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ClinicalTrials.gov 76 recruiting now full pipeline #23 of 28,707 conditions

Schizophrenia: full-pipeline trial registry

76 of 318 indexed Schizophrenia trials are currently recruiting.

Corpus placement: #23 of 28,707 conditions by registered trial count.

318 US clinical trials · 76 currently recruiting · #23 of 28,707 conditions by registered trial count

Schizophrenia: 318 US clinical trials tracked, 76 recruiting.

Schizophrenia is the subject of 318 registered US clinical trials on ClinicalTrials.gov, 76 of them currently open to new participants. 90 are in Phase 3-4 (later-stage) and 87 in Phase 1-2 (earlier-stage). The most active sponsor is University of Maryland, Baltimore, running 14 of these trials.

Enrollment posture brief

Registry condition schizophrenia

OPEN 76 | RECR 24% | LATE 90 | EARLY 87 | RANK #23 | SPON 14

Nearest open-share peer: Dehydration (24% recruiting · 21 trials)

Acute Myeloid Leukemia51.8%Alzheimer Disease49.7%Multiple Sclerosis37.9%Type 2 Diabetes36.6%Schizophrenia (this)24%
Open-enrollment share among volume-matched conditions near Schizophrenia

Schizophrenia lists 76 open slots (24% of 318 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Schizophrenia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Schizophrenia is recruiting below its size-band peers.

    76 of 318 indexed trials (23.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Schizophrenia trials is spread across many organizations.

    University of Maryland, Baltimore accounts for 14 of 318 trials (4.4%). 129 distinct sponsors appear on at least one study for this condition label.

  3. Typical Schizophrenia enrolment sits around 83 participants.

    Median target enrolment is 83 among the 316 trials that report a genuine target (sentinel values excluded). 169 of those (53.5%) plan for fewer than 100 participants.

  4. Schizophrenia research is mostly interventional.

    290 interventional and 28 observational studies make up this index (91.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 147Phase 240Phase 350Phase 440

Open and recent trials

318 total, page 7 of 7

COMPLETED Phase 1 16 participants

Add On Treatment for Cognitive Deficits in Schizophrenia

University of Pennsylvania

NCT01346163

COMPLETED Phase 1 16 participants

An Randomized Open-Label PK Study of LY03004 Compared to Risperdal® Consta® in Stable Patients With Schizophrenia or Schizoaffective Disorder

Luye Pharma Group

NCT02186769

COMPLETED 15 participants

Effects of Antipsychotic Medications on Energy Intake and Expenditure

Washington University School of Medicine

NCT00836251

COMPLETED Phase 2 15 participants

Focused Ultrasound Modulation of the Globus Pallidus Interna in Schizophrenia

NYU Langone Health

NCT05643196

COMPLETED NA 14 participants

Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia

Indiana University

NCT04309370

COMPLETED Phase 4 14 participants

Varenicline Effects In Schizophrenic Smokers

Nathan Kline Institute for Psychiatric Research

NCT00548470

COMPLETED Phase 1 12 participants

Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia

Vanda Pharmaceuticals

NCT04127058

COMPLETED Phase 1 12 participants

A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women

Otsuka Pharmaceutical Development & Commercialization

NCT07305779

COMPLETED NA 11 participants

Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia

Beth Israel Deaconess Medical Center

NCT00434980

COMPLETED Phase 3 10 participants

Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)

National Institute of Mental Health (NIMH)

NCT00001768

COMPLETED Phase 1 10 participants

Nicotinic Receptors and Schizophrenia

VA Office of Research and Development

NCT00952393

COMPLETED NA 10 participants

eMove - Dance/Movement Therapy Study

Drexel University

NCT05712928

COMPLETED NA 9 participants

Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation

VA Office of Research and Development

NCT03037983

COMPLETED Phase 1 8 participants

An Open-Label Trial of Tocilizumab in Schizophrenia

Brian Miller

NCT01696929

COMPLETED Phase 3 8 participants

Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia

University of Colorado, Denver

NCT00149734

COMPLETED NA 6 participants

Integrated Coping and Awareness Training

University of North Carolina, Chapel Hill

NCT02400502

COMPLETED Phase 4

A Comparison of Seroquel vs. Risperidone in Schizophrenia

AstraZeneca

NCT00034905

COMPLETED NA

Generalization of Training in Schizophrenia

US Department of Veterans Affairs

NCT00108199

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Phase Distribution

PhaseTrial count
Phase 1 47
Phase 2 40
Phase 3 50
Phase 4 40

Named interventions

Most-linked intervention names on Schizophrenia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
62 trials
Olanzapine Drug
10 trials
Placebo Other
10 trials
Aripiprazole Drug
8 trials
Risperidone Drug
7 trials
placebo Drug
5 trials
Iloperidone Drug
4 trials
SEP-363856 Drug
4 trials

US sites by state

Facility locations filed on Schizophrenia trials. A trial with sites in several states counts in each.

California 131 trials
Florida 70 trials
New York 59 trials
Maryland 54 trials
Georgia 54 trials
Texas 52 trials
Illinois 47 trials
Massachusetts 46 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Schizophrenia page

318 registered trials, 76 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Schizophrenia condition card totals 318 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.