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NCT00588315 · ClinicalTrials.gov registry record
In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin
A clinical trial of Skin Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- 1,889
- Enrollment target
- 4
- Study locations
NCT00588315: Active study of Skin Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT00588315 is a study of Skin Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 1,889 participants, above the 417-participant average among 40 other Skin Cancer trials with a reported enrollment target (353% higher). The trial reports 4 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00588315, a study of Skin Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- 1,889 participants
- Enrollment target
- 4
- Study locations
Study Summary
The purpose of this study is to investigate new non-invasive imaging techniques for the evaluation of skin lesions, as well as normal skin. Our primary goal is to collect and study these images of different skin lesions along with matching biopsy specimens. The long-term goal is to develop a technique that will improve the early detection of skin cancer and eliminate the need for many skin biopsies. The High-resolution OCT (Apollo Medical Optics) device can provide both cross-sectional and en-face images with cellular information. Real-time color images through the same objective with OCT are also provided to show the OCT imaging location of lesion. The color image can be registered simultaneously on a larger dermoscopic image obtained by an external dermoscope. The imaging mode of cross-sectional, en-face and color image can be switched arbitrarily to align the lesion and obtain high-resolution images efficiently. The total imaging time is around 10 to 15 minutes depending on the number of images to be obtained. To help identify more diagnostic features of optical imaging and better understand their histology correlation, we have developed a novel technique called "precision biopsy". Precision biopsy is an optical imaging guided, feature-targeted mini-biopsy. Once the feature of interest is identified and isolated by the optical imaging, a 2.0 mm punch biopsy is performed. Besides cosmetic benefit of minimal scarring, this tissue sparing biopsy captures the "feature of interest" for histology revelation. Additionally, the histologic features of precision biopsy will be compared to images gathered by multi-modal optical imaging. The precision biopsy will also be compared to the traditional shave biopsy or shave excision, to determine whether the diagnostic information is comparable between the two methods. For live remote control (LRC) imaging consultation, MSK dermatologist will based on his clinical examination. An imaging technician will perform the clinical
Conditions Studied
Study Locations (4)
New York
- Memorial Sloan Kettering Westchester (Consent only) - Harrison
- Memorial Sloan Kettering Hauppauge (Consent only) - Hauppauge
- Memorial Sloan Kettering Cancer Center - New York
New Jersey
- Memorial Sloan Kettering Basking Ridge (Consent only) - Basking Ridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,889 participants |
| Start Date | 1999-11 |
| Est. Completion | 2026-12 |
What the registry record for NCT00588315 still lists
NCT00588315 is an observational study that tracks outcomes without assigning an intervention. Its 1,889 participants enrollment target places it among the larger protocols in the corpus, above the 417-participant average among 40 other Skin Cancer trials with a reported enrollment target (353% higher).
The record links to 1 condition, with Skin Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT00588315 reports a single indexed study location in New York, New Jersey.
Frequently Asked Questions
What is clinical trial NCT00588315 about?
NCT00588315 is a clinical study titled "In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin". The purpose of this study is to investigate new non-invasive imaging techniques for the evaluation of skin lesions, as well as normal skin. Our primary goal is to collect and study these images of different skin lesions along with matching biopsy specimens. The long-term goal is to develop a techniq...
What is the current status of trial NCT00588315?
This trial is currently active not recruiting. The enrollment target is 1,889 participants. The study started on 1999-11. Estimated completion is 2026-12.
What conditions does trial NCT00588315 study?
This clinical trial studies the following conditions: Skin Cancer.
Who is sponsoring clinical trial NCT00588315?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00588315 being conducted?
This trial has 4 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00588315's enrollment target sits among peer trials
1,889 4th of 40 higher than 37 of 40 other Skin Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Skin Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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