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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Sarcoma,Soft Tissue: early-phase trial registry

3 of 13 indexed Sarcoma,Soft Tissue trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 3 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Sarcoma,Soft Tissue: 13 US clinical trials tracked, 3 recruiting.

Sarcoma,Soft Tissue is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition sarcomasoft-tissue

OPEN 3 | RECR 23% | LATE 2 | EARLY 9 | RANK #1315 | SPON 4

Nearest open-share peer: Endometrial Serous Adenocarcinoma (23% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Sarcoma,Soft Tissue (this)23%
Open-enrollment share among volume-matched conditions near Sarcoma,Soft Tissue

Sarcoma,Soft Tissue lists 3 open slots (23% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Sarcoma,Soft Tissue on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Sarcoma,Soft Tissue is recruiting below its size-band peers.

    3 of 13 indexed trials (23.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Sarcoma,Soft Tissue research.

    Memorial Sloan Kettering Cancer Center accounts for 4 of 13 trials (30.8%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Sarcoma,Soft Tissue trials plan to enrol fewer than 100 people.

    Median target enrolment is 39 among the 13 trials that report a genuine target (sentinel values excluded). 9 of those (69.2%) plan for fewer than 100 participants.

  4. Sarcoma,Soft Tissue research is mostly interventional.

    12 interventional and 1 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 26Phase 32

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 2 140 participants

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

EpicentRx

NCT04673942

RECRUITING Phase 1 98 participants

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Memorial Sloan Kettering Cancer Center

NCT04577014

RECRUITING Phase 2 50 participants

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Wake Forest University Health Sciences

NCT07291297

ACTIVE NOT RECRUITING Phase 3 333 participants

A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)

Intensity Therapeutics

NCT06263231

ACTIVE NOT RECRUITING Phase 2 16 participants

A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma

Memorial Sloan Kettering Cancer Center

NCT05886634

ACTIVE NOT RECRUITING Early Phase 1 9 participants

Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma

University of California, Irvine

NCT05488366

ACTIVE NOT RECRUITING Phase 2 8 participants

A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA

Memorial Sloan Kettering Cancer Center

NCT05515575

ACTIVE NOT RECRUITING Phase 1 6 participants

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Washington University School of Medicine

NCT05813327

ACTIVE NOT RECRUITING Phase 2 2 participants

Neoadjuvant Intralesional Injection of Talimogene Laherparepvec

John Rieth

NCT06660810

COMPLETED Phase 3 120 participants

Comparison of Gemcitabine v. Gemcitabine Plus Docetaxel in Unresectable Soft Tissue Sarcoma

Memorial Sloan Kettering Cancer Center

NCT00142571

COMPLETED Phase 2 101 participants

A Study of LY573636-Sodium in the Treatment of Patients With Metastatic Soft Tissue Sarcoma

Eli Lilly and Company

NCT00490451

COMPLETED 39 participants

Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma

The Cleveland Clinic

NCT02897128

COMPLETED NA 9 participants

(SBRT) and (ART) for Pulmonary Metastases From Soft Tissue Sarcomas

Medical College of Wisconsin

NCT01949506

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 2

Named interventions

Most-linked intervention names on Sarcoma,Soft Tissue records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
2 trials
Docetaxel Drug
2 trials
LY573636-sodium Drug
1 trials
Observational Only - Transcutaneous Oxygen Measurement Other
1 trials
INT230-6 Drug
1 trials
Neoadjuvant Radiation Radiation
1 trials
ADI PEG20 Drug
1 trials
Etrumadenant Drug
1 trials

US sites by state

Facility locations filed on Sarcoma,Soft Tissue trials. A trial with sites in several states counts in each.

New York 5 trials
Ohio 3 trials
California 3 trials
Texas 2 trials
New Jersey 2 trials
North Carolina 2 trials
Iowa 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Sarcoma,Soft Tissue page

13 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sarcoma,Soft Tissue condition card totals 13 registered trials; most-linked intervention Gemcitabine; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.