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NCT07305779 · ClinicalTrials.gov registry record · Phase 1

A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women

A Phase 1 study of Schizophrenia, sponsored by Otsuka Pharmaceutical Development & Commercialization.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT07305779 is a Phase 1 study of Schizophrenia that has completed, run by Otsuka Pharmaceutical Development & Commercialization. The registered enrollment target is 12 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07305779, a Phase 1 study of Schizophrenia, has completed, sponsored by Otsuka Pharmaceutical Development & Commercialization.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess the effect of cytochrome P450 isoenzyme 2D6 (CYP2D6) inhibition by quinidine on the pharmacokinetic (PK) parameters of a single dose SEP-380135 in healthy adult participants.

Conditions Studied

Interventions

  • DRUG SEP-380135
  • DRUG Quinidine Gluconate

Study Locations (1)

Kansas

  • Dr. Vince Clinical Research - Overland Park

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2025-03-07
Est. Completion 2025-05-03
Phase Phase 1

What the Registry Record Tells You About NCT07305779

The ClinicalTrials.gov registry entry for NCT07305779 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (95% lower). The listed sponsor is Otsuka Pharmaceutical Development & Commercialization, which has 221 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which SEP-380135 is the first listed.

NCT07305779 reports 1 study location spanning 1 distinct geographic area - top geographies include Kansas.

Frequently Asked Questions

What is clinical trial NCT07305779 about?

NCT07305779 is a clinical study titled "A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women". The purpose of this study is to assess the effect of cytochrome P450 isoenzyme 2D6 (CYP2D6) inhibition by quinidine on the pharmacokinetic (PK) parameters of a single dose SEP-380135 in healthy adult participants.

What is the current status of trial NCT07305779?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2025-03-07. Estimated completion is 2025-05-03.

What conditions does trial NCT07305779 study?

This clinical trial studies the following conditions: Schizophrenia.

What interventions are being tested in trial NCT07305779?

The interventions under investigation include: SEP-380135 (DRUG), Quinidine Gluconate (DRUG).

Who is sponsoring clinical trial NCT07305779?

This trial is sponsored by Otsuka Pharmaceutical Development & Commercialization, which has 221 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07305779 being conducted?

This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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