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Schizophrenia clinical trials
76 of 318 indexed Schizophrenia trials are currently recruiting.
318 US clinical trials · 76 currently recruiting
Schizophrenia is the subject of 318 registered US clinical trials on ClinicalTrials.gov, 76 of them currently open to new participants. 90 are in Phase 3-4 (later-stage) and 87 in Phase 1-2 (earlier-stage). The most active sponsor is University of Maryland, Baltimore, running 14 of these trials.
The research picture
Schizophrenia has 318 registered US clinical trials, 76 of them open to new participants right now, about 24% of the total.
- 76
- recruiting participants now
- 24%
- of trials open to enrollment
- 90
- in Phase 3–4 (later-stage)
- 14
- top sponsor: University of Maryland, Baltimore
Active & Recent Trials
318 total, page 7 of 7
Add On Treatment for Cognitive Deficits in Schizophrenia
University of Pennsylvania
NCT01346163
An Randomized Open-Label PK Study of LY03004 Compared to Risperdal® Consta® in Stable Patients With Schizophrenia or Schizoaffective Disorder
Luye Pharma Group
NCT02186769
Effects of Antipsychotic Medications on Energy Intake and Expenditure
Washington University School of Medicine
NCT00836251
Focused Ultrasound Modulation of the Globus Pallidus Interna in Schizophrenia
NYU Langone Health
NCT05643196
Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia
Indiana University
NCT04309370
Varenicline Effects In Schizophrenic Smokers
Nathan Kline Institute for Psychiatric Research
NCT00548470
Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia
Vanda Pharmaceuticals
NCT04127058
A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women
Otsuka Pharmaceutical Development & Commercialization
NCT07305779
Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia
Beth Israel Deaconess Medical Center
NCT00434980
Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
National Institute of Mental Health (NIMH)
NCT00001768
Nicotinic Receptors and Schizophrenia
VA Office of Research and Development
NCT00952393
eMove - Dance/Movement Therapy Study
Drexel University
NCT05712928
Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation
VA Office of Research and Development
NCT03037983
An Open-Label Trial of Tocilizumab in Schizophrenia
Brian Miller
NCT01696929
Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia
University of Colorado, Denver
NCT00149734
Integrated Coping and Awareness Training
University of North Carolina, Chapel Hill
NCT02400502
A Comparison of Seroquel vs. Risperidone in Schizophrenia
AstraZeneca
NCT00034905
Generalization of Training in Schizophrenia
US Department of Veterans Affairs
NCT00108199
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 47 |
| Phase 2 | 40 |
| Phase 3 | 50 |
| Phase 4 | 40 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Schizophrenia Trial Landscape
318 indexed Schizophrenia studies · 76 recruiting (24%).
Phase mix: 90 late (III/IV) vs 87 early (I/II).
Top sponsor: University of Maryland, Baltimore (14 trials), 9 others listed. 18 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Schizophrenia?
PlainTrial tracks 318 US clinical trials for Schizophrenia, of which 76 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Schizophrenia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.