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NCT04122456 · ClinicalTrials.gov registry record · NA
DNA Repair Activity in the Skin of Day and Night Shift Workers
A NA study of Skin Cancer, sponsored by Wright State University.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT04122456: Recruiting NA study of Skin Cancer, sponsored by Wright State University.
NCT04122456 is a NA study of Skin Cancer that is actively recruiting participants, run by Wright State University. The registered enrollment target is 48 participants, below the 463-participant average among 40 other Skin Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04122456, a NA study of Skin Cancer, is actively recruiting participants, sponsored by Wright State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be exposed to UVB radiation and to measure UVB responses.
Primary Outcome
Reverse transcription quantitative PCR (RT-qPCR) and immunohistochemistry will be used to measure XPA expression at the mRNA and protein level, respectively, in skin samples obtained at 8 am and 4 pm.
Conditions Studied
Interventions
- RADIATION Ultraviolet B Radiation
- OTHER No Ultraviolet B Radiation
Study Locations (1)
Ohio
- Wright State Physicians - Fairborn
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-12-07 |
| Est. Completion | 2025-12 |
| Phase | NA |
What NCT04122456 shows while recruiting
NCT04122456 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 463-participant average among 40 other Skin Cancer trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Skin Cancer appearing as the primary indexed condition, and to 2 interventions - of which Ultraviolet B Radiation is the first listed.
NCT04122456 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT04122456 about?
NCT04122456 is a clinical study titled "DNA Repair Activity in the Skin of Day and Night Shift Workers". The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be expo...
What is the current status of trial NCT04122456?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2022-12-07. Estimated completion is 2025-12.
What conditions does trial NCT04122456 study?
This clinical trial studies the following conditions: Skin Cancer.
What interventions are being tested in trial NCT04122456?
The interventions under investigation include: Ultraviolet B Radiation (RADIATION), No Ultraviolet B Radiation (OTHER).
Who is sponsoring clinical trial NCT04122456?
This trial is sponsored by Wright State University, which has 32 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04122456 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Skin Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04122456's enrollment target sits among peer trials
48 24th of 40 higher than 17 of 40 other Skin Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Skin Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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