase
- 37 participants
- Enrollment target
- 1
- Study location
Study Summary
Transcranial magnetic stimulation (TMS) interventions could feasibly strengthen residual corticospinal tract (CST) connections and enhance recovery of paretic upper extremity function after stroke. This project will test whether personalized brain state-dependent TMS can activate the residual corticospinal tract better than standard TMS, and evaluate the relationship between this activation and upper extremity motor impairment.
Primary Outcome
Peak-to-peak MEP amplitudes elicited by single TMS pulses delivered during personalized brain activity patterns corresponding to strong corticospinal transmission and random brain activity patterns will be measured. At the individual participant level, all MEP amplitudes will be normalized to the mean MEP amplitude observed in that participant. Mean normalized MEP amplitudes will be used to calculate the percentage MEP amplitude difference between the two brain activity patterns (i.e., strong an
Conditions Studied
Interventions
- DEVICE Personalized brain state-dependent single-pulse TMS
Study Locations (1)
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2024-08-01 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT06533176 shows while recruiting
NCT06533176 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Personalized brain state-dependent single-pulse TMS is the first listed.
NCT06533176 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT06533176 about?
NCT06533176 is a clinical study titled "Real-time Personalized Brain State-dependent TMS After Stroke". Transcranial magnetic stimulation (TMS) interventions could feasibly strengthen residual corticospinal tract (CST) connections and enhance recovery of paretic upper extremity function after stroke. This project will test whether personalized brain state-dependent TMS can activate the residual cortic...
What is the current status of trial NCT06533176?
This trial is currently recruiting. It is a NA study. The enrollment target is 37 participants. The study started on 2024-08-01. Estimated completion is 2026-08.
What conditions does trial NCT06533176 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT06533176?
The interventions under investigation include: Personalized brain state-dependent single-pulse TMS (DEVICE).
Who is sponsoring clinical trial NCT06533176?
This trial is sponsored by Sara Hussain, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06533176 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06533176's enrollment target sits among peer trials
37 279th of 454 higher than 174 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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