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ClinicalTrials.gov 76 recruiting now official registry

Schizophrenia clinical trials

76 of 318 indexed Schizophrenia trials are currently recruiting.

318 US clinical trials · 76 currently recruiting

Schizophrenia is the subject of 318 registered US clinical trials on ClinicalTrials.gov, 76 of them currently open to new participants. 90 are in Phase 3-4 (later-stage) and 87 in Phase 1-2 (earlier-stage). The most active sponsor is University of Maryland, Baltimore, running 14 of these trials.

The research picture

Schizophrenia has 318 registered US clinical trials, 76 of them open to new participants right now, about 24% of the total.

76
recruiting participants now
24%
of trials open to enrollment
90
in Phase 3–4 (later-stage)
14
top sponsor: University of Maryland, Baltimore
Phase 147Phase 240Phase 350Phase 440

Active & Recent Trials

318 total, page 7 of 7

COMPLETED Phase 1 16 participants

Add On Treatment for Cognitive Deficits in Schizophrenia

University of Pennsylvania

NCT01346163

COMPLETED Phase 1 16 participants

An Randomized Open-Label PK Study of LY03004 Compared to Risperdal® Consta® in Stable Patients With Schizophrenia or Schizoaffective Disorder

Luye Pharma Group

NCT02186769

COMPLETED 15 participants

Effects of Antipsychotic Medications on Energy Intake and Expenditure

Washington University School of Medicine

NCT00836251

COMPLETED Phase 2 15 participants

Focused Ultrasound Modulation of the Globus Pallidus Interna in Schizophrenia

NYU Langone Health

NCT05643196

COMPLETED NA 14 participants

Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia

Indiana University

NCT04309370

COMPLETED Phase 4 14 participants

Varenicline Effects In Schizophrenic Smokers

Nathan Kline Institute for Psychiatric Research

NCT00548470

COMPLETED Phase 1 12 participants

Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia

Vanda Pharmaceuticals

NCT04127058

COMPLETED Phase 1 12 participants

A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women

Otsuka Pharmaceutical Development & Commercialization

NCT07305779

COMPLETED NA 11 participants

Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia

Beth Israel Deaconess Medical Center

NCT00434980

COMPLETED Phase 3 10 participants

Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)

National Institute of Mental Health (NIMH)

NCT00001768

COMPLETED Phase 1 10 participants

Nicotinic Receptors and Schizophrenia

VA Office of Research and Development

NCT00952393

COMPLETED NA 10 participants

eMove - Dance/Movement Therapy Study

Drexel University

NCT05712928

COMPLETED NA 9 participants

Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation

VA Office of Research and Development

NCT03037983

COMPLETED Phase 1 8 participants

An Open-Label Trial of Tocilizumab in Schizophrenia

Brian Miller

NCT01696929

COMPLETED Phase 3 8 participants

Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia

University of Colorado, Denver

NCT00149734

COMPLETED NA 6 participants

Integrated Coping and Awareness Training

University of North Carolina, Chapel Hill

NCT02400502

COMPLETED Phase 4

A Comparison of Seroquel vs. Risperidone in Schizophrenia

AstraZeneca

NCT00034905

COMPLETED NA

Generalization of Training in Schizophrenia

US Department of Veterans Affairs

NCT00108199

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Phase Distribution

PhaseTrial count
Phase 1 47
Phase 2 40
Phase 3 50
Phase 4 40

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Schizophrenia Trial Landscape

318 indexed Schizophrenia studies · 76 recruiting (24%).

Phase mix: 90 late (III/IV) vs 87 early (I/II).

Top sponsor: University of Maryland, Baltimore (14 trials), 9 others listed. 18 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Schizophrenia?

PlainTrial tracks 318 US clinical trials for Schizophrenia, of which 76 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Schizophrenia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.