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ClinicalTrials.gov 64 recruiting now early-phase tilt #73 of 28,707 conditions

Stress: early-phase trial registry

64 of 153 indexed Stress trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #73 of 28,707 conditions by registered trial count.

153 US clinical trials · 64 currently recruiting · #73 of 28,707 conditions by registered trial count

Stress: 153 US clinical trials tracked, 64 recruiting.

Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.

Enrollment posture brief

Registry condition stress

OPEN 64 | RECR 42% | LATE 2 | EARLY 12 | RANK #73 | SPON 5

Nearest open-share peer: Colorectal Neoplasms (42% recruiting · 55 trials)

PTSD49.7%Sleep48%Stress (this)42%Insomnia40.8%Atopic Dermatitis36.4%
Open-enrollment share among volume-matched conditions near Stress

Stress lists 64 open slots (42% of 153 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stress on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stress is recruiting above its size-band peers.

    64 of 153 indexed trials (41.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stress trials is spread across many organizations.

    Virginia Commonwealth University accounts for 5 of 153 trials (3.3%). 113 distinct sponsors appear on at least one study for this condition label.

  3. Typical Stress enrolment sits around 80 participants.

    Median target enrolment is 80 among the 153 trials that report a genuine target (sentinel values excluded). 86 of those (56.2%) plan for fewer than 100 participants.

  4. Stress research is mostly interventional.

    142 interventional and 11 observational studies make up this index (92.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 26Phase 42

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 4 2

Named interventions

Most-linked intervention names on Stress records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Stress Other
2 trials
Stress Reduction Behavioral
2 trials
Trier Social Stress Test Behavioral
2 trials
Cognitive Behavioral Therapy (CBT) Behavioral
2 trials
Placebo Dietary supplement
2 trials
Social Media Usage Manipulation Behavioral
1 trials
Arousal Reappraisal Behavioral
1 trials

US sites by state

Facility locations filed on Stress trials. A trial with sites in several states counts in each.

California 20 trials
Florida 18 trials
Massachusetts 17 trials
Texas 8 trials
New York 8 trials
Connecticut 7 trials
Virginia 6 trials
Alabama 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stress page

153 registered trials, 64 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress condition card totals 153 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.