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Sleep Apnea
Open-data reference.
36 US clinical trials · 16 currently recruiting
Active & Recent Trials
Research Framework Exploring Sleep Health
Scripps Translational Science Institute
NCT05197738
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
University of Miami
NCT06089161
Mechanisms of Prediabetic States in Sleep Apnea
University of Chicago
NCT04234217
Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?
University of California, San Diego
NCT05094271
Do Endotypes Predict Response and Sequelae in OSA Patients
University of California, San Diego
NCT04875364
Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study
Yale University
NCT05612594
Sleep Disordered Breathing With Opioid Use
VA Office of Research and Development
NCT05589753
Sleep Apnea in Elderly
VA Office of Research and Development
NCT02703220
Reaching for Equity in Sleep Apnea Treatment (REST) Study
University of California, San Francis
NCT04209985
Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
John D. Dingell VA Medical Center
NCT02922894
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk
University of Utah
NCT06649929
Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea
Shionogi Apnimed Sleep Science
NCT06776432
Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
University of South Florida
NCT02630121
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
Vivek Jain
NCT03860233
Janus II Feasibility
Zoll Medical Corporation
NCT06556693
Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury
VA Office of Research and Development
NCT05536076
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
Technology-Supported Treatment of Sleep Apnea in Prediabetes
University of Chicago
NCT04225507
Sleep Aging and Risk for Alzheimer's 2.0
NYU Langone Health
NCT03278119
Influence of Sleep Apnea on Risk of Atrial Fibrillation
The Cleveland Clinic
NCT02576587
The Prevalence and Risk Factors of Sleep Disordered Breathing in a Heart Failure Program
Ohio State University
NCT00679822
Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy
Johns Hopkins University
NCT02454153
Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography
Philips Respironics
NCT00836758
Football Players Health Study In Person Assessments Study
Massachusetts General Hospital
NCT03866564
A Multi-Center Study to Assess the Performance of Saturation Patterns.
Medtronic - MITG
NCT00775346
Prodigy, a Level 2 Sleep Study Device, Validation Study
Cerebra Medical
NCT05115305
Effect of Treating Sleep Apnea on Cognition in Patients With Dementia
University of California, San Diego
NCT00477828
A Pilot Study of CPAP Adherence Promotion by Peer Buddies With Sleep Apnea
US Department of Veterans Affairs
NCT01164683
Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B
Brigham and Women's Hospital
NCT01738009
Atrial Fibrillation Recurrence in Sleep Apnea
Mayo Clinic
NCT00263757
CPAP Efficacy in Post-COVID-19 Patients With Sleep Apnea
Venkatesh Krishnamurthy
NCT06052514
Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Medical College of Wisconsin
NCT01196117
Evaluation of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
Invicta Medical
NCT06283030
Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea
University of Pennsylvania
NCT00194376
Long QT Syndrome and Sleep Apnea
The Cleveland Clinic
NCT03678311
Comparison of Standing Versus Supine 3D Cone Beam Computed Tomography in Patient With Obstructive Sleep Apnea
Manhattan Beach Orthodontics
NCT04874727
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sleep Apnea Trial Landscape
ClinicalTrials.gov lists 36 US studies indexed under Sleep Apnea, and 16 of those are currently open to recruitment — roughly 44% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Sleep Apnea shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Sleep Apnea is led by VA Office of Research and Development with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 36 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sleep Apnea?
PlainTrial tracks 36 US clinical trials for Sleep Apnea, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sleep Apnea?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.