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ClinicalTrials.gov 14 recruiting now official registry

Skin Cancer clinical trials

Every US clinical trial registered for Skin Cancer — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

42 US clinical trials · 14 currently recruiting

The research picture

Skin Cancer has 42 registered US clinical trials, 14 of them open to new participants right now — about 33% of the total.

14
recruiting participants now
33%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
5
top sponsor: H. Lee Moffitt Cancer Center and Research Institute

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 2,900 participants

Hybrid Effectiveness-Implementation Trial to Integrate Precision Skin Cancer Risk Feedback in FQHCs

H. Lee Moffitt Cancer Center and Research Institute

NCT07222995

RECRUITING NA 843 participants

Rural Adult and Youth Sun Protection Study

University of Utah

NCT06439979

RECRUITING Phase 3 528 participants

Undergraduate Skin Cancer Prevention Trial

University of Utah

NCT05634252

RECRUITING NA 400 participants

Adaptive Symptom Self-Management Immunotherapy Study

University of Arizona

NCT05715255

RECRUITING Phase 4 300 participants

Meloxicam in Mohs Micrographic Surgery

University of Oklahoma

NCT07200544

RECRUITING Phase 1 100 participants

Treating Basal and Squamous Cell Carcinomas With Fractional Laser and Tirbanibulin Ointment

Bruce Robinson, MD

NCT07010692

RECRUITING NA 48 participants

DNA Repair Activity in the Skin of Day and Night Shift Workers

Wright State University

NCT04122456

RECRUITING NA 40 participants

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

Dana-Farber Cancer Institute

NCT06298734

RECRUITING Phase 2 37 participants

Cryoablation+Ipilimumab+Nivolumab in Melanoma

Massachusetts General Hospital

NCT05779423

RECRUITING Early Phase 1 30 participants

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Rhode Island Hospital

NCT05702398

RECRUITING Early Phase 1 25 participants

A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision

Dana-Farber Cancer Institute

NCT06664151

RECRUITING 20 participants

Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers

University of Wisconsin, Madison

NCT06608511

RECRUITING 20 participants

Raman Spectroscopy and Skin Cancer

Renee Farrell

NCT06384924

RECRUITING Phase 2 14 participants

TIL Therapy in cSCC and MCC

Karam Khaddour, MD, MS

NCT07288073

ACTIVE NOT RECRUITING 4,082 participants

A Model for Genetic Susceptibility: Melanoma

Memorial Sloan Kettering Cancer Center

NCT00591500

ACTIVE NOT RECRUITING 1,889 participants

In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin

Memorial Sloan Kettering Cancer Center

NCT00588315

ACTIVE NOT RECRUITING 354 participants

Patient Satisfaction in Cutaneous Surgery

Northwestern University

NCT01535963

ACTIVE NOT RECRUITING Phase 2 50 participants

Randomized Study of Nivolumab+Ipilimumab+/- SBRT for Metastatic Merkel Cell Carcinoma

H. Lee Moffitt Cancer Center and Research Institute

NCT03071406

ACTIVE NOT RECRUITING NA 45 participants

A Community-based Educational Initiative to Raise Awareness of Melanoma and Other Skin Cancers.

NYU Langone Health

NCT07177638

ACTIVE NOT RECRUITING Phase 1 39 participants

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

DEKA Biosciences

NCT05704985

ACTIVE NOT RECRUITING Phase 2 34 participants

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

Memorial Sloan Kettering Cancer Center

NCT05574101

ACTIVE NOT RECRUITING Phase 1 26 participants

XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma

H. Lee Moffitt Cancer Center and Research Institute

NCT02721459

ACTIVE NOT RECRUITING Early Phase 1 14 participants

Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma

H. Lee Moffitt Cancer Center and Research Institute

NCT03543969

COMPLETED Phase 3 2,223 participants

Sun-safe Habits Intervention and Education

University of Utah

NCT04341064

COMPLETED NA 1,364 participants

Online Tailored Interventions & Relational Agents for Exercise and Sun Protection

University of Rhode Island

NCT01458002

COMPLETED 1,028 participants

DermaSensor Study of Primary Care Physician Use of Elastic-Scattering Spectroscopy (ESS) on Skin Lesions Suggestive of Skin Cancer

DermaSensor

NCT06690086

COMPLETED Phase 2 867 participants

Skin Cancer Prevention in a Pediatric Population

University of Colorado, Denver

NCT01464957

COMPLETED NA 323 participants

Melanoma Risk Assessment & Tailored Intervention

University of Pennsylvania

NCT01356771

COMPLETED NA 170 participants

Evaluation of Store-and-Forward Teledermatology Versus a Face-to-Face Assessment During a Skin Cancer Screening Event

University of California, Davis

NCT01820234

COMPLETED Phase 2 133 participants

Phase II Trial of Allovectin-7® for Metastatic Melanoma

Vical

NCT00044356

COMPLETED NA 94 participants

Comparison Of Video-based Versus Written Patient Education on Sunscreen

University of California, Davis

NCT00826306

COMPLETED NA 89 participants

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

Case Comprehensive Cancer Center

NCT06167096

COMPLETED 81 participants

Multi-Center Study to Evaluate the Performance of DermDx for Primary Care Physicians in the Detection of Skin Cancers

MetaOptima Technology

NCT06463860

COMPLETED NA 78 participants

EUREKA: Evaluating Ultraviolet Radiation Exposure in Kids for Adaptive Intervention

University of Utah

NCT07204704

COMPLETED NA 75 participants

Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery

Mayo Clinic

NCT00578214

COMPLETED 60 participants

Development and Validation of a New Digital Dermatoscope in the United States

Barco

NCT04047316

COMPLETED 42 participants

Health Communication in Families

Memorial Sloan Kettering Cancer Center

NCT00597961

COMPLETED Phase 1 30 participants

Assessing a Natural Product Plus Bioadhesive Nanoparticle (BNP) Sunscreen

Yale University

NCT05736224

COMPLETED NA 29 participants

Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer

Emory University

NCT01526486

COMPLETED Phase 2 24 participants

Phase II Study of Radiation Therapy and Vismodegib for Advanced Head/Neck Basal Cell Carcinoma

Sue Yom

NCT01835626

COMPLETED Phase 1 17 participants

Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma

H. Lee Moffitt Cancer Center and Research Institute

NCT02032810

COMPLETED Phase 2

Study of Talabostat and Cisplatin in Advanced Melanoma

Point Therapeutics

NCT00083252

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 8
Phase 3 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Skin Cancer Trial Landscape

ClinicalTrials.gov lists 42 US studies indexed under Skin Cancer, and 14 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Skin Cancer shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 16 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Skin Cancer is led by H. Lee Moffitt Cancer Center and Research Institute with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 42 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Skin Cancer?

PlainTrial tracks 42 US clinical trials for Skin Cancer, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Skin Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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