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NCT05574101 · ClinicalTrials.gov registry record · Phase 2
A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer
A Phase 2 study of Squamous Cell Carcinoma and Skin Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 34
- Enrollment target
- 13
- Study locations
NCT05574101: Active Phase 2 study of Squamous Cell Carcinoma and Skin Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT05574101 is a Phase 2 study of Squamous Cell Carcinoma and Skin Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 34 participants, below the 103-participant average among 47 other Squamous Cell Carcinoma trials with a reported enrollment target (67% lower). The trial reports 13 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05574101, a Phase 2 study of Squamous Cell Carcinoma and Skin Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 34 participants
- Enrollment target
- 13
- Study locations
Study Summary
The purpose of the study is to see if the combination of radiation therapy and cemiplimab immunotherapy is an effective treatment for people with locally advanced, unresectable CSCC.
Primary Outcome
The primary endpoint for this study is event free survival at 18 months (week 78 +/- 3 weeks) after starting cemiplimab.
Conditions Studied
Interventions
- DRUG Cemiplimab
- RADIATION Radiotherapy
Study Locations (13)
New York
- Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (All protocol activities) - Rockville Centre
New Jersey
- Memorial Sloan Kettering Cancer Center at Basking Ridge (All Protocol Activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (All Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (All protocol activities) - Montvale
Colorado
- University of Colorado (Data Collection Only) - Aurora
Florida
- Moffitt Cancer Center (Data Collection Only) - Tampa
Ohio
- Cleveland Clinic (Data Collection Only) - Cleveland
Pennsylvania
- Fox Chase Cancer Center (Data Collection Only) - Philadelphia
South Carolina
- Medical University of South Carolina - Charleston
Washington
- University of Washington (Data Collection Only) - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2022-10-06 |
| Est. Completion | 2026-10-06 |
| Phase | Phase 2 |
What the registry record for NCT05574101 still lists
NCT05574101 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 103-participant average among 47 other Squamous Cell Carcinoma trials with a reported enrollment target (67% lower).
The record links to 7 conditions, with Squamous Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Cemiplimab is the first listed.
NCT05574101 lists 13 locations in 8 states (New York, New Jersey, Colorado).
Frequently Asked Questions
What is clinical trial NCT05574101 about?
NCT05574101 is a clinical study titled "A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer". The purpose of the study is to see if the combination of radiation therapy and cemiplimab immunotherapy is an effective treatment for people with locally advanced, unresectable CSCC.
What is the current status of trial NCT05574101?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2022-10-06. Estimated completion is 2026-10-06.
What conditions does trial NCT05574101 study?
This clinical trial studies the following conditions: Squamous Cell Carcinoma, Skin Cancer, Cutaneous Squamous Cell Carcinoma, Locally Advanced Cutaneous Squamous Cell Carcinoma, Locally Advanced Squamous Cell Carcinoma.
What interventions are being tested in trial NCT05574101?
The interventions under investigation include: Cemiplimab (DRUG), Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT05574101?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05574101 being conducted?
This trial has 13 study locations across Colorado, Florida, New Jersey, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Squamous Cell Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05574101's enrollment target sits among peer trials
34 30th of 47 higher than 18 of 47 other Squamous Cell Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Squamous Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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