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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Endometrial Serous Adenocarcinoma: early-phase trial registry

3 of 13 indexed Endometrial Serous Adenocarcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 3 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Endometrial Serous Adenocarcinoma: 13 US clinical trials tracked, 3 recruiting.

Endometrial Serous Adenocarcinoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 8 of these trials.

Enrollment posture brief

Registry condition endometrial-serous-adenocarcinoma

OPEN 3 | RECR 23% | LATE 3 | EARLY 7 | RANK #1315 | SPON 8

Nearest open-share peer: Infant, Small for Gestational Age (23% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Endometrial Serous Adeno (th…23%
Open-enrollment share among volume-matched conditions near Endometrial Serous Adenocarcinoma

Endometrial Serous Adenocarcinoma lists 3 open slots (23% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Endometrial Serous Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Endometrial Serous Adenocarcinoma is recruiting below its size-band peers.

    3 of 13 indexed trials (23.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Endometrial Serous Adenocarcinoma research.

    National Cancer Institute (NCI) accounts for 8 of 13 trials (61.5%). 4 distinct sponsors appear on at least one study for this condition label.

  3. Typical Endometrial Serous Adenocarcinoma enrolment sits around 188 participants.

    Median target enrolment is 188 among the 13 trials that report a genuine target (sentinel values excluded). 5 of those (38.5%) plan for fewer than 100 participants.

  4. Endometrial Serous Adenocarcinoma research is mostly interventional.

    11 interventional and 2 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 24Phase 33

Open and recent trials

13 total, page 1 of 1

RECRUITING 1,000 participants

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers

M.D. Anderson Cancer Center

NCT05049538

RECRUITING Phase 3 360 participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

National Cancer Institute (NCI)

NCT05256225

RECRUITING Phase 3 188 participants

Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer

University of Utah

NCT03422198

ACTIVE NOT RECRUITING Phase 3 813 participants

Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

National Cancer Institute (NCI)

NCT03914612

ACTIVE NOT RECRUITING Phase 2 349 participants

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

National Cancer Institute (NCI)

NCT00977574

ACTIVE NOT RECRUITING Phase 2 288 participants

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

National Cancer Institute (NCI)

NCT03660826

ACTIVE NOT RECRUITING NA 101 participants

PET/CT and Lymph Node Mapping in Finding Lymph Node Metastasis in Patients With High-Risk Endometrial Cancer

M.D. Anderson Cancer Center

NCT01737619

ACTIVE NOT RECRUITING Phase 1 50 participants

TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors

National Cancer Institute (NCI)

NCT02142803

ACTIVE NOT RECRUITING Early Phase 1 12 participants

Testing the Response to the Anti-cancer Drug, Triapine, in Uterine Cancers Using Markers From the Tissue at the Time of Hysterectomy

National Cancer Institute (NCI)

NCT04494113

COMPLETED 360 participants

Biomarkers in Blood and Tissue Samples From Patients With Uterine Cancer

Gynecologic Oncology Group

NCT01344837

COMPLETED Phase 2 37 participants

Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer

National Cancer Institute (NCI)

NCT01307631

COMPLETED Phase 2 37 participants

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Gynecologic Oncology Group

NCT01225887

COMPLETED Phase 1 26 participants

Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer

National Cancer Institute (NCI)

NCT01935973

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4
Phase 3 3

Named interventions

Most-linked intervention names on Endometrial Serous Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
5 trials
Biospecimen Collection Procedure
4 trials
Computed Tomography Procedure
3 trials
Carboplatin Drug
3 trials
Bevacizumab Biological
2 trials
Paclitaxel Drug
2 trials
Microarray Analysis Genetic
1 trials
Immunohistochemistry Staining Method Other
1 trials

US sites by state

Facility locations filed on Endometrial Serous Adenocarcinoma trials. A trial with sites in several states counts in each.

Texas 5 trials
California 5 trials
Arizona 4 trials
Pennsylvania 3 trials
Maryland 3 trials
Illinois 3 trials
Connecticut 3 trials
Arkansas 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Endometrial Serous Adenocarcinoma page

13 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Endometrial Serous Adenocarcinoma condition card totals 13 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.