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NCT05574101 · ClinicalTrials.gov registry record · Phase 2

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

A Phase 2 study of Squamous Cell Carcinoma and Skin Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 2
Development phase
34
Enrollment target
13
Study locations

NCT05574101 is a Phase 2 study of Squamous Cell Carcinoma and Skin Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 34 participants, below the 103-participant average among 47 other Squamous Cell Carcinoma trials with a reported enrollment target (67% lower). The trial reports 13 study locations across 8 states.

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The verdict

NCT05574101, a Phase 2 study of Squamous Cell Carcinoma and Skin Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
34 participants
Enrollment target
13
Study locations

Study Summary

The purpose of the study is to see if the combination of radiation therapy and cemiplimab immunotherapy is an effective treatment for people with locally advanced, unresectable CSCC.

Interventions

  • DRUG Cemiplimab
  • RADIATION Radiotherapy

Study Locations (13)

New York

  • Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities) - Commack
  • Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
  • Memorial Sloan Kettering Nassau (All protocol activities) - Rockville Centre

New Jersey

  • Memorial Sloan Kettering Cancer Center at Basking Ridge (All Protocol Activities) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (All Protocol Activities) - Middletown
  • Memorial Sloan Kettering Bergen (All protocol activities) - Montvale

Colorado

  • University of Colorado (Data Collection Only) - Aurora

Florida

  • Moffitt Cancer Center (Data Collection Only) - Tampa

Ohio

  • Cleveland Clinic (Data Collection Only) - Cleveland

Pennsylvania

  • Fox Chase Cancer Center (Data Collection Only) - Philadelphia

South Carolina

  • Medical University of South Carolina - Charleston

Washington

  • University of Washington (Data Collection Only) - Seattle

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2022-10-06
Est. Completion 2026-10-06
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT05574101

The ClinicalTrials.gov registry entry for NCT05574101 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 103-participant average among 47 other Squamous Cell Carcinoma trials with a reported enrollment target (67% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Squamous Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Cemiplimab is the first listed.

NCT05574101 reports 13 study locations spanning 8 distinct geographic areas - top geographies include New York, New Jersey, Colorado.

Frequently Asked Questions

What is clinical trial NCT05574101 about?

NCT05574101 is a clinical study titled "A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer". The purpose of the study is to see if the combination of radiation therapy and cemiplimab immunotherapy is an effective treatment for people with locally advanced, unresectable CSCC.

What is the current status of trial NCT05574101?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2022-10-06. Estimated completion is 2026-10-06.

What conditions does trial NCT05574101 study?

This clinical trial studies the following conditions: Squamous Cell Carcinoma, Skin Cancer, Cutaneous Squamous Cell Carcinoma, Locally Advanced Cutaneous Squamous Cell Carcinoma, Locally Advanced Squamous Cell Carcinoma.

What interventions are being tested in trial NCT05574101?

The interventions under investigation include: Cemiplimab (DRUG), Radiotherapy (RADIATION).

Who is sponsoring clinical trial NCT05574101?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05574101 being conducted?

This trial has 13 study locations across Colorado, Florida, New Jersey, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.