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Sleep Apnea: full-pipeline trial registry
16 of 37 indexed Sleep Apnea trials are currently recruiting.
Corpus placement: #406 of 28,707 conditions by registered trial count.
37 US clinical trials · 16 currently recruiting · #406 of 28,707 conditions by registered trial count
Sleep Apnea: 37 US clinical trials tracked, 16 recruiting.
Sleep Apnea is the subject of 37 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 3 of these trials.
Enrollment posture brief
Registry condition sleep-apnea
OPEN 16 | RECR 43% | LATE 4 | EARLY 6 | RANK #406 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Recurrent Diffuse Large B-Cell Lymphoma (43% recruiting · 44 trials)
Sleep Apnea lists 16 open slots (43% of 37 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Sleep Apnea on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Sleep Apnea is recruiting above its size-band peers.
16 of 37 indexed trials (43.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Sleep Apnea trials is spread across many organizations.
VA Office of Research and Development accounts for 3 of 37 trials (8.1%). 30 distinct sponsors appear on at least one study for this condition label.
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Typical Sleep Apnea enrolment sits around 100 participants.
Median target enrolment is 100 among the 37 trials that report a genuine target (sentinel values excluded). 18 of those (48.6%) plan for fewer than 100 participants.
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Sleep Apnea research is mostly interventional.
28 interventional and 9 observational studies make up this index (75.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
37 total, page 1 of 1
Research Framework Exploring Sleep Health
Scripps Translational Science Institute
NCT05197738
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
University of Miami
NCT06089161
Mechanisms of Prediabetic States in Sleep Apnea
University of Chicago
NCT04234217
Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?
University of California, San Diego
NCT05094271
Do Endotypes Predict Response and Sequelae in OSA Patients
University of California, San Diego
NCT04875364
Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study
Yale University
NCT05612594
Sleep Disordered Breathing With Opioid Use
VA Office of Research and Development
NCT05589753
Sleep Apnea in Elderly
VA Office of Research and Development
NCT02703220
Reaching for Equity in Sleep Apnea Treatment (REST) Study
University of California, San Francisco
NCT04209985
Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
John D. Dingell VA Medical Center
NCT02922894
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk
University of Utah
NCT06649929
Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea
Shionogi Apnimed Sleep Science
NCT06776432
Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
University of South Florida
NCT02630121
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
Vivek Jain
NCT03860233
Janus II Feasibility
Zoll Medical Corporation
NCT06556693
Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury
VA Office of Research and Development
NCT05536076
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
Technology-Supported Treatment of Sleep Apnea in Prediabetes
University of Chicago
NCT04225507
Sleep Aging and Risk for Alzheimer's 2.0
NYU Langone Health
NCT03278119
Obstructive Sleep Apnea and Metabolic Health
Ohio State University
NCT02978937
Influence of Sleep Apnea on Risk of Atrial Fibrillation
The Cleveland Clinic
NCT02576587
The Prevalence and Risk Factors of Sleep Disordered Breathing in a Heart Failure Program
Ohio State University
NCT00679822
Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy
Johns Hopkins University
NCT02454153
Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography
Philips Respironics
NCT00836758
Football Players Health Study In Person Assessments Study
Massachusetts General Hospital
NCT03866564
A Multi-Center Study to Assess the Performance of Saturation Patterns.
Medtronic - MITG
NCT00775346
Prodigy, a Level 2 Sleep Study Device, Validation Study
Cerebra Medical
NCT05115305
Effect of Treating Sleep Apnea on Cognition in Patients With Dementia
University of California, San Diego
NCT00477828
A Pilot Study of CPAP Adherence Promotion by Peer Buddies With Sleep Apnea
US Department of Veterans Affairs
NCT01164683
Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B
Brigham and Women's Hospital
NCT01738009
Atrial Fibrillation Recurrence in Sleep Apnea
Mayo Clinic
NCT00263757
CPAP Efficacy in Post-COVID-19 Patients With Sleep Apnea
Venkatesh Krishnamurthy
NCT06052514
Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Medical College of Wisconsin
NCT01196117
Evaluation of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
Invicta Medical
NCT06283030
Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea
University of Pennsylvania
NCT00194376
Long QT Syndrome and Sleep Apnea
The Cleveland Clinic
NCT03678311
Comparison of Standing Versus Supine 3D Cone Beam Computed Tomography in Patient With Obstructive Sleep Apnea
Manhattan Beach Orthodontics
NCT04874727
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Sleep Apnea records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Sleep Apnea trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Sleep Apnea page
37 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 16 Sleep Apnea trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Sleep Apnea trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sleep Apnea condition card totals 37 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.